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Tuberculosis (TB) is one of the most prevalent infectious diseases worldwide. However, few molecules related to bacterial killing within T cell-induced macrophages are known; therefore, elucidating host responses against...

Lassa fever is a zoonotic disease endemic to several West African countries, with seasonal outbreaks and potential to cause future epidemics. Vaccines and other medical countermeasures are in development, requiring relia...

The gut microbiota plays a central role in modulating both immunity and metabolism. Obesity-associated microbiota configuration is a critical driver of persistent inflammatory activation and immune dysfunction, ultimatel...

Background & aims Proton pump inhibitor (PPI) use has been associated with metabolic dysfunction associated with steatotic liver disease (MASLD) in multiple studies. While the association is confounded by various risk fa...

Materias / palabras clave: Hepatitis B; functional cure; anti-HBs; Peg-IFNα; vaccination

Microbial siderophores are low-molecular-weight compounds with a strong affinity for ferric (FSe3+) ions. They play a pivotal role in plant-microbial interactions by enhancing iron bioavailability to plants, primarily th...

Mitochondria are vital for maintaining cellular homeostasis. However, mitochondrial damage is evident in patients with chronic hepatitis B (CHB). The role of mitochondrial dysfunction in the persistence of viral replicat...

Mixed infection refers to the presence of multiple Mycobacterium tuberculosis strains within one host, while heteroresistance denotes the coexistence of drug-susceptible and drug-resistant strains or genotypes. Mixed inf...

Recent studies have shown that the presence of an RNA modification, N6-methyladenosine (m6A), in viral RNAs during infection significantly impacts the outcome of viral replication and pathogenesis. In particular, various...

Las especias son utilizadas en los alimentos desde hace cientos de años. En la actualidad, sus aceites esenciales y oleorresinas se utilizan no solo como saborizantes y aromatizantes sino también como conservantes d...

Soil microbes are the driving force behind soil nutrient cycling, yet the role of their composition and function in controlling forest nutrient cycling is poorly understood and rarely used to predict rates of biogeochemi...

To understand the impact of gut microbes on human health and well-being it is crucial to assess their genetic potential. Here we describe the Illumina-based metagenomic sequencing, assembly and characterization of 3.3 mi...

BACKGROUND: We recently described FastTree, a tool for inferring phylogenies for alignments with up to hundreds of thousands of sequences. Here, we describe improvements to FastTree that improve its accuracy without sacr...

This updated and expanded edition now offers 297 chapters that cover the basic principles of diagnosis and management, major clinical syndromes, all important pathogenic microbes and the diseases they cause, plus a numbe...

Studies of the human microbiome have revealed that even healthy individuals differ remarkably in the microbes that occupy habitats such as the gut, skin and vagina. Much of this diversity remains unexplained, although di...

Materias / palabras clave: horticulturae, plants, animals, microbes, biology, life sciences; Science: Botany: Plant ecology; Science: Physiology: Animal biochemistry; Science: Biology (General)

Materias / palabras clave: biosciences, biodiversity, microbes, fungi, plants, animals; Science: Biology (General)