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120 resultados encontrados.

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Protocol optimization for the detection of Trypanosoma cruzi DNA in açai (Euterpe oleraceae) pulp
Artículo
Acceso abierto Artículo DOAJ
Gabrielle Virgínia Ferreira CARDOSO et al · Instituto Nacional de Pesquisas da Amazônia · 2021 · ISSN 0044-5967
ABSTRACT Chagas disease, caused by the protozoan Trypanosoma cruzi, has often been linked to oral transmission through açai consumption. Molecular methods that allow fast and accurate identification of the pathogen are ...
LCC LCC:Science (General)Idioma eng
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Open Access
Regional Hereditary Cancer Program in Chile: A scalable model of genetic counseling and molecular diagnosis to improve clinical outcomes for patients with hereditary cancer across Latin America
Artículo
Acceso abierto Artículo CONICET Digital
Landeros, Natalia et al · BioMed Central · 2024 · ISSN 0717-6287
Background Breast cancer is a leading cause of cancer-related mortality worldwide, with hereditary forms accounting for approximately 10% of cases. In Chile, significant gaps exist in genetic counseling and testing, part...
Idioma eng
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Open Access
Stability and profiling of urinary microRNAs in healthy cats and cats with pyelonephritis or other urological conditions
Artículo
Acceso abierto Artículo DOAJ
Lisbeth R. Jessen et al · Oxford University Press · 2020 · ISSN 0891-6640
Abstract Background Specific biomarkers of pyelonephritis (PN) in cats are lacking. MicroRNAs (miRNAs) have diagnostic potential in human nephropathies. Objectives To investigate the presence/stability of miRNAs in whole...
LCC TENDOlZldGVyaW5hcnkgbWVkaWNpbmU~Idioma eng
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Open Access
The Levels of Serum Immunoglobulin A, G and M in Oral Inflammatory Cysts before and after Surgical Therapy
Artículo
Acceso abierto Artículo DOAJ
Dimitrovski Oliver et al · Balkan Stomatological Society · 2018 · ISSN 2335-0245
Background/Aim: Cysts which appear in the orofacial region are represented as common pathological changes which underlying mechanism of development is still not fully clear. In recent years, a dominant role in the pathog...
LCC TENDOkRlbnRpc3RyeQ~~Idioma eng
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Open Access
Utilization of care and alignment of screening with NCCN guidelines for patients with Lynch syndrome: a retrospective cohort study
Artículo
Material complementario disponible Artículo DOAJ
Christina Lowry et al · BMC · 2026 · ISSN 1897-4287
Abstract Objectives Determine the proportion of patients with Lynch syndrome who received guideline-concordant care according to NCCN guidelines during the study period (2015–2018). Methods A retrospective cohort study...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~; LCC:GeneticsIdioma eng
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Material complementario
A Novel De Novo KMT2D Genetic Variant in Kabuki Syndrome: A Case Report
Artículo
Acceso abierto Artículo DOAJ
Marija Rowane et al · Rockefeller University Press · 2026 · ISSN 3065-8993
IntroductionKabuki syndrome (KS) is a rare, complex, multisystem, neurodevelopmental congenital disorder with characteristic phenotypic anomalies and pathogenic genetic variants of the KMT2D or KDM6A genes. KS is highly ...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Open Access
A cohort study of fetal urinary tract abnormalities and chromosomal copy number variations: a retrospective analysis of 9-year data
Artículo
Acceso abierto Artículo DOAJ
Lin Chen et al · Springer · 2026 · ISSN 1432-0711
Abstract Objective To investigate the association between ultrasonically detected fetal urinary system abnormalities and chromosomal copy number variations (CNVs) in Heilongjiang Province, northeastern China. Methods Coh...
LCC TENDOkd5bmVjb2xvZ3kgYW5kIG9ic3RldHJpY3M~Idioma eng
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Open Access
A novel EVC2 splice-site variant expands the mutational and phenotypic spectrum of Weyers acrofacial dysostosis
Artículo
Acceso abierto Artículo DOAJ
Ai Chen et al · BMC · 2026 · ISSN 1755-8794
Abstract Background Weyers acrofacial dysostosis (WAD) is a rare autosomal dominant ciliopathy caused by heterozygous pathogenic variants in the EVC2 gene. The classic phenotype includes short stature, dental anomalies, ...
