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A Chlamydia trachomatis CPAF-STING agonist conjugate vaccine administered intramuscularly and intradermally is immunogenic in the pig model

ISSN: 16643224 · Editor / fuente: Frontiers Media

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143

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A combined model of BCVA, TRAb, and NLR predicts response to intravenous methylprednisolone in dysthyroid optic neuropathy

ISSN: 2296858X · Editor / fuente: Frontiers Media S.A.

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132

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3D intelligent printing technology-assisted training improves core competencies of clinical medicine interns: bridging undergraduate further education and community health service needs

ISSN: 22962565 · Editor / fuente: Frontiers Media S.A.

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107

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Opportunistic routing in communications networks via learnable state-augmented policies
Artículo
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Opportunistic routing in communications networks via learnable state-augmented policies
Sourajit Das et al · Frontiers Media S.A · 2026 · ISSN 2673-530X
This paper addresses the challenge of packet-based information routing in large-scale communication networks. The problem is framed as a constrained statistical learning task, where each network node operates using only ...
LCC TENDOkNvbW11bmljYXRpb24uIE1hc3MgbWVkaWE~Idioma eng
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Optimisation of patient-reported outcome measurement for haematological cancer patients receiving novel immunotherapies: perspectives of multi-stakeholders
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Optimisation of patient-reported outcome measurement for haematological cancer patients receiving novel immunotherapies: perspectives of multi-stakeholders
Eilidh M Duncan et al · Frontiers Media S.A · 2026 · ISSN 2813-3935
ObjectivesThe primary objective of this project was to explore the challenges related to the implementation of patient-reported outcome measures (PROMs) in myeloma, lymphoma and leukaemia patients undergoing chimeric ant...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Oral losartan yields subtherapeutic airway exposure compared to nebulized delivery and fails to improve mucociliary clearance in cystic fibrosis
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Oral losartan yields subtherapeutic airway exposure compared to nebulized delivery and fails to improve mucociliary clearance in cystic fibrosis
Charles D. Bengtson et al · Frontiers Media S.A · 2026 · ISSN 1663-9812
BackgroundTransforming growth factor-β1 (TGF-β1) contributes to more severe pulmonary disease in people with cystic fibrosis (pwCF). Our preclinical in vitro and in vivo studies demonstrated that losartan could reverse...
LCC LCC:Therapeutics. PharmacologyIdioma eng
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Oxidized lipids as molecular biomarkers in carotid in-stent restenosis: mechanisms and clinical implications
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Oxidized lipids as molecular biomarkers in carotid in-stent restenosis: mechanisms and clinical implications
Qiao Chen et al · Frontiers Media S.A · 2026 · ISSN 1664-2295
Carotid artery stenting (CAS) has emerged as an effective alternative to carotid endarterectomy for treating carotid artery stenosis, particularly in high-risk surgical patients. However, in-stent restenosis (ISR) remain...
LCC LCC:Neurology. Diseases of the nervous systemIdioma eng
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Post-stroke insomnia: multidimensional mechanisms, clinical heterogeneity, and toward mechanism-informed, objectively quantified management
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Post-stroke insomnia: multidimensional mechanisms, clinical heterogeneity, and toward mechanism-informed, objectively quantified management
Jinlian Liao et al · Frontiers Media S.A · 2026 · ISSN 1664-2295
Stroke survivors frequently experience sleep disturbance, among which post-stroke insomnia (PSI) is common yet often underrecognized across the post-stroke course. Although its clinical expression may vary over time, PSI...
LCC LCC:Neurology. Diseases of the nervous systemIdioma eng
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Precuneus hyperexcitability mediates inflammatory-driven pain hypersensitivity following sleep disruption: a multimodal neuroimaging study
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Precuneus hyperexcitability mediates inflammatory-driven pain hypersensitivity following sleep disruption: a multimodal neuroimaging study
Chao Li et al · Frontiers Media S.A · 2026 · ISSN 1664-3224
BackgroundSleep disruption(SD) has been shown to amplify inflammatory signaling and promote pain hypersensitivity, but how inflammation interacts with brain functional alterations to drive pain sensitization remains uncl...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Profiling perceived challenges in Mathematics in the Modern World to inform Math-RetoKiSS: a data-informed blended learning support system for 21st-century mathematics learning in a Philippine university
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Profiling perceived challenges in Mathematics in the Modern World to inform Math-RetoKiSS: a data-informed blended learning support system for 21st-century mathematics learning in a Philippine university
Imelda M. Flores et al · Frontiers Media S.A · 2026 · ISSN 2504-284X
Mathematics in the Modern World (MMW) is a core general education course that develops quantitative reasoning and applied problem solving, yet many first-year students struggle with its concepts and applications. Such ch...
