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12 resultados encontrados.

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Prediction and monitoring of accrual and rate of underrepresented biomedical research group using bayesian methods
Artículo
Material complementario disponible Artículo DOAJ
Prediction and monitoring of accrual and rate of underrepresented biomedical research group using bayesian methods
Kaustubh S. Nimkar et al · BMC · 2026 · ISSN 1471-2288
Abstract Background There has been a recent push for biomedical research to incorporate more demographically, ethnically, and medically diverse cohorts – individuals whom the NIH designates as “underrepresented in bi...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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Centers performance for end-stage kidney replacement therapy: a Bayesian hierarchical logistic regression for a binary kidney transplant status
Artículo
Material complementario disponible Artículo DOAJ
Centers performance for end-stage kidney replacement therapy: a Bayesian hierarchical logistic regression for a binary kidney transplant status
Solomon Woldeyohannes et al · BMC · 2026 · ISSN 1471-2288
Abstract Purpose The past two decades witnessed increased use of risk-adjusted standardized measures such as standardized mortality ratios (SMRs) and standardized incidence ratios (SIRs) in institutional comparisons betw...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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Comparative evaluation of Bayesian external information borrowing and frequentist approaches in underpowered confirmatory trials
Artículo
Material complementario disponible Artículo DOAJ
Comparative evaluation of Bayesian external information borrowing and frequentist approaches in underpowered confirmatory trials
Ruobing Li et al · BMC · 2026 · ISSN 1471-2288
Abstract The application of Bayesian statistics in pivotal clinical trials has gained increasing attention, particularly for underpowered confirmatory trials such as those in pediatric and rare disease populations. Bayes...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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A comparison and evaluation of statistical methods for mediation analysis with mixtures of environmental exposures
Artículo
Acceso abierto Artículo DOAJ
A comparison and evaluation of statistical methods for mediation analysis with mixtures of environmental exposures
Sean McGrath et al · BMC · 2026 · ISSN 1471-2288
Abstract Background Environmental studies often evaluate how exposures influence health outcomes through intermediate biological processes. In practice, researchers are often interested in complex exposure mixtures rathe...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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How can innovative trials in juvenile idiopathic arthritis serve the unmet needs of patients?
Artículo
Acceso abierto Artículo DOAJ
How can innovative trials in juvenile idiopathic arthritis serve the unmet needs of patients?
Joshua L Bennett et al · BMC · 2026 · ISSN 1478-6362
Abstract Juvenile idiopathic arthritis (JIA) comprises a heterogeneous group of childhood-onset inflammatory arthritides that remain challenging to treat. An expanding range of biologic and targeted synthetic disease-mod...
LCC LCC:Diseases of the musculoskeletal systemIdioma eng
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Causal inference and mediating pathways of metabolic syndrome on calcific aortic valve stenosis: linkage disequilibrium score regression and two-sample, two-step mendelian randomization study
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Causal inference and mediating pathways of metabolic syndrome on calcific aortic valve stenosis: linkage disequilibrium score regression and two-sample, two-step mendelian randomization study
Shu Yang et al · BMC · 2026 · ISSN 1749-8090
Abstract Background Current evidence regarding the role of Metabolic Syndrome (MetS) and its components in Calcific Aortic Valve Stenosis (CAVS) remains limited and inconsistent. To elucidate the causal relationship and ...
LCC TENDOlN1cmdlcnk~; LCC:AnesthesiologyIdioma eng
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Comparison of the diagnostic value of targeted next-generation sequencing, metagenomic next-generation sequencing, and Xpert MTB/RIF in adult pulmonary tuberculosis
Artículo
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Comparison of the diagnostic value of targeted next-generation sequencing, metagenomic next-generation sequencing, and Xpert MTB/RIF in adult pulmonary tuberculosis
Qiaoqian Chen et al · BMC · 2026 · ISSN 1471-2334
Abstract Tuberculosis (TB) has high morbidity and mortality rates, and drug-resistant strains pose an increasing challenge. Traditional methods for detecting the Mycobacterium tuberculosis complex (MTBC) are insufficient...
LCC TENDOkluZmVjdGlvdXMgYW5kIHBhcmFzaXRpYyBkaXNlYXNlcw~~Idioma eng
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Molecular network characteristics and transmissible drug resistance of HIV-1 CRF55_01B in Yunnan Province
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Molecular network characteristics and transmissible drug resistance of HIV-1 CRF55_01B in Yunnan Province
Yuan Li et al · BMC · 2026 · ISSN 1471-2334
Abstract Objective By using molecular network technology to analyze the transmission characteristics of the CRF55_01B strain in Yunnan Province, we aimed to identify high-risk transmitters, trace the origin time, locatio...
LCC TENDOkluZmVjdGlvdXMgYW5kIHBhcmFzaXRpYyBkaXNlYXNlcw~~Idioma eng
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Physical activity modalities and dosing for postpartum depression, anxiety and quality of life: a network meta-analysis and dose response of randomized trials
Artículo
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Physical activity modalities and dosing for postpartum depression, anxiety and quality of life: a network meta-analysis and dose response of randomized trials
Yanmei Wang et al · BMC · 2026 · ISSN 1471-2458
Abstract Background Postpartum depression and anxiety are common and burdensome. Physical activity (PA) is a scalable intervention, yet the comparative effectiveness of PA modalities and optimal dosing in the postpartum ...
LCC LCC:Public aspects of medicineIdioma eng
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Recall bias in population-based case-control studies of ovarian cancer and genital talcum powder use: potential impact and quantitative bias analysis
Artículo
Acceso abierto Artículo DOAJ
Recall bias in population-based case-control studies of ovarian cancer and genital talcum powder use: potential impact and quantitative bias analysis
Diezhang Wu et al · BMC · 2026 · ISSN 1471-2288
Abstract Introduction Quantitative bias analysis (QBA) methods have been developed, with growing applications to epidemiological studies. Bayesian QBA (BQBA) methods may be superior in effectively using evidence-based pr...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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Restless legs syndrome in children with celiac disease: associations with vitamin D and iron deficiency and the role of gluten-free diet adherence
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Restless legs syndrome in children with celiac disease: associations with vitamin D and iron deficiency and the role of gluten-free diet adherence
Ayşegül Cebe Tok et al · BMC · 2026 · ISSN 1471-2431
Abstract Background Celiac disease (CD) is a systemic autoimmune disorder frequently associated with micronutrient deficiencies and extraintestinal manifestations, including neurological complications. Restless Legs Synd...
LCC TENDOlBlZGlhdHJpY3M~Idioma eng
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The association of multiple whole blood metals with hypertension prevalence and blood pressure among general Chinese adults
Artículo
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The association of multiple whole blood metals with hypertension prevalence and blood pressure among general Chinese adults
Yurong Xiong et al · BMC · 2026 · ISSN 1475-2891
Abstract Background Epidemiological associations between multiple metals exposure and hypertension or blood pressure remain limited and inconclusive, especially for essential metals. This investigation intended to examin...
LCC LCC:Nutrition. Foods and food supply; LCC:Nutritional diseases. Deficiency diseasesIdioma eng
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