LCC LCC:Internal medicine; LCC:GeneticsIdioma eng
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Open Access
ACVIM consensus statement on pancreatitis in cats
Artículo
Acceso abierto Artículo DOAJ
Marnin A. Forman et al · Oxford University Press · 2021 · ISSN 0891-6640
Abstract Background Pancreatitis in cats, although commonly diagnosed, still presents many diagnostic and management challenges. Objective To summarize the current literature as it relates to etiology, pathogenesis, diag...
LCC TENDOlZldGVyaW5hcnkgbWVkaWNpbmU~Idioma eng
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Open Access
Amblyomma scalpturatum Neumann, 1906 (Acari: Ixodidae): confirmation in Acre State, Brazil, and description of parasitism in a human
Artículo
Material complementario disponible Artículo DOAJ
André de Abreu Rangel Aguirre et al · Colégio Brasileiro de Parasitologia Veterinária · ISSN 1984-2961
Abstract Amblyomma scalpturatum is a tick species that is unique to South America. It is commonly associated with the Amazon biome and has been reported in some Brazilian states. This tick species exhibits host specifici...
LCC LCC:Animal cultureIdioma eng
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Material complementario
Analysis of novel zinc-binding proteins in the cell wall of Corynebacterium diphtheriae
Artículo
Acceso abierto Artículo DOAJ
Eric D. Peng et al · American Society for Microbiology · 2025 · ISSN 0021-9193
ABSTRACT Zinc is a critical nutrient for all living organisms, including bacterial pathogens such as Corynebacterium diphtheriae, the causative agent of the severe human respiratory disease diphtheria. As such, zinc acqu...
LCC LCC:MedicineIdioma eng
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Open Access
Antibiofilm effect of Zuccagnia punctata on Listeria monocytogenes FBUNT as an anti-quorum sensing strategy
Revista
Acceso abierto Revista CONICET Digital
Melian, Constanza Victoria et al · Tech Science Press · 2021 · ISSN 0327-9545
Listeria monocytogenes is a foodborne pathogen able to survive in a wide range of environments even at refrigerated conditions. Their persistence in food processing environments is due to its ability to form biofilm. Bac...
Idioma eng
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Open Access
Antimicrobial Activity of Some Trichoderma spp. against Different Kinds of Fungal and Bacterial Isolates
Artículo
Acceso abierto Artículo DOAJ
Omar Al-Obaidy · University of Mosul, College of Education for Pure Science · 2019 · ISSN 1812-125X
Two types of the fungus Trichoderma were chosen, these are T.viride and T.harzianum. The activity of these fungi were tested against different kinds of plant and human pathogenic fungi. After screening , the fungus T.har...
LCC TENDOkVkdWNhdGlvbg~~; LCC:Science (General)Idioma eng
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Open Access
Applications and future challenges of Bacillus and its derivatives in crop protection
Artículo
Acceso abierto Artículo DOAJ
Abhishek Kumar et al · Springer Nature · 2026 · ISSN 3005-1207
Abstract Many pests and diseases affect agricultural and commercial crops, resulting in potential yield losses. It has been shown that microbial biocontrol agents, such as Bacillus species, are efficient alternatives to ...
LCC TENDOlBsYW50IGN1bHR1cmU~; TENDOkJvdGFueQ~~Idioma eng
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Open Access
Bacteriological Profile and Antibiotic Resistance Patterns of Wastewater Effluents in 2 Hospitals of Ethiopia
Artículo
Acceso abierto Artículo DOAJ
Baye Maru Derso et al · SAGE Publishing · 2026 · ISSN 1178-6302
The wastewater effluent is a hotspot for a multitude of microorganisms, including environmental pathogens, true human pathogens, and animal pathogens. In the absence of standardized wastewater treatment facilities, these...
LCC TENDOkVudmlyb25tZW50YWwgc2NpZW5jZXM~; LCC:Public aspects of medicineIdioma eng
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Open Access
Case Report: Beyond conventional diagnostics: mNGS support in a complex immunocompromised patient diagnosis
Artículo
Acceso abierto Artículo DOAJ
Rossana Scutari et al · Frontiers Media S.A · 2026 · ISSN 2296-858X
Next-generation metagenomic sequencing (mNGS) enables the direct and unbiased detection of pathogens from clinical samples, overcoming the limitations of standard methods. It is particularly valuable in immunocompromised...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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Open Access
Characterization of microbiota, antibiotic resistance genes and virulence factors in retail Flammulina velutipes in Beijing City
Artículo
Acceso abierto Artículo DOAJ
NONG Yingying et al · The Editorial Office of Chinese Journal of Food Hygiene · 2025 · ISSN 1004-8456
ObjectiveTo analyze the microbial community structure, distribution of antibiotic resistance genes and virulence factors in Flammulina velutipes using metagenomic sequencing, and explore its potential food safety ris...
