NODOVOX | Discovery

Deciphering the function of Com_YlbF domain-containing proteins in Staphylococcus aureus

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Deciphering the function of Com_YlbF domain-containing proteins in Staphylococcus aureus

Zayda-Lorena Corredor-Rozo et al · American Society for Microbiology · 2025 · ISSN 0021-9193

ABSTRACT The Com_YlbF domain-containing proteins inhibit sporulation, competition, and biofilm formation by affecting the activity of ribonuclease RNase-Y in Bacillus subtilis. Similar Com_YlbF proteins are found in Stap...

LCC LCC:MedicineIdioma eng

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Decoding Dysregulation of DNA Methylation in Epigenetics of Idiopathic Pulmonary Fibrosis

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Decoding Dysregulation of DNA Methylation in Epigenetics of Idiopathic Pulmonary Fibrosis

Guorao Wu et al · Wiley · 2026 · ISSN 1916-7245

Idiopathic pulmonary fibrosis (IPF), the continuously advancing and frequently lethal idiopathic interstitial pneumonia, is pathologically characterized by abnormal deposition of extracellular matrix constituents, leadin...

LCC TENDOkRpc2Vhc2VzIG9mIHRoZSByZXNwaXJhdG9yeSBzeXN0ZW0~Idioma eng

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Does inflammation play a role in development of necrobiosis lipoidica?

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Does inflammation play a role in development of necrobiosis lipoidica?

Iwona Słowik-Kwiatkowska et al · Termedia Publishing House · 2014 · ISSN 0033-2526

Introduction. Necrobiosis lipoidica (NL) is a granulomatous skin disease of still only partially known pathogenesis. Microangiopathy is considered as one of the most important processes in NL, and vascular endothelial ...

LCC LCC:Medicine; LCC:DermatologyIdioma eng

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Dysfunctional astrocytes regulate excitatory neurons via cell adhesion and vascular lesions in patients with Alzheimer’s disease

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Dysfunctional astrocytes regulate excitatory neurons via cell adhesion and vascular lesions in patients with Alzheimer’s disease

Yuan-Yuan Zhang et al · BMC · 2026 · ISSN 1479-5876

Abstract Background Alzheimer’s disease (AD) is a progressive neurodegenerative disorder. Its complex pathogenesis remains unclear, and no specific drugs are available for treatment. Current treatments focus mainly on ...

LCC LCC:MedicineIdioma eng

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Dysregulated m6A RNA methylation in tuberculosis: association with altered methyltransferase expression and immune responses

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Dysregulated m6A RNA methylation in tuberculosis: association with altered methyltransferase expression and immune responses

Yunyi Xu et al · BMC · 2026 · ISSN 1471-2334

Abstract Objective Tuberculosis (TB) remains a global health threat with an incompletely understood pathogenesis. The RNA epigenetic modification N6-methyladenosine (m6A) is a key regulator of immune responses in various...

LCC TENDOkluZmVjdGlvdXMgYW5kIHBhcmFzaXRpYyBkaXNlYXNlcw~~Idioma eng

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Efficacy of vitamin C supplementation during pregnancy in the prevention of preterm birth: a systematic review and meta-analysis

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Efficacy of vitamin C supplementation during pregnancy in the prevention of preterm birth: a systematic review and meta-analysis

Ana Gabriela Alves Pereira et al · Federação Brasileira das Sociedades de Ginecologia e Obstetrícia · 2025 · ISSN 0100-7203

Abstract Objective: Preterm birth is a leading global cause of neonatal mortality and morbidity, with oxidative stress playing a role in its pathogenesis. Vitamin C, a powerful antioxidant, may help reduce this risk. Th...

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Ehrlichia canis (Jaboticabal strain) induces the expression of TNF-α in leukocytes and splenocytes of experimentally infected dogs Amostra Ehrlichia canis (Jaboticabal) induz a expressão de TNF-α em leucócitos e esplenócitos de cães experimentalmente infectados

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Joice Lara Maia Faria et al · Colégio Brasileiro de Parasitologia Veterinária · 2011 · ISSN 0103-846X

Canine ehrlichiosis is caused by the bacterium Ehrlichia canis and is characterized by a systemic febrile disease of unknown pathogenesis. This study evaluated the expression of cytokines TNF-α, IL-10, IFN-γ, i...

LCC LCC:Animal cultureIdioma eng

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Evaluation of Angiogenic Factors (PlGF and sFlt-1) in Pre-eclampsia Diagnosis

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Evaluation of Angiogenic Factors (PlGF and sFlt-1) in Pre-eclampsia Diagnosis

Catherine Primo Nogueira de Sá et al · Federação Brasileira das Sociedades de Ginecologia e Obstetrícia · 2020 · ISSN 0100-7203

Abstract Objective: Recent observations support the hypothesis that an imbalance between angiogenic factors has a fundamental role in the pathogenesis of pre-eclampsia and is responsible for the clinical manifestations ...

