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Hypomorphic SCID Due to LIG4 Deficiency Not Detected on Newborn Screening
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Hypomorphic SCID Due to LIG4 Deficiency Not Detected on Newborn Screening
Layla Samandi et al · Rockefeller University Press · 2026 · ISSN 3065-8993
DNA ligase IV (LIG4) is essential for repairing breaks in double-stranded DNA via nonhomologous end-joining in developing lymphocytes and is particularly important for V(D)J recombination. First described in the early 20...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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IRF4 p.T95R Combined Immunodeficiency: Clinical Features and Transplant Outcomes
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IRF4 p.T95R Combined Immunodeficiency: Clinical Features and Transplant Outcomes
Mattison P. Stojcic et al · Rockefeller University Press · 2026 · ISSN 3065-8993
IntroductionInborn errors of interferon response factors (IRFs) are a subset of monogenic inborn errors of immunity, occurring as a result of damaging variants in the IRF genes. Of these diseases, IRF4 deficiencies are a...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Idiopathic Combined Immunodeficiency Associated with Primary Pulmonary Sporotrichosis
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Idiopathic Combined Immunodeficiency Associated with Primary Pulmonary Sporotrichosis
Marija Rowane et al · Rockefeller University Press · 2026 · ISSN 3065-8993
IntroductionSporotrichosis is an uncommon but emerging opportunistic infection in immunocompromised patients. Primary pulmonary sporotrichosis can disseminate and result in significant morbidity and mortality, despite tr...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Impact of Nirsevimab on Pediatric RSV-Related Lower Respiratory Tract Infections: A Retrospective Pre–Post Observational Study in Tuscany, Italy
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Impact of Nirsevimab on Pediatric RSV-Related Lower Respiratory Tract Infections: A Retrospective Pre–Post Observational Study in Tuscany, Italy
Francesco Nieddu et al · Adis, Springer Healthcare · 2026 · ISSN 2193-8229
Abstract Introduction Respiratory syncytial virus (RSV) is the leading cause of respiratory infections and hospitalization among infants and a major burden on pediatric emergency department (EDs). Nirsevimab has recently...
LCC TENDOkluZmVjdGlvdXMgYW5kIHBhcmFzaXRpYyBkaXNlYXNlcw~~Idioma eng
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Incidence of Voriconazole-induced periostitis in a tertiary medical center: a single-center retrospective analysis
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Incidence of Voriconazole-induced periostitis in a tertiary medical center: a single-center retrospective analysis
Boris Sokolovski et al · BMC · 2026 · ISSN 1471-2334
Abstract Objective Voriconazole is a commonly used antifungal medication, particularly for treating invasive pulmonary aspergillosis and as prophylaxis in hematologic malignancies. However, it can cause adverse effects, ...
LCC TENDOkluZmVjdGlvdXMgYW5kIHBhcmFzaXRpYyBkaXNlYXNlcw~~Idioma eng
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Incidence, survival, and risk factors for first-line antiretroviral therapy failure among adults on ART follow-up in health facilities in Southwest Shoa, Oromia, Ethiopia, 2023: a retrospective cohort study
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Incidence, survival, and risk factors for first-line antiretroviral therapy failure among adults on ART follow-up in health facilities in Southwest Shoa, Oromia, Ethiopia, 2023: a retrospective cohort study
Setegn Gemechu et al · BMC · 2026 · ISSN 1471-2334
Abstract Background The inability of antiretroviral medications to inhibit HIV is known as antiretroviral treatment failure. One of the greatest problems facing HIV patients receiving antiretroviral therapy is treatment ...
LCC TENDOkluZmVjdGlvdXMgYW5kIHBhcmFzaXRpYyBkaXNlYXNlcw~~Idioma eng
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Infecção urinária na gravidez Urinary tract infection in pregnancy
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Infecção urinária na gravidez Urinary tract infection in pregnancy
Geraldo Duarte et al · Federação Brasileira das Sociedades de Ginecologia e Obstetrícia · 2008 · ISSN 0100-7203
Vários fatores tornam a infecção do trato urinário (ITU) uma relevante complicação do período gestacional, agravando tanto o prognóstico materno quanto o prognóstico perinatal. Durante muitos anos, a gravidez fo...
LCC TENDOkd5bmVjb2xvZ3kgYW5kIG9ic3RldHJpY3M~Idioma eng
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Knowledge, Attitude, and Practices Towards Hepatitis B Infection Among Nursing Students: A Cross‐Sectional Study in Jordan
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Knowledge, Attitude, and Practices Towards Hepatitis B Infection Among Nursing Students: A Cross‐Sectional Study in Jordan
Nader Alaridah et al · Wiley · 2026 · ISSN 2398-8835
ABSTRACT Background and Aims Hepatitis B is a serious, communicable liver disease resulting from hepatitis B virus infection. Healthcare workers (HCWs), including nursing students, are at elevated risk of exposure. We as...
