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Abstract Two (male and female) 10‐month‐old American Staffordshire Terrier littermates presented for progressive weakness, joint contracture, and distal limb joint hyperlaxity beginning around 6 months of age. Neur...

Abstract Background The global rise of multidrug-resistant Enterobacterales, particularly extended-spectrum beta-lactamase (ESBL)- and carbapenemase-producing Escherichia coli and Klebsiella pneumoniae, poses a critical ...

Abstract Background The prevalence of clinical signs and factors triggering muscle atrophy and rhabdomyolysis associated with an MYH1E321G mutation in Quarter Horses and related breeds (QH) remain poorly understood. Hypo...

Abstract In order to develop high yielding wheat genotypes resistant to yellow rust, marker-assisted selection (MAS) was utilized. The hard red spring wheat line Lassik was used as a donor, carrying three genes: high tem...

BackgroundComplex inflammatory phenotypes in children can pose significant diagnostic challenges, particularly when clinical, histopathologic, and immunologic findings do not conform to established diagnoses. We present ...

Providing feed is a major input cost in beef production, hence improvements in the efficiency of feed utilisation will reduce the cost of production. Residual feed intake (RFI) is a measure of feed efficiency, and is def...

Abstract Cis-acting regulatory enhancer elements are powerful tools for achieving cell type-specific genetic access in adeno-associated virus (AAV) delivery platforms. However, a significant bottleneck in enhancer discov...

Abstract Objective To explore the utility of microarray technology in prenatal diagnosis of nasal bone agenesis or hypoplasia. Methods Between July 2018 to October 2023, several cases of abnormal nasal bone development w...

Abstract Background Accurate risk stratification of colorectal cancer (CRC) is essential for precise screening. Polygenic risk scores (PRS) hold promise for improving predictive efficacy in CRC. However, the real-world a...

Materias / palabras clave: Medical genetics; Workgroup; Exome sequencing; Context (archaeology); Exome; Genomics; Genetic testing; Genetics; Whole genome sequencing; Genetic association; Computational biology; Biology

As a new promising crossover method, multiple crossovers per couple (MCPC) deserves special attention in evolutionary computing field. Allowing multiple crossovers per couple on a selected pair of parents provided an ext...

With its theoretical basis firmly established in molecular evolutionary and population genetics, the comparative DNA and protein sequence analysis plays a central role in reconstructing the evolutionary histories of spec...

We announce the release of the fourth version of MEGA software, which expands on the existing facilities for editing DNA sequence data from autosequencers, mining Web-databases, performing automatic and manual sequence a...

The relationship between the two estimates of genetic variation at the DNA level, namely the number of segregating sites and the average number of nucleotide differences estimated from pairwise comparison, is investigate...

Migration of individuals allows a fruitful interaction between subpopulations in the island model, a well known distributed approach for evolutionary computing, where separate subpopulations evolve in parallel. This mode...

Non-stationary, or dynamic, problems change over time. There exist a variety of forms of dynamism. The concept of dynamic environments in the context of this paper means that the fitness landscape changes during the run...

MOTIVATION: Chimeric DNA sequences often form during polymerase chain reaction amplification, especially when sequencing single regions (e.g. 16S rRNA or fungal Internal Transcribed Spacer) to assess diversity or compare...

Mobile robot's navigation and obstacle avoidance in an unknown and static environment is analyzed in this paper. From the guidance of position sensors, artificial neural network (ANN) based controllers settle the desired...

The traditional view of colonization of the Americas as a migration across Beringia and subsequent dispersal southward following the last glacial maximum is being increasingly questioned. In North America, archaeological...

Abstract In a 1935 paper and in his book Theory of Probability, Jeffreys developed a methodology for quantifying the evidence in favor of a scientific theory. The centerpiece was a number, now called the Bayes factor, wh...

Materias / palabras clave: public health genetics, genetic counceling, implementation science, elsi, genetic testing, community engagement; Medicine: Public aspects of medicine; Science: Biology (General): Genetics