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Background and purposeThe aging brain is particularly sensitive to alterations in selenium status. Selenium deficiency has been associated with impaired neural function, cognitive decline, and increased vulnerability to ...

BackgroundParkinson’s disease (PD) is a neurodegenerative disorder characterized by the progressive loss of dopaminergic neurons, leading to a spectrum of motor and non-motor symptoms. In addition to the motor deficits...

IntroductionParkinson’s disease (PD) is the second most common neurodegenerative disorder. The risk of frailty is significantly higher in patients with PD than in age-matched individuals without PD. This study aimed to...

Abstract Objective and study design A retrospective study analyzes the validity of Omar’s sign for the clinical diagnosis of unilateral lumbar foraminal stenosis. Methods This study analyses 800 patients having unilate...

Abstract Background Scurvy has re-emerged in association with neurodevelopmental and eating disorders, particularly selective eating. This study aimed to investigate the clinical characteristics of pediatric scurvy cases...

Abstract Background Takotsubo syndrome (broken-heart syndrome) is considered a cardiac disorder typically associated with exposure to severe psychological or physical stress, and it clinically resembles acute coronary sy...

Introduction: One of the most serious mental health issues in Indonesia is stigma. Schizophrenia is a mental illness that carries a lot of stigma. Stigma makes people with schizophrenia distinct and undervalued, so it ca...

Aim: Stroke represents a leading cause of mortality and disability globally, yet comprehensive epidemiological analyses for Saudi Arabia remain limited. This study aimed to analyze temporal trends in stroke incidence, mo...

Introduction: Burnout, also known as professional fatigue syndrome, results from prolonged stress in the workplace. Healthcare workers are particularly vulnerable to burnout and depression due to the nature of their work...

Introduction: Gastroesophageal Reflux Disease (GERD) is a disorder of reflux of gastric contents into the esophagus, which can cause symptoms and complications. The global prevalence of GERD is 25% in adults, 20% in West...

Introductions: Adolescence is a critical phase in the transition to adulthood. It is marked by several challenges for teenagers, including an increase in delinquent behavior, substance abuse, and premature engagement in ...

Introduction: Among stroke survivors, psychiatric complications such as post-stroke depression (PSD) are common, affecting about a third of stroke survivors. Antidepressant therapy is regarded as the preferred approach f...

Introduction: Social Anxiety Disorder (SAD) is one of the most common forms of anxiety. SAD typically begins in late adolescence and is the cause of low self-esteem. This study aimed to investigate the unidentified cause...

Introductions: Career decision-making in female Balinese high school students is influenced by parental attachment, particularly in a patriarchal cultural context. This study examines the role of attachment to fathers an...

Abstract Despite growing recognition of the role of employee well-being in organisational outcomes, limited empirical research has examined how employee mental health covaries with corporate sustainability through market...

BackgroundAccurate categorisation of the upward rotation of the foetal cerebellar vermis continues to pose diagnostic challenges in prenatal medicine. Recently, a new parameter of the posterior fossa (PF), known as the v...

Abstract Background Irritable bowel syndrome (IBS) is a prevalent disorder of gut-brain interaction in which psychosocial factors can exacerbate symptoms. Although cognitive behavioral therapy (CBT) has proven effective ...

In addition to maintaining the GenBank(R) nucleic acid sequence database, the National Center for Biotechnology Information (NCBI) provides data analysis and retrieval resources for the data in GenBank and other biologic...

BACKGROUND: Functional annotation of differentially expressed genes is a necessary and critical step in the analysis of microarray data. The distributed nature of biological knowledge frequently requires researchers to n...

UNLABELLED: The two main functions of bioinformatics are the organization and analysis of biological data using computational resources. Geneious Basic has been designed to be an easy-to-use and flexible desktop software...

A critical component in the interpretation of systems-level studies is the inference of enriched biological pathways and protein complexes contained within OMICs datasets. Successful analysis requires the integration of ...

SUMMARY: It is expected that emerging digital gene expression (DGE) technologies will overtake microarray technologies in the near future for many functional genomics applications. One of the fundamental data analysis ta...

BACKGROUND: Gene-expression analysis is increasingly important in biological research, with real-time reverse transcription PCR (RT-PCR) becoming the method of choice for high-throughput and accurate expression profiling...

Non-biological experimental variation or "batch effects" are commonly observed across multiple batches of microarray experiments, often rendering the task of combining data from these batches difficult. The ability to co...