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120 resultados encontrados.

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The mechanism of different microglial receptors mediating central inflammation in chronic migraine: a meta-analysis
Artículo
Acceso abierto Artículo DOAJ
Xinyu Lin et al · BMC · 2026 · ISSN 1129-2377
Abstract Background Microglial activation is increasingly recognized as a critical contributor to both the initiation and chronification of migraine. Recent advances have highlighted the importance of receptor-mediated s...
LCC LCC:MedicineIdioma eng
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Open Access
A dioxin-like compound induces hyperplasia and branching morphogenesis in mouse mammary gland, through alterations in TGF-β1 and aryl hydrocarbon receptor signaling
Artículo
Acceso abierto Artículo CONICET Digital
Miret, Noelia Victoria et al · Academic Press Inc Elsevier Science · 2017 · ISSN 0041-008X
Hexachlorobenzene (HCB) is a widespread environmental pollutant and a dioxin-like compound that binds weakly to the aryl hydrocarbon receptor (AhR). Because AhR and transforming growth factor β1 (TGF-β1) converge to re...
Idioma eng
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Open Access
Anatomical histological and histochemical structure of the retina in Mabuya aurata lizard
Artículo
Acceso abierto Artículo DOAJ
Sanabel Al-Thanon · University of Mosul, College of Education for Pure Science · 2012 · ISSN 1812-125X
ABSTRACT The present study carried out to explore the anatomical morphology and histological structure, as well as some histochiemical aspects of the retina in Mabuya aurata lizard which is a carnivorous animal. On the o...
LCC TENDOkVkdWNhdGlvbg~~; LCC:Science (General)Idioma eng
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Open Access
Automated reporter quantification in vivo: high-throughput screening method for reporter-based assays in zebrafish.
Artículo
Material complementario disponible Artículo DOAJ
Steven L Walker et al · Public Library of Science (PLoS) · 2012 · ISSN 1932-6203
Reporter-based assays underlie many high-throughput screening (HTS) platforms, but most are limited to in vitro applications. Here, we report a simple whole-organism HTS method for quantifying changes in reporter intensi...
LCC LCC:Medicine; TENDOlNjaWVuY2U~Idioma eng
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Material complementario
Clinico-hematological characteristics of hematological malignancy in pediatric age group in Madhya Pradesh: A tertiary care experience
Artículo
Material complementario disponible Artículo DOAJ
Pragya Chaurasia et al · Manipal College of Medical Sciences, Pokhara · 2026 · ISSN 2467-9100
Background: Hematological malignancies, encompassing leukemia, lymphoma, and myeloma, constitute a significant cause of morbidity and mortality. Early diagnosis plays a pivotal role in improving prognosis and facilitatin...
LCC LCC:MedicineIdioma eng
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Material complementario
Connexin 32 constrains a mesenchymal-like switch in differentiated urothelium and luminal cancers
Artículo
Acceso abierto Artículo DOAJ
Jennifer Hinley et al · Life Science Alliance LLC · 2026 · ISSN 2575-1077
We reveal a coordinating role for Cx32-mediated cell–cell communication in maintaining mitotic-quiescence and limiting migration-associated TGFβ signalling, extracellular matrix remodelling and mesenchymal-like change...
LCC LCC:Medicine; LCC:Biology (General)Idioma eng
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Open Access
Cytotoxic evaluation of essential oil from Zanthoxylum rhoifolium Lam. leaves Avaliação citotóxica do óleo volátil extraído das folhas do Zanthoxylum rhoifolium Lam.
Artículo
Acceso abierto Artículo DOAJ
Saulo Luis da Silva et al · Instituto Nacional de Pesquisas da Amazônia · 2007 · ISSN 0044-5967
Zanthoxylum rhoifolium Lam is a plant popularly used as antimicrobial, for malaria and inflammatory treatment. The essential oil of Z. rhoifolium was extracted and its cytotoxic effects against HeLa (human cervical carci...
LCC LCC:Science (General)Idioma eng
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Open Access
Donkey serum albumin improves cyclophosphamide-induced anemia in mice
Artículo
Material complementario disponible Artículo DOAJ
Qin Nan et al · De Gruyter · 2026 · ISSN 2391-5412
Cyclophosphamide (CP) is commonly used in cancer chemotherapy and the treatment of autoimmune diseases. In clinical applications, it exhibits the side effect of progressive anemia. Donkey serum albumin (DSA) is the most ...
