NODOVOX | Discovery

N-terminally acetylated Met11-Tau: a new pathological truncated Tau species with functional relevance in Alzheimer's disease

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N-terminally acetylated Met11-Tau: a new pathological truncated Tau species with functional relevance in Alzheimer's disease

Sarah Guedjdal et al · BMC · 2026 · ISSN 2047-9158

Abstract Background Tauopathies are a group of neurodegenerative diseases, including Alzheimer’s disease (AD), characterized by progressive accumulation of pathological Tau proteins. Among the diverse Tau species, trun...

LCC LCC:Neurology. Diseases of the nervous systemIdioma eng

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A 57-year-old male with diffuse astrocytoma in the lateral ventricle: case report

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A 57-year-old male with diffuse astrocytoma in the lateral ventricle: case report

Juan Wang et al · BMC · 2026 · ISSN 1471-2377

Abstract Background Diffuse astrocytoma (DA) is the most common intraparenchymal brain tumor, primarily occurring in the frontal and temporal lobes. However, its occurrence in the lateral ventricles is rare. Case present...

LCC LCC:Neurology. Diseases of the nervous systemIdioma eng

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A retrospective analysis of risk-reducing salpingo-oophorectomy performed in women diagnosed with hereditary breast and ovarian cancer at our institution

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A retrospective analysis of risk-reducing salpingo-oophorectomy performed in women diagnosed with hereditary breast and ovarian cancer at our institution

Yusaku Shimizu et al · BMC · 2026 · ISSN 1897-4287

Abstract Background Hereditary breast and ovarian cancer (HBOC) confers a markedly increased lifetime risk of breast and ovarian cancers. As no effective surveillance method for early detection of ovarian cancer has been...

LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~; LCC:GeneticsIdioma eng

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Impact of combined vascular resection on short and long-term results following radical surgery for hilar cholangiocarcinoma: evidence from a systematic assessment

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Impact of combined vascular resection on short and long-term results following radical surgery for hilar cholangiocarcinoma: evidence from a systematic assessment

Sihan Che et al · BMC · 2026 · ISSN 1477-7819

Abstract Objective To analyze the impact of portal vein resection (PVR) and hepatic artery resection (HAR) on the short-term and long-term outcomes of patients with hilar cholangiocarcinoma after surgery. Methods A compr...

LCC TENDOlN1cmdlcnk~; TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng

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Presenilin-dependent regulation of neuronal tau pathology via the autophagy and proteasome pathways

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Presenilin-dependent regulation of neuronal tau pathology via the autophagy and proteasome pathways

Anna del Ser-Badia et al · BMC · 2026 · ISSN 2051-5960

Abstract Mutations in the presenilin (PS/PSEN) genes cause early-onset familial Alzheimer’s disease (AD) by enhancing cerebral accumulation of amyloid-β (Aβ) peptides and microtubule-associated protein tau (MAPT). Ho...

LCC LCC:Neurology. Diseases of the nervous systemIdioma eng

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Stromal hypoxia and autophagy signatures as indicators of pathologic response in triple-negative breast cancer

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Stromal hypoxia and autophagy signatures as indicators of pathologic response in triple-negative breast cancer

Hanife Seda Mavili et al · BMC · 2026 · ISSN 1471-2407

Abstract Background Triple-negative breast cancer (TNBC) is an aggressive subtype with limited therapeutic targets. Hypoxia, autophagy, apoptosis, and translational stress are key biological processes involved in tumor p...

LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng

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The influence of postoperative risk factors on patient survival and lymph node metastasis in cervical squamous cell carcinoma

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The influence of postoperative risk factors on patient survival and lymph node metastasis in cervical squamous cell carcinoma

Xuerong Wang et al · BMC · 2026 · ISSN 1471-2407

Abstract Objective To investigate the influence of postoperative pathological factors (including variables not categorized as moderate - to - high - risk factors according to the Sedlis criteria) on the prognosis and lym...

LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng

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