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Abstract Background Ophiocordyceps sinensis is a premier medicinal fungus with a unique slow-killing parasitic strategy, yet the molecular basis of its long-term persistence in host hemocoel remains elusive. This fungus ...

Introduction Lung cancer (LC) is the leading cause of cancer-related mortality worldwide, primarily due to diagnosis at advanced stages. Although low-dose computed tomography (LDCT) screening reduces lung cancer mortalit...

Hepatic manifestations of type 2 diabetes, including steatosis, represent a major complication driven by hepatic lipotoxicity and ceramide accumulation, yet few targeted interventions are available. This study investigat...

Abstract Recent advancements in single-cell DNA methylation (scDNAm) sequencing technologies have enabled the profiling of epigenetic landscapes at unprecedented resolution, offering insights into cellular heterogeneity,...

Resolving the molecular details of proteome variation in the different tissues and organs of the human body will greatly increase our knowledge of human biology and disease. Here, we present a map of the human tissue pro...

Increasing quantitative data generated from transcriptomics and proteomics require integrative strategies for analysis. Here, we present an R package, clusterProfiler that automates the process of biological-term classif...

Tesis de Doctorado El bloqueo de los puntos de control como CTLA-4 y PD-1/PD-L1 ha demostrado la actividad de efectores inmunes antitumorales, por lo que ha aumentado el interés en el desarrollo de inmunoterapias contra...

A critical component in the interpretation of systems-level studies is the inference of enriched biological pathways and protein complexes contained within OMICs datasets. Successful analysis requires the integration of ...

Materias / palabras clave: disease-specific biomarkers, omics science, bioinformatics, applied immunology, molecular medicine; Medicine: Medicine (General)

Materias / palabras clave: crop improvement, plant biotechnology, multi-omics technologies, crop protection & abiotic atress, computational biology & artificial intelligence; Agriculture: Agriculture (General); Technology: Chemical technology: Bio...

Materias / palabras clave: infectious disease, pathogen, epidemiology, omics, public health, zoonosis; Medicine: Internal medicine: Infectious and parasitic diseases

Materias / palabras clave: chemometrics, environmental analysis, forensic chemistry, omics, pharmaceutical analysis, biomedical analysis; Science: Chemistry: Analytical chemistry

Materias / palabras clave: genetics, genomics, multi-omics, precision medicine, systems medicine; Medicine; Science: Biology (General): Genetics

Materias / palabras clave: computer science, omics, software tools, computational methods, datasets; Science: Mathematics: Instruments and machines: Electronic computers. Computer science

Materias / palabras clave: genetics, gene therapy, cell biology, pediatrics, heredity, omics; Science: Biology (General): Genetics; Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens

Materias / palabras clave: biomarker, molecular docking, virtual twin, omics, molecular dynamics, biomedicine; Medicine: Medicine (General): Computer applications to medicine. Medical informatics

Materias / palabras clave: clinical applicability of new biomaterials, omics science, biotechnologies, molecular imaging, drug discovery and development, cardiovascular disease; Medicine: Medicine (General): Computer applications to medicine. Medi...

Materias / palabras clave: adult oncology, amyloidosis, basic and translational research, genetics, omics and tissue regeneration, health promotion and preventive cardiology; Medicine: Internal medicine: Specialties of internal medicine: Diseases ...

Materias / palabras clave: biomedical sciences, life sciences, genomics, transcriptomics, proteomics, omics; Medicine; Science: Biology (General)

Materias / palabras clave: bioinformatics, omics, extracellular nucleic acids, liquid biopsy; Science: Biology (General); Medicine

Materias / palabras clave: microbiome, meta-omics, bioinformatics, metagenomics; Medicine: Medicine (General): Computer applications to medicine. Medical informatics