LCC LCC:Biology (General)Idioma eng
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Material complementario
Efficacies of Potential Probiotic Candidates Isolated from Traditional Fermented Korean Foods in Stimulating Immunoglobulin A Secretion
Artículo
Acceso abierto Artículo DOAJ
Chang-Yong Choi et al · Springer Nature · 2023 · ISSN 2636-0772
Abstract The aim of this study was to evaluate efficacies of selected lactic acid bacteria (LAB) in inducing immunoglobulin A (IgA) secretion. Twenty-five different LAB isolated from traditional fermented Korean foods we...
LCC TENDOkZvb2QgcHJvY2Vzc2luZyBhbmQgbWFudWZhY3R1cmU~; LCC:Animal cultureIdioma eng
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Open Access
Evaluation of Non-Thermal Decontamination Processes to Have the Equivalence of Thermal Process in Raw Ground Chicken
Artículo
Acceso abierto Artículo DOAJ
Eunyoung Park et al · Springer Nature · 2022 · ISSN 2636-0772
Abstract The present study was aimed at examining the antibacterial effects of non-thermal decontamination processes, which are equivalent to thermal treatment, to ensure microbiological safety of raw ground chicken. Esc...
LCC TENDOkZvb2QgcHJvY2Vzc2luZyBhbmQgbWFudWZhY3R1cmU~; LCC:Animal cultureIdioma eng
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Open Access
F-actin organization excludes E-cadherin from the division furrow to ensure cytokinesis fidelity
Artículo
Material complementario disponible Artículo DOAJ
Debodyuti Mondal et al · Life Science Alliance LLC · 2026 · ISSN 2575-1077
Localization of the cell adhesion receptor E-cadherin within the furrow is associated with reduced cytokinetic fidelity. Cortical organization of formin-polymerized linear actin filaments at the division zone physically ...
LCC LCC:Medicine; LCC:Biology (General)Idioma eng
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GAS6 signaling tempers Th17 development in patients with multiple sclerosis and helminth infection
Artículo
Acceso abierto Artículo CONICET Digital
Ortiz Wilczyñski, Juan Manuel et al · Public Library of Science · 2020 · ISSN 1553-7366
Multiple sclerosis (MS) is a highly disabling neurodegenerative autoimmune condition in which an unbalanced immune response plays a critical role. Although the mechanisms remain poorly defined, helminth infections are kn...
Idioma eng
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Open Access
Glucocorticoids suppress early lung inflammation and impair control of SARS-CoV-2 in non-human primates.
Artículo
Acceso abierto Artículo DOAJ
Christine E Nelson et al · Public Library of Science (PLoS) · 2026 · ISSN 1932-6203
In severe cases of COVID-19, glucocorticoid treatment improves clinical outcomes. However, in non-hospitalized patients, glucocorticoids have limited benefit and may impair viral clearance. Here, we used the rhesus macaq...
LCC LCC:Medicine; TENDOlNjaWVuY2U~Idioma eng
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Open Access
Hovenia Monofloral Honey can Attenuate Enterococcus faecalis Mediated Biofilm Formation and Inflammation
Artículo
Acceso abierto Artículo DOAJ
Ri You et al · Springer Nature · 2022 · ISSN 2636-0772
Abstract We evaluated the anti-biofilm formation and anti-inflammatory activity of Hovenia monofloral honey (HMH) against Enterococcus faecalis. Co-culture of HMH with E. faecalis attenuated the biofilm formation of E. f...
LCC TENDOkZvb2QgcHJvY2Vzc2luZyBhbmQgbWFudWZhY3R1cmU~; LCC:Animal cultureIdioma eng
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Open Access
Industrial Research and Development on the Production Process and Quality of Cultured Meat Hold Significant Value: A Review
Artículo
Acceso abierto Artículo DOAJ
Kyu-Min Kang et al · Springer Nature · 2024 · ISSN 2636-0772
Abstract Cultured meat has been gaining popularity as a solution to the increasing problem of food insecurity. Although research on cultured meat started later compared to other alternative meats, the industry is growing...
LCC TENDOkZvb2QgcHJvY2Vzc2luZyBhbmQgbWFudWZhY3R1cmU~; LCC:Animal cultureIdioma eng
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Open Access
Mathematical Models to Describe the Kinetic Behavior of Staphylococcus aureus in Jerky
Artículo
Acceso abierto Artículo DOAJ
Jimyeong Ha et al · Springer Nature · 2019 · ISSN 2636-0772
Abstract The objective of this study was to develop mathematical models for describing the kinetic behavior of Staphylococcus aureus (S. aureus) in seasoned beef jerky. Seasoned beef jerky was cut into 10-g pieces. Next,...