LCC TENDOkVkdWNhdGlvbiAoR2VuZXJhbCk~Idioma eng
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Prognostic model for predicting recurrence-free survival in HBV-related hepatocellular carcinoma patients after combined treatment: a multicenter study
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Prognostic model for predicting recurrence-free survival in HBV-related hepatocellular carcinoma patients after combined treatment: a multicenter study
Bojun Liu et al · Frontiers Media S.A · 2026 · ISSN 2234-943X
IntroductionHepatocellular carcinoma (HCC) is a lethal malignancy, with hepatitis B virus (HBV) infection as its leading cause in China. Transarterial chemoembolization (TACE) combined with radiofrequency ablation (RFA) ...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Psychosocial burden and coping strategies among lymphoma patients: a nurse-led hematology care approach
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Psychosocial burden and coping strategies among lymphoma patients: a nurse-led hematology care approach
Yan Wang et al · Frontiers Media S.A · 2026 · ISSN 1664-1078
BackgroundPatients with lymphoma frequently experience significant psychosocial burden, including anxiety, depression, and impaired quality of life, which may persist throughout the disease trajectory. Coping strategies ...
LCC TENDOlBzeWNob2xvZ3k~Idioma eng
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Real-world evidence of lower-dose intensity of immune checkpoint inhibitors in MSI-H/dMMR gastrointestinal cancers from a resource-constrained setting
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Real-world evidence of lower-dose intensity of immune checkpoint inhibitors in MSI-H/dMMR gastrointestinal cancers from a resource-constrained setting
Mohamad Mourad et al · Frontiers Media S.A · 2026 · ISSN 2234-943X
BackgroundImmune checkpoint inhibitors (ICIs) have markedly improved outcomes in metastatic microsatellite instability-high (MSI-H) or deficient mismatch repair (dMMR) gastrointestinal (GI) malignancies. However, in frag...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Research advances in connective tissue disease-associated pulmonary arterial hypertension with an emphasis on the Chinese population
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Research advances in connective tissue disease-associated pulmonary arterial hypertension with an emphasis on the Chinese population
Baocheng Liu et al · Frontiers Media S.A · 2026 · ISSN 2296-858X
Connective tissue disease-associated pulmonary arterial hypertension (CTD-PAH) is a severe pulmonary complication of connective tissue diseases (CTDs) that occurs in approximately 30% of adult patients with pulmonary art...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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Retrospective analysis of clinical efficacy and safety of fluorometholone combined with azelastine eye drops for seasonal allergic conjunctivitis
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Retrospective analysis of clinical efficacy and safety of fluorometholone combined with azelastine eye drops for seasonal allergic conjunctivitis
Xiangjun Dai et al · Frontiers Media S.A · 2026 · ISSN 2296-858X
BackgroundSeasonal allergic conjunctivitis (SAC) is a common ocular allergic disease, predominantly affecting children and young adults, with no significant gender predominance.AimThis study aimed to retrospectively eval...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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Risk factors and predictive model for cervical lymph node metastasis in papillary thyroid carcinoma of the isthmus: a retrospective analysis of clinical and ultrasonographic features
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Risk factors and predictive model for cervical lymph node metastasis in papillary thyroid carcinoma of the isthmus: a retrospective analysis of clinical and ultrasonographic features
Jia-Sheng Ding et al · Frontiers Media S.A · 2026 · ISSN 2234-943X
ObjectiveThis study aimed to investigate the clinical and ultrasonographic characteristics of papillary thyroid carcinoma (PTC) located in the thyroid isthmus and to identify independent risk factors predicting cervical ...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Serum bile acid metabolic profiles in polycystic ovary syndrome: insights from targeted metabolomics and correlation with embryonic parameters
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Serum bile acid metabolic profiles in polycystic ovary syndrome: insights from targeted metabolomics and correlation with embryonic parameters
Jialai Wang et al · Frontiers Media S.A · 2026 · ISSN 2296-889X
ObjectivePolycystic ovary syndrome (PCOS) is a complex endocrine disorder. In this study, we characterize serum bile acids (BAs) metabolic profiles in PCOS patients using targeted metabolomics and investigated their corr...
LCC LCC:Biology (General)Idioma eng
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Shared variance in creative self-beliefs: examining self-compassion and personality traits in creative adolescents and adults
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Shared variance in creative self-beliefs: examining self-compassion and personality traits in creative adolescents and adults
Michael P. Diana et al · Frontiers Media S.A · 2026 · ISSN 1664-1078
IntroductionCreative self-beliefs are shaped by stable personality traits and psychological resources. While the links between the creative personality and creative self-beliefs are established, the role of self-compassi...
LCC TENDOlBzeWNob2xvZ3k~Idioma eng
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Targeting the miR-32533/CREB5 axis: a promising immunomodulatory and therapeutic strategy for Alzheimer’s disease
