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Abstract Background Managing the simultaneous treatment of HIV/AIDS and tuberculosis (TB) increases the risk of adverse reactions, drug interactions, and challenges to treatment adherence. To address these complexities, ...

Rapid establishment of herd immunity with vaccination is effective to combat emerging infectious diseases. Although the incorporation of adjuvant and intradermal (ID) injection could augment early responses to the vaccin...

Reconstructing the early spatiotemporal dynamics of emerging infectious diseases (EIDs) is essential for effective public health response but remains difficult due to reporting delays, heterogeneous surveillance systems,...

The rising concern of antimicrobial resistance, coupled with the continually challenging management of complicated diseases such as cancer, has provided momentum toward precision molecular medicine. This review provides ...

The causes of cow mortality were studied depending on the level of homozygosity and genomic inbreeding of sires. Genomic data from 307 Holstein and Black-and-White bulls with 34,280 daughters were used. To calculate the ...

Intensive immunosuppressive therapy in renal transplant patients increases the risk for infectious diseases. Varicella zoster virus (VZV) infection is one of these infectious diseases and can occur either primarily or wi...

ABSTRACT This study aimed to investigate how type of hoof injury and corrective trimming alter the behavior of dairy cows. Thirty-four lactating Holstein and Jersey cows were used. They were scored for lameness score on ...

Introduction . Genital herpes is one of the most common sexually transmitted viral diseases and the most common cause of mucous membrane ulcerations in the genital area. The number of sexually transmitted infections caus...

Serum sickness is an immune complex-mediated hypersensitivity reaction, classically manifested by the triad of fever, rash, and arthralgias. It results from the formation and deposition of antigen–antibody complexes, l...

BackgroundAlthough drug rash with eosinophilia and systemic symptoms (DRESS) and anticonvulsant hypersensitivity syndrome are well-known complications of anti-seizure medications (ASMs), lesser-known immunologic complica...

Dedicator of cytokinesis 8 (DOCK8) deficiency is a rare autosomal recessive combined immunodeficiency marked by severe atopy, recurrent viral and bacterial infections, high immunoglobulin E, eosinophilia, and lymphopenia...

X-linked agammaglobulinemia (XLA) is an inherited inborn error of immunity caused by low or absent Bruton tyrosine kinase activity, resulting in impaired B cell development, poor immunoglobulin production, and severe, re...

IntroductionMacrophage activation syndrome (MAS) is a rare, potentially fatal hyperinflammatory complication of autoimmune disease, characterized by fever, cytopenias, hyperferritinemia, and multiorgan involvement (1). I...

Hypereosinophilic syndrome (HES) is characterized by blood or tissue hypereosinophilia leading to organ damage or dysfunction. HES is most commonly secondary or idiopathic, but may be primary (myeloid) or familial. Here,...

BackgroundT cell–mediated hepatitis is an uncommon cause of acute pediatric liver injury. Most patients respond to steroids, but management of refractory disease remains challenging. We describe four patients with non-...

BACKGROUND: In an era of shifting global agendas and expanded emphasis on non-communicable diseases and injuries along with communicable diseases, sound evidence on trends by cause at the national level is essential. The...

Autophagy is an important intracellular degradative process that delivers cytoplasmic proteins to lysosome for degradation. Dysfunction of autophagy is implicated in several human diseases, such as neurodegenerative dise...

Fil: Carrica, Mariela del Carmen. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquímicas de Buenos Aires; Argent...

Fil: Buch, Alfonso. Universidad Nacional de Quilmes. Centro de Estudios e Investigaciones; Argentina. Existen ciertos patrones culturales que, como las epidemias, se repiten y retornan. Uno de ellos es la tendencia a res...

Fil: Scian, Romina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Inmunología, Genética y Metabolismo; Argentina. La brucelosis osteoarticul...

In December, 2019, a local outbreak of pneumonia of initially unknown cause was detected in Wuhan (Hubei, China), and was quickly determined to be caused by a novel coronavirus,1WHOWHO statement regarding cluster of pneu...

Abstract Emerging infectious diseases, such as severe acute respiratory syndrome (SARS) and Zika virus disease, present a major threat to public health 1–3 . Despite intense research efforts, how, when and where new di...

Materias / palabras clave: vaccines, microbiology, infectious diseases, immunology, proteomics; Medicine: Internal medicine: Infectious and parasitic diseases

Materias / palabras clave: human infectious diseases, epidemiology, vaccine, pathogenesis, public health policies; Medicine: Internal medicine: Infectious and parasitic diseases