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A Chlamydia trachomatis CPAF-STING agonist conjugate vaccine administered intramuscularly and intradermally is immunogenic in the pig model

ISSN: 16643224 · Editor / fuente: Frontiers Media

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An Atypical Case of X-Linked Agammaglobulinemia: A Male Child with a Pathogenic Variant in BTK with Preserved IgG and IgM Production and Responsiveness to Tetanus Vaccine
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An Atypical Case of X-Linked Agammaglobulinemia: A Male Child with a Pathogenic Variant in BTK with Preserved IgG and IgM Production and Responsiveness to Tetanus Vaccine
Nicole Soucy et al · Rockefeller University Press · 2026 · ISSN 3065-8993
BackgroundX-Linked agammaglobulinemia (XLA) is characterized by absent B cell development due to defects in the BTK gene. Patients with this condition have B cell aplasia as well as agammaglobulinemia and impaired vaccin...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Anti-SARS-CoV-2 response in alveolar blood sample and bronchoalveolar lavage fluid of individuals vaccinated with inactivated COVID-19 vaccines
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Anti-SARS-CoV-2 response in alveolar blood sample and bronchoalveolar lavage fluid of individuals vaccinated with inactivated COVID-19 vaccines
Yingwei Zhang et al · Taylor & Francis Group · 2026 · ISSN 2164-5515
Mucosal antibody response in lower respiratory tract to COVID-19 vaccines is less studied. This cross-sectional study evaluated the respiratory mucosal antibody response in subjects vaccinated with Aikewei or CoronaVac i...
LCC LCC:Immunologic diseases. Allergy; LCC:Therapeutics. PharmacologyIdioma eng
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Assessment of the Cultural Nuances in COVID-19 Vaccine Uptake Through a Comparative Analysis of English and Spanish Facebook Posts in Tarrant County, Texas: Longitudinal Study
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Assessment of the Cultural Nuances in COVID-19 Vaccine Uptake Through a Comparative Analysis of English and Spanish Facebook Posts in Tarrant County, Texas: Longitudinal Study
Ana Aleksandric et al · JMIR Publications · 2026 · ISSN 1947-2579
Abstract BackgroundPrior studies have identified key factors contributing to COVID-19 vaccine hesitancy, including concerns over vaccine safety, potential side effects, and mistrust in the health care system....
LCC LCC:Public aspects of medicine; TENDOkNvbXB1dGVyIGFwcGxpY2F0aW9ucyB0byBtZWRpY2luZS4gTWVkaWNhbCBpbmZvcm1hdGljcw~~Idioma eng
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Assessment of the acid phosphatase CP01850 from Corynebacterium pseudotuberculosis in DNA and subunit vaccine formulations against caseous lymphadenitis
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Assessment of the acid phosphatase CP01850 from Corynebacterium pseudotuberculosis in DNA and subunit vaccine formulations against caseous lymphadenitis
A.F.S. Rezende et al · Universidade Federal de Minas Gerais, Escola de Veterinária · ISSN 1678-4162
ABSTRACT The target cp1002_RS01850 from Corynebacterium pseudotuberculosis was used to construct a DNA and recombinant subunit vaccine against caseous lymphadenitis. Recombinant protein rCP01850 was expressed in Escheric...
LCC LCC:Animal cultureIdioma eng
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Comparable immunogenicity from murine blood collection methods in intranasal gonococcal vaccination with ACP and MtrE supports refinement of preclinical vaccine studies
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Comparable immunogenicity from murine blood collection methods in intranasal gonococcal vaccination with ACP and MtrE supports refinement of preclinical vaccine studies
Abhishek Chanda et al · Nature Portfolio · 2026 · ISSN 2045-2322
Abstract Preclinical vaccine studies often rely on antibody titers and functional assays to assess immunogenicity, but the impact of blood collection methods on these immunological outcomes remains poorly characterized. ...
