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Introduction: As the prevalence of metabolic dysfunction–associated steatotic liver disease (MASLD), formerly NAFLD, continues to rise, increasing numbers of patients with hepatic dysfunction are undergoing elective or...

ABSTRACT Background and Aims Diabetic peripheral neuropathy (DPN) is the most prevalent complication of diabetes, leading to functional impairment and a decline in patients' quality of life. The objectives of the present...

Background Obsessive-compulsive disorder (OCD) is classified by the World Health Organization as 1 of the 10 most disabling conditions. However, nationally representative epidemiological data on OCD are not yet available...

Abstract Background The occurrence of potential drug‒drug interactions (pDDIs) is a serious global issue that affects all age groups, with the elderly population being the most vulnerable. This is due to their relative...

Objectives: Psychiatric disorders are frequently found in both patients with PNES and DRE, making the differential diagnosis even more complex. The aim of this study was to analyze and compare psychiatric aspects and the...

Vitiligo is a chronic depigmenting disorder that imposes a substantial psychological, social, and economic burden, extending beyond its physical manifestations. This narrative review synthesizes and critically evaluates ...

Key Points. C3 glomerulopathy and primary immune complex-mediated membranoproliferative GN lead to a significant clinical, economic, and health care burden among affected patients and their families. C3 glomerulopathy an...

This Campbell systematic review examines the effects of recovery schools on student behavioral and academic outcomes, compared to the effects of non‐recovery schools. The review summarizes evidence from one quasi‐exp...

Abstract Since the first report in 1972, several studies have documented an association between Parkinson’s disease (PD) and melanoma. Up to 20-fold increased risk of melanoma was reported in PD patients, while a perso...

Abstract Background Therapeutic Communities (TCs) are long-term residential treatment settings for individuals with substance use disorders, who often present with neuropsychological impairments. These impairments may in...

Aim: To investigate whether RhoA/ROCK pathway genes (RHOA, ROCK1, ROCK2) are differentially expressed in tunica albuginea of patients with congenital penile curvature (CPC) relative to Peyronie's disease (PD) and erectil...

Background: Total joint arthroplasty (TJA) of the hip and knee are widely used surgical treatments for advanced cases of osteoarthritis. Despite its effectiveness, disparities in outcomes based on socioeconomic and geogr...

INTRODUCTION: Temporomandibular disorders (TMD) and eating disorders (ED) affect function and parafunction of the oral cavity and have high rates of medical and psychological comorbidity. However, little is known about t...

IntroductionImprovements in life expectancy imply that an increase of geriatric trauma patients occurs. These patients require special attention due to their multiple comorbidity issues. The aim of this study was to asse...

Abstract Juvenile idiopathic arthritis (JIA) is an umbrella term for a group of oligo- and poly-arthritic conditions that develop before 16 years of age. While the exact pathophysiology of JIA is still unknown, both gene...

Abstract Background Polypharmacy and pharmacokinetic alterations expose elderly patients to an increased risk of iatrogenic events, hospitalisation, and healthcare costs. Therapeutic optimisation is based on identifying ...

Background: Cardiac surgery is associated with a significant risk of postoperative pulmonary embolism (PE), a life-threatening complication. This study sought to evaluate the epidemiology, associated factors, and clinica...

Abstract Background Chronic neuropathic pain is frequently accompanied by anxiety and depression, yet the cortical circuit mechanisms underlying this comorbidity remain unclear. The medial orbitofrontal cortex (mOFC) is ...

Abstract Purpose This study examined the prevalence of post-traumatic stress disorder (PTSD) diagnoses among pregnant women who delivered in hospitals in the United States between 2016 and 2020, and explored associations...

ObjectiveThe prognostic implications of surgical outcomes in older adults with ovarian cancer remain unclarified. This study aimed to describe temporal trends in surgical management and examine the association between su...

Gencer Kurt,1 Rune Erichsen1,2 1Department of Clinical Epidemiology and Center for Population Medicine, Aarhus University Hospital and Aarhus University, Aarhus, Denmark; 2Department of Surgery, Randers Regional Hospital...

Managing multiple long-term conditions (MLTCs) is a growing priority for health and social care systems, as MLTCs often lead to frailty and reduced resilience to adverse health events. Behaviour change interventions for ...

BACKGROUND: There is no single generally accepted clinical definition of frailty. Previously developed tools to assess frailty that have been shown to be predictive of death or need for entry into an institutional facili...

OBJECTIVES: Implementation of the International Statistical Classification of Disease and Related Health Problems, 10th Revision (ICD-10) coding system presents challenges for using administrative data. Recognizing this,...