NODOVOX | Discovery

Testing interventions to increase participation in the Australian National Bowel Cancer Screening Program among persistent never-screeners: study protocol for a randomised controlled trial

Artículo

Acceso abierto Artículo DOAJ

Testing interventions to increase participation in the Australian National Bowel Cancer Screening Program among persistent never-screeners: study protocol for a randomised controlled trial

Jennifer G McIntosh et al · BMC · 2026 · ISSN 1745-6215

Abstract Background Bowel cancer screening using faecal immunochemical tests (FIT) can detect early signs of bowel cancer and pre-cancerous adenoma. Early detection enables early diagnosis and treatment thereby reducing ...

LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng

Acceso abiertoRuta libre sin proxy. Acceso recomendado cuando no hay suscripción activa.

Open Access

Disponible en línea Ficha bibliográfica

Macrophage-derived legumain ameliorates excessive mechanical stress-induced ferroptosis of nucleus pulposus cells and intervertebral disc degeneration via integrin αvβ3–Hippo signaling

Artículo

Material complementario disponible Artículo DOAJ

Macrophage-derived legumain ameliorates excessive mechanical stress-induced ferroptosis of nucleus pulposus cells and intervertebral disc degeneration via integrin αvβ3–Hippo signaling

Peiyang Wang et al · BMC · 2026 · ISSN 1689-1392

Abstract Background Excessive mechanical stress is a major cause of intervertebral disc degeneration (IVDD). Macrophages can sense physical signals, but their role in responding to mechanical stress within the disc to ma...

LCC LCC:CytologyIdioma eng

Material complementario disponibleEl enlace apunta a material asociado, anexos, tablas, datos o página complementaria. No se marca como libro/texto completo.

Material complementario

Abrir material Ficha bibliográfica

Combination of Tripterygium glycosides and Lactobacillus paracasei sensitises epithelial ovarian cancer to cisplatin via downregulating Keap1-Nrf2-GPX4 signalling pathway

Artículo

Material complementario disponible Artículo DOAJ

Combination of Tripterygium glycosides and Lactobacillus paracasei sensitises epithelial ovarian cancer to cisplatin via downregulating Keap1-Nrf2-GPX4 signalling pathway

Meiyun Tian et al · BMC · 2026 · ISSN 1689-1392

Abstract Background Epithelial ovarian cancer (EOC) is a highly heterogeneous malignancy with significant morbidity and mortality, and cisplatin (DDP) resistance remains a major obstacle in its treatment. Previous studie...

LCC LCC:CytologyIdioma eng

Material complementario disponibleEl enlace apunta a material asociado, anexos, tablas, datos o página complementaria. No se marca como libro/texto completo.

Material complementario

Abrir material Ficha bibliográfica

Intermittent fasting inhibits ferroptosis by modulating CD36 and its palmitoylation to alleviate diabetic dry eye

Artículo

Material complementario disponible Artículo DOAJ

Intermittent fasting inhibits ferroptosis by modulating CD36 and its palmitoylation to alleviate diabetic dry eye

Wenhui Wang et al · BMC · 2026 · ISSN 1689-1392

Abstract Background Excessive lipid accumulation in the lacrimal glands under diabetic conditions can lead to lacrimal gland dysfunction and reduced tear secretion, subsequently resulting in ocular surface inflammation, ...

LCC LCC:CytologyIdioma eng

Material complementario disponibleEl enlace apunta a material asociado, anexos, tablas, datos o página complementaria. No se marca como libro/texto completo.

Material complementario

Abrir material Ficha bibliográfica

STUB1 downregulates TOP2A through a dual mechanism of ubiquitination and FOXM1-mediated transcription repression, suppressing breast cancer growth and enhancing sensitivity to chemotherapy

Artículo

Acceso abierto Artículo DOAJ

STUB1 downregulates TOP2A through a dual mechanism of ubiquitination and FOXM1-mediated transcription repression, suppressing breast cancer growth and enhancing sensitivity to chemotherapy

Baohui Yue et al · BMC · 2026 · ISSN 1689-1392

Abstract Background DNA topoisomerase IIɑ (TOP2A) is crucial for maintaining genomic stability and is an important target for genotoxic chemotherapeutic drugs. STIP1 homology and U-box-containing protein 1 (STUB1) is a ...

LCC LCC:CytologyIdioma eng

Acceso abiertoRuta libre sin proxy. Acceso recomendado cuando no hay suscripción activa.

Open Access

Disponible en línea Ficha bibliográfica

Targeting dormant cancer cells: ferroptosis as a precision therapeutic strategy

Artículo

Material complementario disponible Artículo DOAJ

Targeting dormant cancer cells: ferroptosis as a precision therapeutic strategy

Sijia Hao et al · BMC · 2026 · ISSN 1689-1392

Abstract Dormant cancer cells are a significant source of cancer recurrence and metastasis and exhibit robust resistance to conventional therapies. Therefore, the exploration of novel therapeutic strategies to eliminate ...

LCC LCC:CytologyIdioma eng

Material complementario disponibleEl enlace apunta a material asociado, anexos, tablas, datos o página complementaria. No se marca como libro/texto completo.

Material complementario

Abrir material Ficha bibliográfica

Therapeutic potential of 20-Hydroxyecdysone in pulmonary arterial hypertension: involvement of Mas receptor and PI3K–Akt pathway

Artículo

Acceso abierto Artículo DOAJ

Therapeutic potential of 20-Hydroxyecdysone in pulmonary arterial hypertension: involvement of Mas receptor and PI3K–Akt pathway

Tong Lu et al · BMC · 2026 · ISSN 1689-1392

Abstract Background 20-Hydroxyecdysone (20E), a natural polyhydroxylated steroid found in various edible plants, exhibits diverse pharmacological effects. Pulmonary arterial hypertension (PAH) remains challenging to trea...

LCC LCC:CytologyIdioma eng

Acceso abiertoRuta libre sin proxy. Acceso recomendado cuando no hay suscripción activa.

Open Access

Disponible en línea Ficha bibliográfica

Vertebrate-wide transcriptomic screening identifies immune cell-specific expression of the conserved OR-κ gene

Artículo

Material complementario disponible Artículo DOAJ

Vertebrate-wide transcriptomic screening identifies immune cell-specific expression of the conserved OR-κ gene

Kanoko Nishiura et al · BMC · 2026 · ISSN 2056-306X

Abstract Vertebrate chemoreceptor genes play a central role in detecting environmental chemical compounds through the olfactory organs and taste buds, enabling the perception of odors and tastants that are critical for s...

LCC TENDOlpvb2xvZ3k~Idioma eng

Material complementario disponibleEl enlace apunta a material asociado, anexos, tablas, datos o página complementaria. No se marca como libro/texto completo.

Material complementario

Abrir material Ficha bibliográfica

Fluocinolone acetonide implant in diabetic macular edema: sustained benefits and effects of following prior therapy

Artículo

Material complementario disponible Artículo DOAJ

Fluocinolone acetonide implant in diabetic macular edema: sustained benefits and effects of following prior therapy

Philipp Necpal et al · BMC · 2026 · ISSN 2056-9920

Abstract Purpose To (1) evaluate long-term real-world anatomical and functional outcomes after implantation of a sustained-release fluocinolone acetonide (FAc) implant in eyes with diabetic macular edema (DME) and (2) to...

LCC TENDOk9waHRoYWxtb2xvZ3k~Idioma eng

Material complementario disponibleEl enlace apunta a material asociado, anexos, tablas, datos o página complementaria. No se marca como libro/texto completo.

Material complementario

Abrir material Ficha bibliográfica

Buscar recursos académicos

Resultados