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Abstract Cartilage and synovium are essential tissues involved in joint-related diseases and traits, including osteoarthritis (OA), rheumatoid arthritis (RA), and human height. Although genome-wide association studies (G...

Unlike their normal counterparts, tumor cells exhibited highly variable CpG methylation levels in a large proportion of the genome, which can lead to malignant cell transformation through multiple pathways. This prompted...

ABSTRACT In women, high-definition ultrasonography provides high-quality images of normal and diseased tissues throughout pregnancy, however there are no veterinary studies describing the use of this technology in pregna...

Dihydroxychalcones as well as other metabolites synthesized via the phenylpropanoid pathway have a wide range of biological activities. Although this class of phenolic compounds is found in very large amounts in some tis...

Abstract Background To improve the visualisation of colorectal cancer (CRC) and its metastatic lymph nodes (LNs), we developed a second near-infrared window (NIR-II; 1000–1700 nm) fluorescent probe using a monoclonal ...

Abstract Objective This study aimed to systematically identify and validate KIF15 as a potential diagnostic and prognostic biomarker in colon cancer (CC) using integrated bioinformatics analyses. We further explored its ...

Abstract Papillary Thyroid Cancer (PTC) is one of the most prevalent endocrine malignancies, and its incidence rate has almost tripled over the past three decades. The current study aimed to identify gene alterations and...

Orf virus causes infections in sheep and goats with lesions especially around muzzle and mouth. The disease is widespread, and most sheep-rearing countries are not free of infection. Disease is caused by ORF virus (ORFV)...

ABSTRACT Mycoplasma bovis is a highly infectious pathogenic microorganism that causes various clinical signs in cattle, including pneumonia, arthritis, and mastitis, often resulting in significant economic losses. The ad...

A 5-month (2005) study was conducted in Argentina to determine the effect of food-grade antioxidants (butylated hydroxyanisole [BHA], butylated hydroxytoluene [BHT] and propyl paraben [PP]) alone and in mixtures on funga...

Electrospinning is a technique that allows the preparation of nanofibers from various materials. Chitosan is a natural and abundant easily obtained polymer, which, in addition to those features, proved to be biocompatibl...

Gibberellic acid (GA3) is the most widely used plant growth regulator to thin out bunches and increase berry size in seedless table grapes, but there is evidence of its negative effects, including loss of fertility and m...

Agricultural drainage carrying significant amounts of nitrogen (N) from agricultural applications poses a significant threat to plant growth, composition, and structure in wetland ecosystems. However, how interspecific c...

Latar Belakang: Pada kondisi fisiologis, gigi geligi berada pada posisi stabil dalam lengkung rahang, mempunyai kontak oklusal dengan gigi lawan, dan kontak proksimal dengan gigi disebelahnya. Adanya sedikit pembukaan ko...

Abstract Angiogenesis and its maturation play a crucial role in the progression and prognosis of head and neck squamous cell carcinoma (HNSCC). Tumor growth relies on an adequate blood supply to meet metabolic demands, w...

Encapsulation-dehydration, encapsulation-vitrification, and vitrification were tested for cryopreservation of Lotus tenuis (Fagaceae) adventitious buds clusters (ABCs) obtained by a direct regeneration system from leaves...

Abstract Background Immune tolerance breakdown at the maternal-fetal interface is implicated in unexplained recurrent pregnancy loss (URPL), but the interplay between T cell hyperactivation and dendritic cells (DCs)-medi...

Introduction and aims: Increasing evidence suggests that marginal zone B and B1 cell-specific protein (MZB1) plays crucial roles in inflammatory responses, endoplasmic reticulum (ER) stress, and cell survival, but its fu...

Leishmaniasis is a zoonotic disease that affects 12 million people worldwide. Several mammalian species can serve as a reservoir for this disease. Dogs are the main reservoir for visceral leishmaniasis in urban areas, wh...

Abstract Background Congenital anomalies of the kidney and urinary tract (CAKUT) comprise a heterogeneous group of developmental disorders with diverse genetic etiologies. However, it remains unclear whether these geneti...

BackgroundAutoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) is an inborn error of immunity caused by loss-of-function of the AIRE gene. Lack of AIRE impairs thymic negative selection of T cells, cau...

ABSTRACT Healthcare systems are progressively shifting toward long‐term, personalized models that rely on continuous physiological monitoring, thereby intensifying the need for advanced bioelectronic technologies. The ...

Abstract Background Tauopathies are a group of neurodegenerative diseases, including Alzheimer’s disease (AD), characterized by progressive accumulation of pathological Tau proteins. Among the diverse Tau species, trun...

Abstract Current treatment for atherosclerotic cardiovascular diseases (ASCVD) mainly focuses on the modification of systemic risk factors, such as hyperglycemia and hyperlipidemia. Despite significant efforts and expans...