LCC LCC:MedicineIdioma eng
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Learning From Loss: Early Identification of ADA-SCID After Sibling Mortality
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Learning From Loss: Early Identification of ADA-SCID After Sibling Mortality
Amal Farooq et al · Rockefeller University Press · 2026 · ISSN 3065-8993
IntroductionAdenosine deaminase–deficient severe combined immunodeficiency (ADA-SCID) is an autosomal recessive disorder comprising ∼15% of SCID cases. Newborn screening (NBS) relies on T cell receptor excision circl...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Long-term outcomes and bleeding risk factors in pancreatic portal hypertension: a retrospective cohort study
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Long-term outcomes and bleeding risk factors in pancreatic portal hypertension: a retrospective cohort study
Yingjie Zhang et al · BMC · 2026 · ISSN 1471-230X
Abstract Background Pancreatic portal hypertension (PPH) is a distinct form of sinistral (left-sided) portal hypertension, primarily resulting from pancreatic diseases such as acute or chronic pancreatitis and pancreatic...
LCC LCC:Diseases of the digestive system. GastroenterologyIdioma eng
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MARRIAGES, PREGNANCIES AND PARENTHOODS DURING POSTTRANSPLANTATION PERIOD
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MARRIAGES, PREGNANCIES AND PARENTHOODS DURING POSTTRANSPLANTATION PERIOD
Seyit Mehmet KAYACAN et al · Turkish Society of Nephrology · 2019 · ISSN 2667-4440
Psychiatric and social rehabilitation is also very important as well as the medical rehabilitation after a successful transplantation. Encouragement of both marriage of single or widowed patients and becoming a parent of...
LCC LCC:Internal medicine; TENDOlBlZGlhdHJpY3M~Idioma eng
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Maternal and Perinatal Outcomes of Pregnancies Complicated by Chronic Hypertension Followed at a Referral Hospital
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Maternal and Perinatal Outcomes of Pregnancies Complicated by Chronic Hypertension Followed at a Referral Hospital
Gabriela Pravatta Rezende et al · Federação Brasileira das Sociedades de Ginecologia e Obstetrícia · 2020 · ISSN 0100-7203
Abstract Objective To assess maternal and perinatal outcomes of pregnancies in women with chronic hypertension (CH). Methods Retrospective cohort of women with CH followed at a referral center for a 5 year period (2012-...
LCC TENDOkd5bmVjb2xvZ3kgYW5kIG9ic3RldHJpY3M~Idioma eng
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Multiple Bouts of Hypothermia and Shock in a Child with Gata-2 Mutation
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Multiple Bouts of Hypothermia and Shock in a Child with Gata-2 Mutation
Kristin Hanscom et al · Rockefeller University Press · 2026 · ISSN 3065-8993
We are reporting a 14-year-old male who presented at 12 years of age with recurrent episodes of hypothermia and bradycardia (30s) secondary to culture-negative septic shock from presumed viral respiratory illnesses. His ...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Novel FOXN1 Variant as Cause of Neonatal T Cell Lymphopenia
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Novel FOXN1 Variant as Cause of Neonatal T Cell Lymphopenia
Sonia Joshi et al · Rockefeller University Press · 2026 · ISSN 3065-8993
In the last decade, diagnostic detection of severe combined immune deficiency (SCID) has improved with the widespread implementation of universal newborn screening (NBS) for SCID in the United States. Our case identifies...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Porque usamos imunoglobulina anti-D em excesso no abortamento precoce? Why do we waste anti-D immunoglobulin in early miscarriage?
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Porque usamos imunoglobulina anti-D em excesso no abortamento precoce? Why do we waste anti-D immunoglobulin in early miscarriage?
Eduardo Baiochi et al · Federação Brasileira das Sociedades de Ginecologia e Obstetrícia · 2004 · ISSN 0100-7203
OBJETIVO: avaliação da hemorragia feto-materna (HFM) nas pacientes que receberiam profilaxia da aloimunização Rh com emprego de imunoglobulina anti-D (300 mig), pós-aborto precoce. MÉTODO: foram admitidas no estudo...
LCC TENDOkd5bmVjb2xvZ3kgYW5kIG9ic3RldHJpY3M~Idioma eng
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Prevalence and Risk Factors of Anemia in Pregnant Women Attending Antenatal Clinic at a Medical Center in Accra, Ghana: A Cross‐Sectional Study
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Prevalence and Risk Factors of Anemia in Pregnant Women Attending Antenatal Clinic at a Medical Center in Accra, Ghana: A Cross‐Sectional Study
Gifty Amewudah et al · Wiley · 2026 · ISSN 2398-8835
ABSTRACT Background Anemia during pregnancy remains a major cause of maternal and infant morbidity in Ghana and has broader socioeconomic implications. Its persistence despite existing interventions indicates that factor...
