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BackgroundMetabolic syndrome (MetS) affects approximately 1.54 billion adults worldwide and is characterized by central obesity, insulin resistance, hypertension, and dyslipidemia. Chronic low-grade inflammation is cen...

AIM: The hepatitis B infection is a subject that still keeps its significance for hemodialysis staff members and hemodialysis patients at present. In this study, our aim was to evaluate whether the infections occurring d...

Galectins, a family of animal lectins, play central roles in immune system regulation, shaping both innate and adaptive responses in physiological and pathological processes. These include rheumatoid arthritis (RA), a ch...

Mehmet Zafer Aydın,1 Can Baba Arin,2 Mehmet Kamil Teber,1 Zülfiye Kuzu,1 Mustafa Gök,1 Ishak Ahmed Abdi3 1Department of Cardiology, Kayseri City Training and Research Hospital, Kayseri, Turkey; 2Department o...

OBJECTIVE: There is little knowledge on the differences between PD or HD initiation in terms of early and late morbidity and other complications. We aimed to compare the effect of different dialysis modalities on inflamm...

BackgroundAn adverse female bias exists across many autoimmune disorders, yet its underlying mechanisms, particularly the role of sex hormones, remain poorly understood. Furthermore, the physiological influence of sex ho...

OBJECTIVE: Central venous catheters (CVCs) are preferred when a patent arteriovenous fistula (AVF) cannot be created. CVCs have been shown to be associated with increased inflammation and mortality. In the present study,...

Hemozoin (Hz) is a crystalline by-product, which is produced when the Plasmodium species destroy haemoglobin, and it is commonly recognised that it leads to how our bodies respond to malaria. Although we understand prett...

BackgroundAs markers of inflammation and oxidative stress, immune cells and high-density lipoprotein cholesterol (HDL-c) derivative markers, such as the monocyte to HDL-c ratio (MHR) and lymphocyte to HDL-c ratio (LHR), ...

Autism spectrum disorder (ASD) exhibits a gender bias, with boys more frequently affected than girls. Similarly, in mouse models induced by prenatal exposure to valproic acid (VPA), males typically display reduced sociab...

BackgroundRecessive dystrophic epidermolysis bullosa (RDEB) is a devastating genodermatosis caused by biallelic COL7A1 mutations, where chronic inflammation drives disabling complications affecting quality of life and su...

Exposure to ambient air particulate matter (PM) is associated with increased cardiorespiratory morbidity and mortality. In this context, alveolar macrophages exhibit proinflammatory and oxidative responses as a result of...

This study tries to elucidate the mechanisms by which fructose rich diets (FRD) inhibit the rat intestinal Ca2+ absorption, and determine if any or all underlying alterations are prevented by naringin (NAR). Male rats we...

BackgroundSleep disruption(SD) has been shown to amplify inflammatory signaling and promote pain hypersensitivity, but how inflammation interacts with brain functional alterations to drive pain sensitization remains uncl...

OBJETIVO: avaliar a frequência de células da junção escamo-colunar (JEC) em esfregaços cérvico-vaginais de mulheres com 40 anos ou mais. MÉTODOS: foi realizado um estudo retrospectivo, com revisão de 24.316 laudo...

Substantial efforts have been made to understand the immune response during severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, in order to identify and characterize risk factors, immune mechanisms re...

OBJECTIVE: Vascular calcifications and chronic inflammation are the main reasons of the decreased life span and prevalent morbidity for patients on renal replacement therapy due to chronic renal failure. Scoring systems ...

Abstract Objective: Included evaluation of the possibility of using the systemic inflammatory indices for preoperative screening for the presence and severity of endometriosis (EM) in comparison to the findings of the e...

ABSTRACT Background and Aim Post‐acute sequelae of SARS‐CoV‐2 infection (PASC), commonly referred to as long COVID, has emerged as a significant global health concern, marked by persistent symptoms and chronic infl...

Abstract Background Chronic inflammatory disease is responsible for huge and increasing global mortality and morbidity. Unregulated inflammatory cells, including neutrophils and macrophages, are major drivers of chronic ...

OBJECTIVES: Global hypertension prevalence is increasing. Studies of the association of shift work with hypertension have produced inconsistent results, and the role of immune-inflammatory indices in this link remains un...

Abstract Background Cisplatin (CIS) is a chemotherapeutic agent which is frequently utilised in the treatment of ovarian, breast, testicular and lung cancer. Nevertheless, the potential for severe and irreversible toxici...

Abstract Background and hypothesis CD5L is a glycoprotein induced during inflammation and makes a life-saving contribution in infection and sepsis. Here, we explored the immunomodulatory effect of CD5L in rheumatoid arth...

Severe gingival inflammation, which is uncommon in pediatric patients, often indicates underlying systemic conditions. Leukemia, autoimmune diseases, and allergic symptoms can cause gingivitis owing to systemic inflammat...