LCC LCC:Medicine; TENDOlNjaWVuY2U~Idioma eng
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Depression, anxiety, and stress among adults in Kuwait across pre- and post-vaccine phases of the COVID-19 pandemic: a repeated cross-sectional study
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Depression, anxiety, and stress among adults in Kuwait across pre- and post-vaccine phases of the COVID-19 pandemic: a repeated cross-sectional study
Eiman Alawadhi et al · Frontiers Media S.A · 2026 · ISSN 2296-2565
BackgroundThe COVID-19 pandemic has significantly affected mental health globally, with important implications for pandemic preparedness, yet psychological responses across pandemic phases in the Gulf region remain under...
LCC LCC:Public aspects of medicineIdioma eng
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Development and evaluation of a novel subunit vaccine for Mycoplasma gallisepticum
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Development and evaluation of a novel subunit vaccine for Mycoplasma gallisepticum
L. Moura et al · Universidade Federal de Minas Gerais, Escola de Veterinária · 2012 · ISSN 1678-4162
Adhesion proteins from Mycoplasma gallisepticum (MG) encoded by cytadhesion genes mgc1 and mgc2 were cloned into plasmid vectors and transformed into E. coli. Seventeen groups of specific-pathogen free (SPF), birds at fo...
LCC LCC:Animal cultureIdioma eng
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Development of a Prophylactic mRNA Vaccine for Severe Fever with Thrombocytopenia Syndrome Using HSA based LNP
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Development of a Prophylactic mRNA Vaccine for Severe Fever with Thrombocytopenia Syndrome Using HSA based LNP
Tsenddari Ganbold et al · Nature Portfolio · 2026 · ISSN 2059-0105
Abstract Current lipid nanoparticles (LNPs) used in mRNA vaccines typically incorporate polyethylene glycol (PEG) as a stabilizing material; however, safety concerns have prompted the search for non-PEG alternatives. Sev...
LCC LCC:Immunologic diseases. Allergy; TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbIdioma eng
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Efficacy and safety of an oral live attenuated human rotavirus vaccine against rotavirus gastroenteritis during the first 2 years of life in Latin American infants: a randomised, double-blind, placebo-controlled phase III study
Artículo
Acceso abierto Artículo Universidad de Chile
Efficacy and safety of an oral live attenuated human rotavirus vaccine against rotavirus gastroenteritis during the first 2 years of life in Latin American infants: a randomised, double-blind, placebo-controlled phase III study
Linhares, Alexandre C. et al · ELSEVIER · 2010 · ISSN 1181-1189
Background Peak incidence of rotavirus gastroenteritis is seen in infants between 6 and 24 months of age. We therefore aimed to assess the 2-year efficacy and safety of an oral live attenuated human rotavirus vaccine for...
Idioma en
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Efficiency of inactive vaccines against contagious agalactia in Brazil
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Efficiency of inactive vaccines against contagious agalactia in Brazil
A.C. Campos et al · Universidade Federal de Minas Gerais, Escola de Veterinária · 2013 · ISSN 1678-4162
This paper aims to evaluate the efficiency of three inactive vaccines against contagious agalactia prepared with samples of Mycoplasma agalactiae isolated in Brazil and different adjuvants. Vaccine 1 adsorbed with alumin...
LCC LCC:Animal cultureIdioma eng
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Hope, health and cure: the meanings of the vaccine against COVID-19
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Hope, health and cure: the meanings of the vaccine against COVID-19
Cynthia de Freitas Melo et al · Universidade de São Francisco, Programa de Pós-Graduação Stricto Sensu em Psicologia · 2023 · ISSN 2175-3563
Abstract The objective of this study was to identify the meanings that Brazilians attribute to the vaccines against COVID-19. A non-probabilistic sample of 1,817 Brazilians was used, each of whom answered a sociodemograp...