LCC LCC:MedicineIdioma eng
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Preventive strategies for needle stick incidents during surgical procedures: a narrative review to guide healthcare professionals
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Preventive strategies for needle stick incidents during surgical procedures: a narrative review to guide healthcare professionals
Collen Sandile Nkosi et al · Elsevier · 2026 · ISSN 2773-157X
Needlestick injuries (NSI) result from penetrating trauma or lacerations to the skin. This includes needles, cannulae, needles utilized for connecting components of intravenous administration systems, and surgical equipm...
LCC TENDOk9ydGhvcGVkaWMgc3VyZ2VyeQ~~Idioma eng
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Prospective Clinical Trial of Mycophenolate Mofetil (MMF) Duration De-Escalation in Allogeneic Hematopoietic Cell Transplantation (HCT) for Inborn Errors of Immunity: Is MMF Dispensable After Reduced Intensity Conditioning, Posttransplantation Cyclophosphamide(Ptcy)-Based HCT?
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Prospective Clinical Trial of Mycophenolate Mofetil (MMF) Duration De-Escalation in Allogeneic Hematopoietic Cell Transplantation (HCT) for Inborn Errors of Immunity: Is MMF Dispensable After Reduced Intensity Conditioning, Posttransplantation Cyclophosphamide(Ptcy)-Based HCT?
Dimana Dimitrova et al · Rockefeller University Press · 2026 · ISSN 3065-8993
Hematopoietic cell transplantation (HCT) offers curative potential for inborn errors of immunity (IEI) patients, who often enter HCT with significant comorbidities and disease sequelae, active infections, and/or limited ...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Recommendations from guidelines for the prevention of venous thromboembolism in pregnant women with inherited thrombophilia
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Recommendations from guidelines for the prevention of venous thromboembolism in pregnant women with inherited thrombophilia
Werner Rath et al · Springer · 2026 · ISSN 1432-0711
Abstract Women with inherited thrombophilia represent more than 15% of the pregnant population. 20–50% of pregnancy-related venous thromboembolism (VTE) is associated with at least one inherited thrombophilia, which in...
LCC TENDOkd5bmVjb2xvZ3kgYW5kIG9ic3RldHJpY3M~Idioma eng
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STAT1 Gain-of-Function with a Novel Clinical Manifestation: Recurrent Pancreatitis Associated with Hypertriglyceridemia and Anti-GPIHBP1 Autoantibodies
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STAT1 Gain-of-Function with a Novel Clinical Manifestation: Recurrent Pancreatitis Associated with Hypertriglyceridemia and Anti-GPIHBP1 Autoantibodies
Areum Shin et al · Rockefeller University Press · 2026 · ISSN 3065-8993
Patients with STAT1 gain-of-function (GOF) variants may present not only with chronic mucocutaneous candidiasis and other forms of immunodeficiency but also with a broad-spectrum of autoimmune manifestations, for which J...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Seroprevalence of Toxoplasmosis in Puerperal Women Treated at a Tertiary Referral Hospital
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Seroprevalence of Toxoplasmosis in Puerperal Women Treated at a Tertiary Referral Hospital
Juliana Fernandes Medeiros et al · Federação Brasileira das Sociedades de Ginecologia e Obstetrícia · 2023 · ISSN 0100-7203
Abstract Objective To evaluate the seroprevalence of toxoplasmosis among puerperal women cared for at a tertiary university hospital and the level of understanding of these puerperal women about toxoplasmosis, vertical ...
LCC TENDOkd5bmVjb2xvZ3kgYW5kIG9ic3RldHJpY3M~Idioma eng
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Successful Allogeneic Hematopoietic Cell Transplantation in Two Patients with IL-12Rβ1 Deficiency
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Successful Allogeneic Hematopoietic Cell Transplantation in Two Patients with IL-12Rβ1 Deficiency
Alexandra Freeman et al · Rockefeller University Press · 2026 · ISSN 3065-8993
IL-12Rβ1 deficiency is thought to be the most common etiology of Mendelian susceptibility to mycobacterial disease with incomplete penetrance and variable expressivity. Allogeneic hematopoietic cell transplantation (HCT...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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THE EFFICACY AND SAFETY OF SANDIMMUN NEORAL IN NEW TRANSPLANT PATIENTS
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THE EFFICACY AND SAFETY OF SANDIMMUN NEORAL IN NEW TRANSPLANT PATIENTS
Abdülkadir ÜNSAL et al · Turkish Society of Nephrology · 2019 · ISSN 2667-4440
A new microemulsion formula (Sandimmun Neoral: SIM-NO) was developed to solve the problem of variable absorption and lower bioavailability of conventional Sandimmune (SIM), showed 74 to 139% better bioavailability, and w...
LCC LCC:Internal medicine; TENDOlBlZGlhdHJpY3M~Idioma eng
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The International/Canadian hereditary angioedema guideline
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The International/Canadian hereditary angioedema guideline
Stephen Betschel et al · BMC · 2026 · ISSN 1710-1492
Abstract This update to the 2019 Canadian Hereditary Angioedema (HAE) Guideline broadens its focus to include the management of patients with HAE worldwide, building on its established international framework. It has bee...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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