LCC TENDOkZvb2QgcHJvY2Vzc2luZyBhbmQgbWFudWZhY3R1cmU~; LCC:Animal cultureIdioma eng
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Open Access
Oral Administration of Lactilactobacillus curvatus LB-P9 Promotes Hair Regeneration in Mice
Artículo
Acceso abierto Artículo DOAJ
Mikyung Song et al · Springer Nature · 2024 · ISSN 2636-0772
Abstract This study was designed to examine the effect of Lactilactobacillus curvatus LB-P9 on hair regeneration. The treatment of LB-P9 conditioned medium increased the proliferation of both hair follicle dermal papilla...
LCC TENDOkZvb2QgcHJvY2Vzc2luZyBhbmQgbWFudWZhY3R1cmU~; LCC:Animal cultureIdioma eng
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Open Access
Pathologies at the gateway: exploring the link between nucleoporins and inherited diseases
Artículo
Acceso abierto Artículo DOAJ
Daniela A. Braun et al · Springer · 2026 · ISSN 1420-9071
Abstract Nuclear pore complexes serve as essential gatekeepers of the nuclear envelope, playing crucial roles in regulating transport across the nuclear envelope and maintaining compartmentalization between the nucleus a...
LCC LCC:Biology (General); TENDOk1pY3JvYmlvbG9neQ~~Idioma eng
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Open Access
Polystyrene microplastics impair mouse oocyte maturation by interfering with fatty acid oxidation
Artículo
Acceso abierto Artículo DOAJ
Zhiqiang Liu et al · SpringerOpen · 2026 · ISSN 2190-4715
Abstract Microplastics (MPs) represent a significant environmental pollutant and have raised considerable concern due to their tendency to accumulate in animals, plants, and humans, thereby posing potential health risks....
LCC TENDOkVudmlyb25tZW50YWwgc2NpZW5jZXM~; LCC:Environmental lawIdioma eng
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Open Access
RETRACTED: A new compound of thiophenylated pyridazinone IMB5043 showing potent antitumor efficacy through ATM-Chk2 pathway.
Artículo
Material complementario disponible Artículo DOAJ
Jianhua Gong et al · Public Library of Science (PLoS) · 2018 · ISSN 1932-6203
Through cell-based screening models, we have identified a new compound IMB5043, a thiophenylated pyridazinone, which exerted cytotoxicity against cancer cells. In the present study, we evaluated its antitumor efficacy an...
LCC LCC:Medicine; TENDOlNjaWVuY2U~Idioma eng
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Unveiling tetrahydroquinolines as promising BVDV entry inhibitors: Targeting the envelope protein
Artículo
Acceso abierto Artículo CONICET Digital
Leal, Emilse Soledad et al · Academic Press Inc Elsevier Science · 2024 · ISSN 0042-6822
Bovine viral diarrhea virus (BVDV) is known to cause financial losses and decreased productivity in the cattle industry worldwide. Currently, there are no available antiviral treatments for effectively controlling BVDV i...
Idioma eng
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Open Access
Visualization and quantification of cytotoxicity mediated by antibodies using imaging flow cytometry
Artículo
Acceso abierto Artículo CONICET Digital
Helguera, Gustavo Fernando et al · Elsevier Science · 2011 · ISSN 0022-1759
Conventional approaches for the detection of antibody dependent cell-mediated cytotoxicity (ADCC) activity rely on quantification of the release of traceable compounds from target cells or flow cytometry analysis of popu...
Idioma eng
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Open Access
investigate the development of the olfactory organ and its histological structure of the amphibians Salamander Neurergus crocatus crocatus cope
Artículo
Acceso abierto Artículo DOAJ
Hane Hammode et al · University of Mosul, College of Education for Pure Science · 2009 · ISSN 1812-125X
ABSTRACT The present study is carried out to investigate the development of the olfactory organ and it`s histological structure in the embryos, Larvae and adults of urodele amphibians Salamander Neurergus crocatus crocat...
LCC TENDOkVkdWNhdGlvbg~~; LCC:Science (General)Idioma eng
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Open Access
Cellular solids structure and properties
Libro electrónico
Página del recurso disponible Libro electrónico OpenAlex
Lorna J. Gibson; Michael F. Ashby · OpenAlex · 1997
In this new edition of their classic work on Cellular Solids, the authors have brought the book completely up to date, including new work on processing of metallic and ceramic foams and on the mechanical, electrical and ...
Idioma en
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