LCC TENDOlBzeWNob2xvZ3k~Idioma eng
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Humane endpoint in mice by Brazilian researchers in the vaccine sector
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Humane endpoint in mice by Brazilian researchers in the vaccine sector
F.R.C. Araujo et al · Universidade Federal de Minas Gerais, Escola de Veterinária · ISSN 1678-4162
ABSTRACT The application of a humane endpoint (HE) for mice in vaccine trials and further challenging tasks with lethal samples is necessary to reduce or prevent pain and suffering in these animals, and is a refinement o...
LCC LCC:Animal cultureIdioma eng
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Latinx youth's and parents' covid-19 beliefs, vaccine hesitancy and vaccination rates: Longitudinal associations in a community sample.
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Latinx youth's and parents' covid-19 beliefs, vaccine hesitancy and vaccination rates: Longitudinal associations in a community sample.
Namoonga M Mantina et al · Public Library of Science (PLoS) · 2024 · ISSN 1932-6203
IntroductionThe Latinx population has the second highest COVID-19 death rate among racial/ethnic groups in the United States and less than half of Latinx youth aged 5-17 years old completed their COVID-19 primary vaccina...
LCC LCC:Medicine; TENDOlNjaWVuY2U~Idioma eng
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Molecular characterization of rabbit hemorrhagic disease virus type 2 and long-lasting protection conferred by a VLP-based vaccine
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Molecular characterization of rabbit hemorrhagic disease virus type 2 and long-lasting protection conferred by a VLP-based vaccine
Yanhui Wang et al · BMC · 2026 · ISSN 1746-6148
Abstract Background Rabbit hemorrhagic disease virus (RHDV) type 2 (GI.2) is an emerging pathogen genetically distinct from classic RHDV (GI.1). It can infect young, wild, and even vaccinated rabbits, and may also contra...
LCC TENDOlZldGVyaW5hcnkgbWVkaWNpbmU~Idioma eng
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PROTOCOL: Exploring education to support vaccine confidence amongst healthcare and long‐term care staff amidst the COVID‐19 pandemic: A protocol for a living scoping review
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PROTOCOL: Exploring education to support vaccine confidence amongst healthcare and long‐term care staff amidst the COVID‐19 pandemic: A protocol for a living scoping review
Anna C. Reed et al · SAGE Publishing · 2022 · ISSN 1891-1803
Abstract Despite the demonstrated effectiveness of vaccines, varying levels of hesitancy were observed among healthcare and long‐term care workers, who were prioritized in the roll out of COVID‐19 vaccines due to the...
LCC TENDOlNvY2lhbCBTY2llbmNlcw~~Idioma eng
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Perfil de restrição de um fragmento do gene da hemaglutinina amplificado pela RT-PCR a partir de estirpes vacinais e selvagens do vírus da cinomose canina Restriction pattern of a hemagglutinin gene amplified by RT-PCR from vaccine strains and wild-type canine distemper virus
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Perfil de restrição de um fragmento do gene da hemaglutinina amplificado pela RT-PCR a partir de estirpes vacinais e selvagens do vírus da cinomose canina Restriction pattern of a hemagglutinin gene amplified by RT-PCR from vaccine strains and wild-type canine distemper virus
F.J. Negrão et al · Universidade Federal de Minas Gerais, Escola de Veterinária · 2006 · ISSN 0102-0935
Fragmentos com 721 pares de bases do gene da hemaglutinina (H) do vírus da cinomose canina (CDV), amplificados pela RT-PCR a partir de três estirpes vacinais (Snyder Hill, Onderstepoort e Rockborn) e de 27 amostras de ...
LCC LCC:Animal cultureIdioma eng
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Prefusion-stabilized Hantaan virus glycoprotein nucleic acid vaccine elicits potent neutralizing antibody responses via germinal center activation
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Prefusion-stabilized Hantaan virus glycoprotein nucleic acid vaccine elicits potent neutralizing antibody responses via germinal center activation
Wei Ye et al · Nature Portfolio · 2026 · ISSN 2041-1723
Abstract Old World orthohantaviruses, including Hantaan virus (HTNV), cause hemorrhagic fever with renal syndrome (HFRS) in Eurasia. Available inactivated vaccines often induce low neutralizing antibodies and short-term ...