LCC TENDOkd5bmVjb2xvZ3kgYW5kIG9ic3RldHJpY3M~Idioma eng

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Evaluation of Oxidative Stress in Primary Glomerulonephritis with Serum Level of Ischemia Modified Albumin (IMA)

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Evaluation of Oxidative Stress in Primary Glomerulonephritis with Serum Level of Ischemia Modified Albumin (IMA)

Ayşegül ORUÇ et al · Turkish Society of Nephrology · 2019 · ISSN 2667-4440

OBJECTIVE: Oxidative stress (OS) is described as the imbalance of oxidative and anti-oxidative systems towards oxidants and plays a role in the pathogenesis of GN. In many studies, ischemiamodified albumin (IMA) is ident...

LCC LCC:Internal medicine; TENDOlBlZGlhdHJpY3M~Idioma eng

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Evaluation of gallbladder motility assessed by ultrasonography in dogs with hyperlipidemia

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Evaluation of gallbladder motility assessed by ultrasonography in dogs with hyperlipidemia

Jessica A. Villm et al · Oxford University Press · 2023 · ISSN 0891-6640

Abstract Background The pathogenesis of gallbladder (GB) mucoceles in dogs is unknown. It has been proposed that hyperlipidemia could impair GB motility and contribute to GB mucocele formation. Hypothesis/Objectives The ...

LCC TENDOlZldGVyaW5hcnkgbWVkaWNpbmU~Idioma eng

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Evaluation of the congenital absence of the vas deferens with magnetic resonance imaging: preliminary findings

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Evaluation of the congenital absence of the vas deferens with magnetic resonance imaging: preliminary findings

Hakan İmamoğlu et al · Turkish Society of Radiology · 2026 · ISSN 1305-3825

PURPOSE: To date, no study provides definitive evidence for the pathogenesis of congenital absence of the vas deferens (CAVD). This study aims to evaluate the vas deferens (VD), particularly the intra-abdominal part and ...

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Expression of osteogenic proteins in kidneys of cats with nephrocalcinosis

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Expression of osteogenic proteins in kidneys of cats with nephrocalcinosis

Nuttha Hengtrakul et al · Oxford University Press · 2025 · ISSN 0891-6640

Abstract Background Nephrocalcinosis is a common pathological finding in cats with chronic kidney disease and nephrolithiasis. Understanding its pathogenesis may identify future therapeutic targets. Hypothesis Nephrocalc...

LCC TENDOlZldGVyaW5hcnkgbWVkaWNpbmU~Idioma eng

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FEATURES OF OUR PATIENTS WITH PRIMARY GLOMERULONEPHRITIS

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FEATURES OF OUR PATIENTS WITH PRIMARY GLOMERULONEPHRITIS

Mehmet Rıza ALTIPARMAK et al · Turkish Society of Nephrology · 2019 · ISSN 2667-4440

The distribution of the types of primary glomerulonephritis (GN) varies from one center to another depending on ethnicity, geographical region and the indication for biopsy. It was observed that the most frequent diagnos...

LCC LCC:Internal medicine; TENDOlBlZGlhdHJpY3M~Idioma eng

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Feline morbillivirus infection associated with fatal encephalitis in a Bengal cat

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Feline morbillivirus infection associated with fatal encephalitis in a Bengal cat

Kara L. D. Dawson et al · Oxford University Press · 2023 · ISSN 0891-6640

Abstract Feline morbillivirus (FeMV) is a recently discovered morbillivirus of the family Paramyxoviridae, which include several highly contagious viruses with zoonotic potential. In this case report we describe the dete...

LCC TENDOlZldGVyaW5hcnkgbWVkaWNpbmU~Idioma eng

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Ferritin and transferrin predict common carotid intima-media thickness in females: a machine-learning informed individual participant data meta-analysis

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Ferritin and transferrin predict common carotid intima-media thickness in females: a machine-learning informed individual participant data meta-analysis

Anand Ruban Agarvas et al · BMC · 2026 · ISSN 1471-2261

Abstract Background Iron overload promotes atherosclerosis in mice and causes vascular dysfunction in humans with Hemochromatosis. However, data are controversial on whether systemic iron availability within physiologica...

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Fungi in the respiratory tract of horses with recurrent airway obstruction

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Fungi in the respiratory tract of horses with recurrent airway obstruction

M.O. Xavier et al · Universidade Federal de Minas Gerais, Escola de Veterinária · 2014 · ISSN 1678-4162

This study aims to compare the concentration of viable fungi, especially those of the genus Aspergillus in the respiratory tract of stabled horses with and without Recurrent Airway Obstruction (RAO). Thirty two housed ho...

LCC LCC:Animal cultureIdioma eng

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Human cytomegalovirus gene expression in long-term infected glioma stem cells.

