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Abstract Background The efficacy of conventional αβ T cell-based immunotherapies is often limited by tumor immune evasion. γδ T cells can bypass these limitations through MHC-independent tumor recognition, but their ...

Abstract Medical images are inherently high-resolution and contain locally varying structures that are crucial for diagnosis. Efficient compression of such data must therefore preserve diagnostic fidelity while minimizin...

Abstract Background Implementation climate is a key organizational determinant of whether evidence-based interventions (EBIs) are adopted, delivered with fidelity, and sustained in healthcare. Despite its importance, the...

Abstract Introduction Across the globe, traditional medicine, particularly herbal remedies, is a cornerstone of healthcare. While the medicinal uses of ferns are widely recognized globally, their therapeutic potential in...

Abstract Background Safe anesthesia is fundamental to safe surgery and depends on facility readiness, team behaviors, and consistent adherence to safety standards such as the World Health Organization (WHO) Surgical Safe...

Abstract Background Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) protein profiling has emerged over the last decade as a method of choice for species identification of many ...

Abstract Background Lung cancer stigma (i.e., perceived and internalized negative appraisal and devaluation associated with lung cancer) is a clinically significant psychosocial concern among individuals diagnosed with l...

Abstract Periodontitis and dental caries are the most widespread non-communicable oral disorders worldwide, affecting approximately 3.5 billion people worldwide. Nevertheless, existing in vitro models do not accurately ...

Abstract Dysregulated expression of tumor suppressor genes can impair their functions, even promoting oncogenesis. Expression of p53β mRNA can be regulated by alternative splicing and RNA surveillance, otherwise transla...

Abstract Background High-fidelity simulation is a cornerstone of emergency medicine (EM) education and is used by a majority of EM clerkships. Traditional high-fidelity simulation involves learners working through a pred...

Abstract Background Fatigue is the main complaint of 5–10% of patients in primary care and is often associated with significant suffering and functional disability. Cognitive behavioral therapy (CBT) has demonstrated e...

Abstract Objective Occupational exposure to ionizing radiation is a known risk factor for genomic instability. This study evaluated whether physicians occupationally exposed to ionizing radiation exhibit higher frequenci...