LCC TENDOkZvb2QgcHJvY2Vzc2luZyBhbmQgbWFudWZhY3R1cmU~; LCC:Nutrition. Foods and food supplyIdioma zho
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Open Access
Clinical characterization and structural modeling of a novel de novo SPTBN1 missense variant in a Chinese child
Artículo
Acceso abierto Artículo DOAJ
Junyu Wang et al · BMC · 2026 · ISSN 1471-2431
Abstract Background SPTBN1 encodes βII-spectrin, a cytoskeletal protein essential for neuronal structure and function. Pathogenic variants in this gene cause a neurodevelopmental disorder known as DDISBA (Developmental ...
LCC TENDOlBlZGlhdHJpY3M~Idioma eng
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Open Access
Comparison of the Bioeffect of Different Locally Isolated Antifungal Bacteria
Artículo
Acceso abierto Artículo DOAJ
ِِAyad Al-Obaidy · University of Mosul, College of Education for Pure Science · 1999 · ISSN 1812-125X
ABSTRACT Thirteen different soil samples near the rhizosphere were collected from different places in Mosul city/ Iraq. Sixty six different bacterial isolates were isolated from these samples. After testing the capabilit...
LCC TENDOkVkdWNhdGlvbg~~; LCC:Science (General)Idioma eng
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Open Access
Development of a Disease Activity Score to Assess Treatment Success in Patients with NFKB1 Mutations
Artículo
Acceso abierto Artículo DOAJ
Katharina Thoma et al · Rockefeller University Press · 2026 · ISSN 3065-8993
BackgroundNFKB1 encodes for the p105/p50 nuclear factor-kappa-B (NF-kB1) transcription factors. Heterozygous mutations in NFKB1 may lead to NF-kB1 insufficiency, which may result in a multiorgan disease. Here, we aimed t...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Open Access
Early detection of Ascochyta blight (Ascochyta rabiei) of chickpea by traditional PCR
Artículo
Acceso abierto Artículo CONICET Digital
Valetti, Lucio et al · Elsevier · 2021 · ISSN 0261-2194
Ascochyta blight is the major disease affecting chickpea (Cicer arietinum) around the world. Since the first report of Ascochyta rabiei's isolation in Argentina in 2012, the pathogen has caused severe economic losses in ...
Idioma eng
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Open Access
Effect of aqueous and alcoholic extract of Eucalyptus camaldulensis Dehn leaves in growth of root rot fungi of Biota orientails L. in vitro
Artículo
Acceso abierto Artículo DOAJ
muhannad younis et al · University of Mosul, College of Education for Pure Science · 2022 · ISSN 1812-125X
Root Rot disease is one of important disease which caused great damage for Biota orientails and this was evident in the private forest nurseries in Mosul, for three nurseries in the Al-Faisaliah area, three nurseries in ...
LCC TENDOkVkdWNhdGlvbg~~; LCC:Science (General)Idioma eng
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Open Access
Ehrlichia canis (Jaboticabal strain) induces the expression of TNF-α in leukocytes and splenocytes of experimentally infected dogs Amostra Ehrlichia canis (Jaboticabal) induz a expressão de TNF-α em leucócitos e esplenócitos de cães experimentalmente infectados
Artículo
Acceso abierto Artículo DOAJ
Joice Lara Maia Faria et al · Colégio Brasileiro de Parasitologia Veterinária · 2011 · ISSN 0103-846X
Canine ehrlichiosis is caused by the bacterium Ehrlichia canis and is characterized by a systemic febrile disease of unknown pathogenesis. This study evaluated the expression of cytokines TNF-α, IL-10, IFN-γ, i...
LCC LCC:Animal cultureIdioma eng
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Open Access
Emerging role of metagenomic next‐generation sequencing in infectious disease diagnostics: Clinical integration and future directions
Artículo
Acceso abierto Artículo DOAJ
Tingting Fang et al · Wiley · 2026 · ISSN 2770-100X
Abstract Infectious disease diagnostics has been transformed by metagenomic next‐generation sequencing (mNGS), an unbiased approach that detects bacteria, viruses, fungi, and parasites in a single assay. By sequencing ...
LCC TENDOk1pY3JvYmlvbG9neQ~~Idioma eng
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