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Tingting Huang,1 Jibao Qin,2 Xi Jiang,1 Ming Hu,1 Jiaping Wang,1 Kaiyong Chen,3 Fumeng Yang,4 Jin Gu,5 Huiyi Wu,1 Xinkuan Chen6 1Department of Laboratory Medicine, Donghai Hospital Affiliated to Kangda College of Nanjing...

Acute heart failure (AHF) requires immediate intervention, with diuretics central to managing volume overload. We conducted a prospective single-arm study to explore changes in diuretic and renal outcomes following initi...

Abstract Stigmatization and discrimination toward people living with HIV/AIDS (PLWHA) continue to be significant hurdles to successful treatment and social integration, especially in Nigeria. These barriers have a negati...

Abstract Background Adoptive cell therapy with tumour-infiltrating lymphocytes has been recognised as a safe and effective treatment for patients with advanced melanoma. Whether such a novel intervention is cost-effectiv...

BackgroundStroke remains a primary cause of long-term disability worldwide, with upper-limb deficits affecting up to 80% of survivors acutely and 40% chronically. These deficits lead to considerable effects on their inde...

Abstract Background Clinical responses to mesenchymal stromal cell (MSC) therapies remain variable because MSCs are often treated as uniform biologics despite donor-programmed differences. Evidence indicates that develop...

Abstract Introduction The majority of human immunodeficiency virus (HIV), hepatitis B virus (HBV) and hepatitis C virus (HCV) infection diagnoses in France involve migrant populations, who face challenges in navigating...

Theeran Gill, Guo Hou Loo, Guhan Muthkumaran, Nik Ritza Kosai Upper GI & Metabolic Surgery Unit, Department of Surgery, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, MalaysiaCorrespondence: Guo H...

ABSTRACT Respiratory diseases have a major impact on sport horses and are often cited as the second most common reason for loss of training days and significant veterinary costs. Adult horses most commonly develop pneumo...

The prevalence of diabetes mellitus in China has increased from

Background: Embryonic stem (ES) cells have the potential to produce unlimited numbers of surrogate insulin-producing cells for cell replacement therapy of type 1 diabetes mellitus. The impact of the in vivo environment o...

Abstract Background Sarcomas comprise a heterogeneous group of aggressive mesenchymal malignancies with limited therapeutic options and poor prognosis, underscoring the need for novel treatment strategies. Fibroblast act...

Abstract Introduction: The Psychotherapy Process Q-Set (PQS) prototype method is used to measure the extent to which ideal processes of different psychotherapies are present in real cases, allowing researchers to exami...

HER2-low breast cancer, defined as immunohistochemistry (IHC) 1+ or 2+ with negative in situ hybridization (ISH), has emerged as a clinically relevant therapeutic subgroup. We report the case of a 40-year-old woman with ...

Abstract Therapeutic resistance remains a major cause of treatment failure and disease recurrence across cancer types, considerably limiting the long-term efficacy of chemotherapies, targeted therapies, and immunotherapi...

Abstract Background Malnutrition among hospitalized older adults in the United States is a growing public health concern associated with poor quality of life, increased mortality, higher readmission rates, and loss of in...

Growing evidence underscores the importance of hope in shaping patients’ experiences. In the context of illness, hope regulates emotions, supports resilience, helps patients face uncertainty, and sustains the belief th...

PurposeThe COVID-19 pandemic disrupted essential services, posing unique challenges for individuals with Autism Spectrum Disorder (ASD) who depend on consistent, specialized support. Service providers faced unique challe...

We evaluated whether the lack of TNF-α signaling increases mucosal levels of annexin A1 (AnxA1); the hypothesis stems from previous findings showing that TNF-α neutralization in Crohn´s disease patients up-regulates s...

Bashir Dahir Ahmed,1 Mohamed Hassan Mohamud,2 Omar Sidow Zubair,3 Mohamed Abdi Warsame,4 Tigad Abdisad Ali5 1Department of Orthopedics, Madina Hospital, Mogadishu, Somalia; 2Faculty of Medicine and Surgery, Zamzam Univer...

Enterocutaneous fistulas (ECFs) are among the most devastating complications in surgical practice. Management requires a multidisciplinary approach focused on sepsis control, nutritional optimization, fistula closure, an...

Abstract Background Stage III non-small cell lung cancer (NSCLC) is heterogeneous and poses significant treatment challenges. In recent years, neoadjuvant therapy has emerged as a promising treatment strategy for patient...

Background: Glenohumeral osteoarthritis (GHOA) is a common cause of impaired lifestyle, quality of life, and emotional well-being. Despite its frequency, there is insufficient evidence to recommend specific management st...

Jiayin Chen,* Zhuochao Li,* Xun Qi Key Laboratory of DiagnosticImaging and Interventional Radiology of Liaoning Province, Department of Interventional Therapy, The First Hospital of China Medical Universi...