LCC TENDOlNjaWVuY2U~Idioma eng
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RESPONSIVENESS TO HEPATITIS B VACCINE IN HEMODIALYSIS, CAPD, AND PREDIALYSIS PATIENTS BY DOUBLING THE DOSE SCHEDULING
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RESPONSIVENESS TO HEPATITIS B VACCINE IN HEMODIALYSIS, CAPD, AND PREDIALYSIS PATIENTS BY DOUBLING THE DOSE SCHEDULING
Ayhan DOĞUKAN et al · Turkish Society of Nephrology · 2019 · ISSN 2667-4440
Hepatitis B vaccine is effective in producing protection against hepatitis B virus infection in uremic patients, but these patients respond less well than do the healthy. In this study, we vaccinated 29 hemodialysis pati...
LCC LCC:Internal medicine; TENDOlBlZGlhdHJpY3M~Idioma eng
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Results of the development of a vaccine against strangles in horses for Russia and Mongolia
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Results of the development of a vaccine against strangles in horses for Russia and Mongolia
M. Р. Neustroev et al · Federal Agricultural Research Center of the North-East named N.V. Rudnitsky · 2026 · ISSN 2072-9081
Equine strangles, a widespread infectious disease, poses a serious problem resulting in significant economic losses in the horse breeding industry. As there are no effective and safe methods for specific prevention of th...
LCC LCC:AgricultureIdioma rus
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Safety surveillance of respiratory syncytial virus (RSV) vaccine among pregnant individuals: a real-world pharmacovigilance study using the Vaccine Adverse Event Reporting System
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Safety surveillance of respiratory syncytial virus (RSV) vaccine among pregnant individuals: a real-world pharmacovigilance study using the Vaccine Adverse Event Reporting System
Alami, Abdallah et al · Wiley · 2025 · ISSN 2044-6055
Objectives: To describe the post-marketing safety profile of respiratory syncytial virus prefusion F (RSVpreF) vaccine among pregnant individuals.Design: This study analysed adverse event (AE) reports submitted to the U....
Idioma eng
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A new take on optimal vaccine prioritization: when age-based strategy is efficient?
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A new take on optimal vaccine prioritization: when age-based strategy is efficient?
Chaves Rêgo, Leandro et al · Springer Nature · 2026
"The rapid spread, high mortality rate, and hospital overcrowding made the SARS-CoV-2 virus a significant challenge for humanity. The emergent situation urgently called for investments in vaccine development as a critica...
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Using quality risk management in the plantibody HB-01 manufacturing by transgenic tobacco Plants for vaccine production
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Using quality risk management in the plantibody HB-01 manufacturing by transgenic tobacco Plants for vaccine production
Mila C., Loreley et al · SEDICI UNLP · 2010
The production of biopharmaceuticals by transgenic plants is a promising choice to achieve the multi-kilogram amount of products needed to treat many human diseases. However, this scientific field is still lacking of app...
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Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine
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Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine
Lindsey R. Baden; Hana M. El Sahly; Brandon Essink; Karen Kotloff; Sharon Frey; Rick Novak; David Diemert; Stephen A. Spector · New England Journal of Medicine · 2020
BACKGROUND: Vaccines are needed to prevent coronavirus disease 2019 (Covid-19) and to protect persons who are at high risk for complications. The mRNA-1273 vaccine is a lipid nanoparticle-encapsulated mRNA-based vaccine ...
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New vaccine for influenza virus H1N1 : Pharmacosurveillance of adverse reactions in health staff at Hospital San Luis, Argentina
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New vaccine for influenza virus H1N1 : Pharmacosurveillance of adverse reactions in health staff at Hospital San Luis, Argentina
Sarmiento, María G. et al · SEDICI UNLP · 2011
In March 2010, the Immunization Program of San Luis Province began a vaccination campaign against influenza A H1N1 with monovalent and trivalent vaccines. Being this the first year that this vaccine is used, and followin...
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