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Abstract Background It is estimated that almost all women undergoing cesarean section experience some pain in the immediate postpartum period. In the face of pain that limits self-care and care for the newborn, antalgic ...

Contamination with anthropogenic debris, such as plastic and paint particles, has been widely investigated in the global marine environment. However, there is a lack of information regarding their presence in marine prot...

BackgroundSleep disruption(SD) has been shown to amplify inflammatory signaling and promote pain hypersensitivity, but how inflammation interacts with brain functional alterations to drive pain sensitization remains uncl...

ABSTRACT Introduction Diabetic neuropathy, the most common long‐term complication of diabetes, frequently presents as painful diabetic peripheral neuropathy (pDPN), significantly impairing patients' quality of life. Pr...

Hui Wu,1– 4,* Meiyan Zhou,2,* Songtao Liu,2,* Yu Qi,2 Fan Zhou,1– 4 Liwei Wang,1,2 Conghai Fan1,3,4 1College of Anesthesiology, Xuzhou Medical University, Xuzhou, Jiangsu, People’s Republic ...

BackgroundChronic low back pain (CLBP), with or without radicular pain (RP), is a major cause of disability and reduced quality of life. Psychological comorbidities such as depression, anxiety, and chronic pain disorder ...

James S Cho,1,2 Julia Zhu,2 Pritesh Topiwala,1,2 David Hao1,2 1Department of Anesthesiology, Mass General Brigham, Boston, MA, USA; 2Harvard Medical School, Boston, MA, USACorrespondence: David Hao, Department of Anesthe...

ABSTRACT Background Our study aimed to investigate the association between social isolation and chest pain, and to evaluate the relationship between social isolation and all‐cause mortality stratified by the presence o...

Abstract Background Chronic low back pain (CLBP) is a common musculoskeletal symptom associated with spinal disorders, impairing quality of life while imposing significant medical and socioeconomic burdens. Traditional l...

Introduction. The 2025 FDA approval of suzetrigine (Journavx) ended a 25-year stagnation in analgesic development. This introduced a paradigm shift in pain management. As a first-in-class, highly selective NaV1.8 sodium...

Sharon Wang-Price,1 Jason Zafereo,2 Khalid Alkhathami,3,* Yousef Alshehre,4,* Hui-Ting Goh1 1School of Physical Therapy, College of Health Sciences, Texas Woman’s University, Dallas, TX, USA; 2Departmen...

Abstract Background Neuropsychiatric symptoms (NPS) are highly prevalent in nursing home residents. The main aims of this study were to examine whether music-based care (MBC) had sustained effects on NPS in nursing home ...

ObjectiveTo evaluate the effects of various transcranial magnetic stimulation (TMS) parameters—including stimulation duration, intensity, pulse number, frequency, and target region—on pain scores in patients with neu...

Ocular prosthetics are mainly created to meet the aspect of esthetic consideration. The paint application in ocular prosthetics construction is remaining an option for Prosthodontist. This study aims to examine the effec...

Abstract Background Chronic neuropathic pain is frequently accompanied by anxiety and depression, yet the cortical circuit mechanisms underlying this comorbidity remain unclear. The medial orbitofrontal cortex (mOFC) is ...

Abstract Objective The aim of the study was to identify non-pharmacological therapeutic resources used by physiotherapists for pain relief during labor and childbirth. Methods This is a cross-sectional study conducte...

Objetivo: analisar o uso da vídeo-minilaparoscopia no diagnóstico das causas de algia pélvica, bem como sua aplicabilidade. Métodos: foram estudadas prospectivamente 32 pacientes com algia pélvica, com idade média ...

Abstract Fear and pain are two frequently co-occurring states that mammals need to orchestrate to ensure survival. Nevertheless, how the brain dynamically prioritizes between them remains poorly understood. Here, we demo...

IntroductionCyclin-dependent kinase 5 (Cdk5) plays a critical role in pain transmission by phosphorylating key nociceptive proteins. One of its recently identified substrates, the P2X2 subunit, is part of the P2X2/3 puri...

Introduction Pain, a common symptom of coronary artery disease (CAD), changes physiological parameters, which can aggravate ischemia and increase cardiac workload. Acupressure, as a complementary therapy, can be benefici...

# Background Rotator cuff weakness is common in patients with shoulder pain, but the underlying causes are unclear when tendons are structurally intact. Atrophy is well established after full-thickness tears, but it is u...

Introduction One in five people experience chronic pain globally, yet management remains suboptimal and discrepant guideline recommendations are common. To increase pain literacy and improve concordance between evidence ...

Abstract Background Altered pain processing and central sensitization are key mechanisms underlying migraine. Although quantitative sensory testing (QST) objectively assesses sensory thresholds, its clinical implications...

Background Patients who suffer comorbidity of major depressive disorder (MDD) and chronic pain (CP) maintain a complex interplay between maladaptive prospective memory (PM) and retrospective memory (RM) with physical pai...