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Magnetic Resonance Imaging is one of the most important medical imaging techniques for the investigating diseases of the human brain. A novel method for automatic segmentation Magnetic resonance brain image framework is ...

"Brain Computer Interface (BCI) or Brain Machine Interfaces (BMI), has proved the feasibility of a distinct non-biological communication channel to transmit information from the Central Nervous System (CNS) to a computer...

Thirty years of brain imaging research has converged to define the brain's default network-a novel and only recently appreciated brain system that participates in internal modes of cognition. Here we synthesize past obse...

Materias / palabras clave: neurobiology, brain function, brain dysfunction, brain disorders; Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry: Neurology. Diseases of the nervous system

Materias / palabras clave: deep brain stimulation, brain stimulation, neuromodulation, neurotechnology, brain; Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry; Science: Physiology: Neurophysiology and neuropsycho...

ObjectiveChronic pain, a major global public health burden, is primarily driven by altered central pain processing, which conventional treatments rarely target directly. This systematic review and meta-analysis synthesiz...

Abstract Postoperative neurocognitive disorder (PND) is a frequent complication in elderly surgical patients and is closely associated with blood-brain barrier (BBB) disruption and cerebral metabolic imbalance. The prese...

The electroencephalogram (EEG) is an electrophysiological monitoring method that allows us to glimpse the electrical activity of the brain. Neural oscillations patterns are perhaps the best salient feature of EEG as they...

Objective: To investigate the time-dependent progression of cranial radiation-induced testicular injury in mice, focusing on apoptotic pathways and brain-testis axis involvement. Methods: Male mice were randomly divided ...

Abstract The development of trustworthy AI models is crucial, particularly for critical medical applications such as brain tumor detection using MRI images. However, medical images are being increasingly targeted by adve...

Parkinson’s disease (PD) is characterized by profound metabolic disturbances in the brain, yet how these alterations vary across brain regions and respond to neuroprotective intervention remains poorly understood. Here...

In the growing diversity of human induced pluripotent stem cell (iPSC)-derived models of brain development, we present here a novel method that exhibits 3D cortical layer formation in a reproducible topography of minimal...

Abstract Purpose Prader-Willi Syndrome (PWS) is a rare genetic disorder with a heterogeneous phenotype, caused by loss of expression of genes on the paternally inherited chromosome 15q11.2-15q13.3, primarily due to pater...

Perinatal asphyxia (PA) is a primary cause of neonatal morbidity, with persistent neurological sequelae, associated with mitochondrial dysfunction and redox imbalance. The lack of experimental approaches for region-speci...

There is a growing interest in the potential of mesenchymal stem cells (MSCs) for implementing regenerative medicine in the brain as they have shown neurogenic and immunomodulatory activities. We assessed the effect of i...

Lucie Bartova,1 Mara Lisa Beuster,2 Bruno Bonetti,3 Giuseppe Maina,4,5 Pedro Morgado,6 Johan Nyberg7 1Department of Psychiatry and Psychotherapy, Clinical Division of General Psychiatry, and Comprehensive Center for Clin...

Abstract The dissemination route of brain metastases dictates their spatiotemporal distribution, but whether it alters the ultrastructural state of the blood-tumor barrier remains unresolved. Here, we compared a modified...

Recent historical works dealing with the changing role of emotions in social and private life over centuries present a challenge to any philosophical or scientific theory aiming to grasp the essence of emotions. The pape...

BackgroundCurrent prognostic models for cerebral venous sinus thrombosis (CVST) inadequately predict long-term cognitive and functional outcomes, focusing primarily on survival. We aimed to develop and validate a simple,...

The misuse of opioids has reached epidemic proportions over the last decade, with over 2.1 million people in the United States suffering from substance use disorders related to prescription opioid pain relievers. This in...

Abstract Brain pericytes are mediators of neuroinflammation, as evidenced in vitro, in animal models and humans. We and others have identified the platelet-derived growth factor (PDGF)-BB -PDGF receptor beta (PDGFRB) pat...

ABSTRACT Background Current diagnosis of brain disease in dogs is dependent on imaging and cerebrospinal fluid (CSF) analysis, including total nucleated cell counts and albumin concentrations. Hypothesis/Objectives To de...

Abstract Accumulation of amyloid beta 1–42 (Aβ42) peptide in the extracellular space in the brain is a major observation in Alzheimer’s Disease (AD)-related pathology. Astrocytes are known to play pivotal role in cl...

"This paper presents a supervised classification method to accurately detect epileptic brain activity in real-time from electroencephalography (EEG) data. The proposed method has three main strengths: it has low computat...