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BackgroundDominant-negative (DN) STAT3 defects (STAT3-DN) result in >75% loss of STAT3 function and lead to autosomal-dominant hyper-IgE syndrome (HIES) characterized by severe eczema, recurrent bacterial and fungal infe...

Factor analysis, path analysis, structural equation modeling, and related multivariate statistical methods are based on maximum likelihood or generalized least squares estimation developed for covariance structure models...

Abstract This paper develops a new approach to the problem of testing the existence of a level relationship between a dependent variable and a set of regressors, when it is not known with certainty whether the underlying...

Introduction Interactions between Continuous Predictors in Multiple Regression The Effects of Predictor Scaling on Coefficients of Regression Equations Testing and Probing Three-Way Interactions Structuring Regression Eq...

An essential textbook for any student or researcher in biology needing to design experiments, sample programs or analyse the resulting data. The text begins with a revision of estimation and hypothesis testing methods, c...

With its theoretical basis firmly established in molecular evolutionary and population genetics, the comparative DNA and protein sequence analysis plays a central role in reconstructing the evolutionary histories of spec...

A framework for hypothesis testing and power analysis in the assessment of fit of covariance structure models is presented. We emphasize the value of confidence intervals for fit indices, and we stress the relationship o...

BACKGROUND: the analysis of microbial communities through dna sequencing brings many challenges: the integration of different types of data with methods from ecology, genetics, phylogenetics, multivariate statistics, vis...

Abstract Hypothesis‐testing methods for multivariate data are needed to make rigorous probability statements about the effects of factors and their interactions in experiments. Analysis of variance is particularly powe...

Preface to the Third Edition.Preface to the Second Edition.Preface to the First Edition.1. Introduction.2. The Multivariate Normal Distribution.3. Estimation of the Mean Vector and the Covariance Matrix.4. The Distributi...

In this article, we provide guidance for substantive researchers on the use of structural equation modeling in practice for theory testing and development. We present a comprehensive, two-step modeling approach that empl...

Collinearity refers to the non independence of predictor variables, usually in a regression‐type analysis. It is a common feature of any descriptive ecological data set and can be a problem for parameter estimation bec...

Abstract Measurement invariance is usually tested using Multigroup Confirmatory Factor Analysis, which examines the change in the goodness-of-fit index (GFI) when cross-group constraints are imposed on a measurement mode...

Contents: Part I: Introduction. Structural Equation Models: The Basics. Using the EQS Program. Part II: Single-Group Analyses. Application 1: Testing for the Factorial Validity of a Theoretical Construct (First-Order CFA...

The history of the development of statistical hypothesis testing in time series analysis is reviewed briefly and it is pointed out that the hypothesis testing procedure is not adequately defined as the procedure for stat...

Se describe un método para operar con material vegetal, utilizable sistemáticamente en su extracción y fraccionamiento y en la vehiculización de extractos, fracciones y sustancias aisladas. El método de extracción ...

Los análisis de Fourier permiten caracterizar el contorno del diente a partir de un número determinado de puntos y extraer una serie de parámetros para un posterior análisis multivariante. No obstante, la gran comple...

"Penetration Testing (short pentesting) is a methodology for assessing network security, by generating and executing possible attacks exploiting known vulnerabilities of operating systems and applications. Doing so autom...

Over the last 20 years, Bulk Current Injection (BCI) testing has become increasingly critical for assessing the electromagnetic compatibility (EMC) of integrated circuits (ICs) in automotive applications. This PhD thesis...

This thesis aims to develop a model for an industrial evaporative cooling system having a chiller and a production heat source using two cooling towers to evaluate the energy consumption of the system and find an optimal...

"This thesis aims to develop a model for an industrial evaporative cooling system having a chiller and a production heat source using two cooling towers, to evaluate the energy consumption of the system and find an optim...

Medical educators attempt to create reliable and valid tests and questionnaires in order to enhance the accuracy of their assessment and evaluations. Validity and reliability are two fundamental elements in the evaluatio...

Diagnostic systems of several kinds are used to distinguish between two classes of events, essentially "signals" and "noise". For them, analysis in terms of the "relative operating characteristic" of signal detection the...