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Targeting the miR-32533/CREB5 axis: a promising immunomodulatory and therapeutic strategy for Alzheimer’s disease
Lizhen Li et al · Frontiers Media S.A · 2026 · ISSN 1664-3224
Materias / palabras clave: Alzheimer’s disease; amyloid-beta; miR-32533/CREB5 pathway; neuroinflammation; oxidative stress; therapeutic strategy
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Taurine and glutamine supplementation in aging: systemic mechanisms, exercise interactions, and modulation of muscular and neurobiological pathways
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Taurine and glutamine supplementation in aging: systemic mechanisms, exercise interactions, and modulation of muscular and neurobiological pathways
Zhigang Chen et al · Frontiers Media S.A · 2026 · ISSN 1664-042X
The senescence of the neuro-skeletal muscle system is typified by a gradual deterioration in muscle mass, strength, neuromuscular efficacy, and cognitive capabilities, which is further exacerbated by metabolic dysregulat...
LCC TENDOlBoeXNpb2xvZ3k~Idioma eng
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Technological integration and professional competency development: a structural equation analysis of generative AI, learning engagement, and media literacy in journalism education
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Technological integration and professional competency development: a structural equation analysis of generative AI, learning engagement, and media literacy in journalism education
Lifang Chen et al · Frontiers Media S.A · 2026 · ISSN 2504-284X
This study investigates how generative artificial intelligence (AI) integration affects professional skill development in journalism education through learning engagement and media literacy. Conducted between September 2...
LCC TENDOkVkdWNhdGlvbiAoR2VuZXJhbCk~Idioma eng
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The foliar potassium silicate enhances wheat terminal-drought tolerance and yield via physiological, biochemical and genetic regulation
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The foliar potassium silicate enhances wheat terminal-drought tolerance and yield via physiological, biochemical and genetic regulation
Yahya Alzahrani et al · Frontiers Media S.A · 2026 · ISSN 1664-462X
Drought stress limits wheat productivity at terminal stage by disrupting physiological activities, impairing cellular homeostasis, and decreasing grain yield. Present study elucidated the role of potassium silicate (K2Si...
LCC TENDOlBsYW50IGN1bHR1cmU~Idioma eng
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The impact of green finance on corporate environmental performance: the moderating role of economic policy uncertainty
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The impact of green finance on corporate environmental performance: the moderating role of economic policy uncertainty
Vidura Perera et al · Frontiers Media S.A · 2026 · ISSN 2813-2823
IntroductionGreen finance has emerged as a critical mechanism for enhancing corporate environmental performance (CEP) and achieving global sustainability goals. However, the effectiveness of green finance may be influenc...
LCC TENDOkVudmlyb25tZW50YWwgc2NpZW5jZXM~Idioma eng
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The lipid–inflammation axis in rosacea: mechanistic insights and therapeutic implications
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The lipid–inflammation axis in rosacea: mechanistic insights and therapeutic implications
Xiaoyu Zhang et al · Frontiers Media S.A · 2026 · ISSN 1664-3224
Rosacea is a chronic inflammatory skin disorder primarily characterized by persistent facial erythema, episodic flushing, papules and pustules, as well as phymatous changes. Despite extensive research, the pathogenesis o...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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The performance ceiling: why clinical data is insufficient for precision prognosis in concussion
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The performance ceiling: why clinical data is insufficient for precision prognosis in concussion
Zach Napora et al · Frontiers Media S.A · 2026 · ISSN 1664-2295
The transition to active rehabilitation in concussion care requires precise tools to identify patients at risk of persistent post-concussive symptoms (PPCS). While machine learning (ML) offers the potential to personaliz...
LCC LCC:Neurology. Diseases of the nervous systemIdioma eng
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The risk of neoplasms in appendiceal abscess: what emergency surgeons should know
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The risk of neoplasms in appendiceal abscess: what emergency surgeons should know
Giulia Montori et al · Frontiers Media S.A · 2026 · ISSN 2234-943X
IntroductionA subset of patients with acute appendicitis presents with complicated disease characterized by periappendiceal abscess. Although appendiceal neoplasms are rare in uncomplicated appendicitis, recent evidence ...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Tools of the trade: leveraging 3D in vitro models to advance silicosis research
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Tools of the trade: leveraging 3D in vitro models to advance silicosis research
Ellen Donohoe et al · Frontiers Media S.A · 2026 · ISSN 1663-9812
Silicosis is an occupational fibrotic lung disease representing a major public health crisis, and places a significant burden on patients and healthcare systems. There are no curative treatments for patients with silicos...
LCC LCC:Therapeutics. PharmacologyIdioma eng
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