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Human cytomegalovirus gene expression in long-term infected glioma stem cells.

Estefania Fiallos et al · Public Library of Science (PLoS) · 2014 · ISSN 1932-6203

The most common adult primary brain tumor, glioblastoma (GBM), is characterized by fifteen months median patient survival and has no clear etiology. We and others have identified the presence of human cytomegalovirus (HC...

LCC LCC:Medicine; TENDOlNjaWVuY2U~Idioma eng

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Identification of a telomere-aging-related gene as a novel prognostic factor for intrahepatic cholangiocarcinoma: Machine learning-aided biomarker discovery and experimental verification

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Identification of a telomere-aging-related gene as a novel prognostic factor for intrahepatic cholangiocarcinoma: Machine learning-aided biomarker discovery and experimental verification

Jianjian Yin et al · Elsevier · 2026 · ISSN 2472-6303

Background: Intrahepatic cholangiocarcinoma (ICC) is an aggressive hepatobiliary malignancy characterized by a complex pathogenesis and poor prognosis. Telomere dysfunction and cellular senescence are involved in the pat...

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Identification of characteristic hub genes in the immune-active phase of chronic hepatitis B

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Identification of characteristic hub genes in the immune-active phase of chronic hepatitis B

Fangfang Li et al · Frontiers Media S.A · 2026 · ISSN 1664-3224

BackgroundChronic hepatitis B (CHB) caused by the hepatitis B virus (HBV) remains a major global health burden. The immune-active (IA) phase, characterized by positive Hepatitis B surface antigens (HBsAg), elevated alani...

LCC LCC:Immunologic diseases. AllergyIdioma eng

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In silico-guided drug repurposing: identification of non-competitive inhibitors of Trypanosoma cruzi and Plasmodium falciparum cysteine proteases

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In silico-guided drug repurposing: identification of non-competitive inhibitors of Trypanosoma cruzi and Plasmodium falciparum cysteine proteases

Salas Sarduy, Emir et al · Fundación Revista Medicina · 2020 · ISSN 0025-7680

Abstract/Resumen: Trypanosoma cruzi and Plasmodium falciparum are the etiologic agents of Chagas disease and Malaria, respectively. Cysteine proteases play key roles in the pathogenesis and survival of these parasites, s...

Idioma eng

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Inflammation as a Risk Factor for Carotid IntimalMedial Thickening, a Measure of Subclinical Atherosclerosis in Hemodialysis Patients and the Role of Chlamydia and Cytomegalovirus Infection

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Inflammation as a Risk Factor for Carotid IntimalMedial Thickening, a Measure of Subclinical Atherosclerosis in Hemodialysis Patients and the Role of Chlamydia and Cytomegalovirus Infection

Celalettin USALAN et al · Turkish Society of Nephrology · 2019 · ISSN 2667-4440

OBJECTIVE: Atherosclerotic vascular disease (AVD) is the most frequent complication seen in hemodialysis (HD) patients. Evidence suggests that inflammation may play a role in the pathogenesis and progression of atheroscl...

LCC LCC:Internal medicine; TENDOlBlZGlhdHJpY3M~Idioma eng

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Leczenie miejscowe trądziku

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Leczenie miejscowe trądziku

Waldemar Placek et al · Termedia Publishing House · 2011 · ISSN 0033-2526

Acne vulgaris is a common disease of adolescence that occurs in approximately80% of the population aged 11-30 years. The disease greatlyreduces well-being and self-esteem. In the pathogenesis of acne vulgarismany factors...

LCC LCC:Medicine; LCC:DermatologyIdioma eng

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Leishmania (Leishmania)hertigi in a porcupine (Coendou sp.) found in Brasília, Federal District, Brazil

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Leishmania (Leishmania)hertigi in a porcupine (Coendou sp.) found in Brasília, Federal District, Brazil

Denise Amaro da Silva et al · Colégio Brasileiro de Parasitologia Veterinária · ISSN 1984-2961

Studies report the occurrence of Leishmania(Leishmania) hertigi in northern states of Brazil. In the present investigation, we describe the isolation ofL. (L.) hertigi from a porcupine (Coendou sp.) found in Brasília, F...

LCC LCC:Animal cultureIdioma eng

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Loss of VMP1 Impairs Tight Junction Recycling and Aggravates Intestinal Barrier Dysfunction in Inflammatory Bowel Disease

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Loss of VMP1 Impairs Tight Junction Recycling and Aggravates Intestinal Barrier Dysfunction in Inflammatory Bowel Disease

Jiawei Zhao et al · Wiley · 2026 · ISSN 2198-3844

ABSTRACT Inflammatory bowel disease (IBD) is a chronic and relapsing inflammatory disorder of the gastrointestinal tract. This disease is characterized by a steadily increasing global incidence. Multiple susceptibility g...

LCC TENDOlNjaWVuY2U~Idioma eng

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