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Ferrochelatases catalyze the insertion of ferrous iron into the porphyrin during the heme b biosynthesis pathway, which is fundamental for both prokaryotes and eukaryotes. Interestingly, in the active site of ferrochelat...

We study the intermittency properties of the energy and helicity cascades in two 15363 direct numerical simulations of helical rotating turbulence. Symmetric and antisymmetric velocity increments are examinedas well as p...

Traditional electromechanical cleaning equipment remains overly dependent on human assistance when performing cleaning tasks in unstructured marine environments. With the rapid development of robotic technologies, underw...

A novel full-atom multiscale method, combining different computational approaches and aimed to describe diffusion of multiple ions in anion exchange membranes (AEM), is presented. The method is used to evaluate diffusion...

We study the role of group infall in the assembly and dynamics of galaxy clusters in ΛCDM. We select 10 clusters with virial mass M200 ∼1014 M from the cosmological hydrodynamical simulation Illustris and follow their...

UDP-glucose:glycoprotein glucosyltransferase (UGGT) flags misfolded glycoproteins for ER retention. We report crystal structures of full-length Chaetomium thermophilum UGGT (CtUGGT), two CtUGGT double-cysteine mutants, a...

Abstract Given the escalating challenges of water scarcity and climate change, enhancing water productivity is crucial for achieving water security, particularly in arid regions with finite water resources. This study as...

Hydrogen is widely recognized as a clean and sustainable energy carrier, driving the urgent need for safe and efficient solid-state storage materials. In this study, the structural, thermodynamic, electronic, optical, an...

Farnesyl diphosphate synthase from Geobacillus stearothermophilus (GsFPPS) is a thermophilic enzyme which belongs to the prenyltransferase family. We found that the point mutation of an amino acid located on the fifth po...

Rapid climatic changes and increasing human influence at high elevations around the world will have profound impacts on mountain biodiversity. However, forecasts from statistical models (e.g. species distribution models)...

Rational protein design has successfully enhanced the mechanical stability of biomaterials by optimizing the internal topology of force-bearing domains. However, current design strategies predominantly focus on isolated ...

Due to its complexity, corruption tolerance among public servants has predominantly been investigated through qualitative rather than quantitative research. Accordingly, this article examines tolerance of public corrupti...

This study investigates the capability of two-dimensional Computational Fluid Dynamics (CFD) simulation to estimate the temperature distribution pattern and velocity contours in a single slope solar still that uses soybe...

Placing a material inside an optical cavity can enhance transport of excitation energy by hybridizing excitons with confined light modes into polaritons, which have a dispersion that provides these light–matter quasi-p...

Abstract In order to address health monitoring issues on offshore wind turbines, while taking into account engineering know-how and constraints, we propose a robust model identification procedure based on reliability of ...

We present an overview of the Middle Ages Galaxy Properties with Integral Field Spectroscopy (MAGPI) survey, a Large Program on the European Southern Observatory Very Large Telescope. MAGPI is designed to study the physi...

We report the synthesis, structural characterization, and atomistic simulations of AgPd-Pt trimetallic (TM) nanoparticles. Two types of structure were synthesized using a relatively facile chemical method: multiply twinn...

Abstract Background and objectives Squamous cell carcinoma antigen recognized by T-cells 3 (SART3) has emerged as a promising target for cancer immunotherapy, given its overexpression in various malignancies and low or a...

The increasing penetration of renewable energy sources (RES) reduces power system inertia, causing severe frequency excursions following disturbances. Conventional Automatic Generation Control (AGC) using fixed-gain cont...

Indoor air quality is a crucial factor that directly impacts worker safety and health (K3), where exposure to hazardous pollutants such as formaldehyde can trigger irritation, respiratory disorders, and long-term health ...

Introduction. Self-excited induction generators (SEIGs) play a vital role in renewable energy systems, particularly in remote regions. However, their performance is highly sensitive to excitation capacitance, rotor speed...

IntroductionVision-based fall analysis has advanced rapidly, yet a key bottleneck remains: visually similar motions can correspond to markedly different physical outcomes, as subtle differences in contact mechanics and p...

Abstract Background and purpose Claudin-5 plays a crucial role in maintaining blood-brain barrier (BBB) integrity through endothelial tight junction formation. Alternative splicing of claudin-5 within the microvascular e...

Introduction. The stability of grid-connected inverters is critical for the integration of renewable energy into modern power systems. However, this stability is significantly challenged under weak grid conditions, chara...