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BackgroundThe study assessed the epigenetic regulation and the role of microRNA (miR) expression in locally advanced triple negative breast cancers (TNBC) and comparison with the clinico-pathological variables and surviv...

There is an increasing heavy disease burden of major depressive disorder (MDD) globally. Both high diagnostic heterogeneity and complicated pathological mechanisms of MDD pose significant challenges. There is much eviden...

Post-traumatic stress disorder (PTSD) is a severe neuropsychiatric disorder characterised by re-experiencing, avoidance and hyperarousal. Memory abnormalities manifested as intrusive thoughts and prolonged distressful em...

IntroductionMetabolism-associated fatty liver disease (MAFLD) has emerged as a severe worldwide public health burden with insufficient available clinical therapeutic strategies, which underscores the urgent demand for sa...

Abstract Background This study aims to evaluate the effectiveness and real-world applicability of total neoadjuvant therapy (TNT) in patients with locally advanced rectal cancer (LARC), focusing on pathological complete ...

El objetivo de este trabajo consiste en estudiar si la percepción que tienen los niños de su relación con sus padres y de la empatía de sus padres se relacionan con la conducta prosocial en la infancia. Se trabajó c...

Among the Middle Pleistocene African fossils that are central to discussions about the evolution of Homo sapiens is the partial cranium from Florisbad, South Africa. The fossil, dated to MIS 8 (300–243 ka BP), combines...

Saliva as a microfluidic system offers numerous advantages for both general and oral health diagnostic and therapeutic procedures since its assembly is quick, stress-free, inexpensive and non-invasive. Moreover, saliva i...

BackgroundNFKB1 encodes the p105/p50 nuclear factor-kappa-B (NF-κB1) transcription factor. Heterozygous mutations in NFKB1 are associated with NFKB1-related disease, including granulomatous-lymphocytic interstitial lung...

The aim of this study was to evaluate the variations of Acute Phase Proteins (APPs) and other blood constituents during the onset of the sub-acute ruminal acidosis (SARA) pathological status. A total of 108 cows from 12 ...

Abstract Background Triple-negative breast cancer (TNBC) is an aggressive subtype with limited therapeutic targets. Hypoxia, autophagy, apoptosis, and translational stress are key biological processes involved in tumor p...

ObjectiveTo evaluate the diagnostic value of 3.0 T endovaginal coil magnetic resonance imaging technique for early cervical cancer.MethodsForty patients with early cervical cancer admitted to the gynecology department ...

Background Lupus nephritis (LN) is a leading cause of mortality in patients with systemic lupus erythematosus (SLE), and the accurate classification of renal pathological subtypes is crucial for reducing mortality rates ...

Polyomavirüs, type BK is an important viral infection of the allograft kidney. Although BKV infected urethelial cell can be encountered frequently urinal infection, it is unlikely to found renal infection in renal allog...

Background/Aim: Cysts which appear in the orofacial region are represented as common pathological changes which underlying mechanism of development is still not fully clear. In recent years, a dominant role in the pathog...

ObjectiveThe present investigation is designed to assess the synergistic impact of endoscopic ultrasonography (EUS)paired with endoscopic therapy in addressing upper gastrointestinal (GI) lesions that protrude.MethodsOur...

This paper examines the meanings constructed around adolescence, withtheir implications for the practices of physicians and nurses working within theFamily Health Strategy (FHS) in amunicipality in the interior of the St...

ObjectiveObserve the effect of （Mixed aqueous extract of Anemarrhenae Rhizoma， Gastrodiae Rhizoma， Alpiniae Oxyphyllae Fructus and Poria Cocos， CGTI） on the cognitive ability of mice with memory impairment indu...

Abstract Objective To investigate the influence of postoperative pathological factors (including variables not categorized as moderate - to - high - risk factors according to the Sedlis criteria) on the prognosis and lym...

Connective tissue diseases are a group of diseases with a complex etiology characterized by abnormal activity of the immune system. In the last decade, the role of the gut microbiota as a potential modulator of diseases ...

Se realizó un estudio microbiológico de 100 pulmones obtenidos al azar provenientes de capones y hembras sin servicio faenados en diferentes mataderos. Estos fueron clasificados macroscópicamente en pulmones con lesio...

La ascitis quilosa es un hallazgo poco frecuente en la clínica de pequeños animales. En su mayoría se originan a partir de alteraciones intra-abdominales tales como ruptura de vasos linfáticos, neoplasias que obstruy...

La abiotrofia neuronal es una degeneración prematura de neuronas debida a una anomalía hereditaria del metabolismo celular, que comienza en los primeros meses de vida. La aparición de los signos ocurre semanas o inclu...

El Complejo Leucósico Aviar comprende por lo menos dos enfermedades con características etiológicas y patológicas propias. En los últimos años se han realizado importantes avances en la investigación de las enferm...