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Abstract Background Hereditary angioedema (HAE) is a rare, potentially life-threatening genetic disorder that is caused by C1-inhibitor (C1INH) deficiency or dysfunction. This scoping review sought to map recent advances...

Abstract Background Multimorbidity, defined as the coexistence of at least two chronic diseases in an individual, exhibits spatial heterogeneity in its association with lifestyle factors across different climatic zones. ...

Abstract Aim This study aimed to determine whether simulation training designed according to INACSL Standards improves satisfaction, self-confidence, and perceptions of simulation design and educational practices among m...

Abstract Background A conceptually guided framework examining how family communication relates to advance directive completion rates among older adults may offer useful insights for improving end-of-life decision-making ...

Abstract Polyunsaturated fatty acids (PUFAs) are important nutrients that play critical roles in sea urchin reproduction and early development. Strongylocentrotus intermedius, the only commercially cultured sea urchin sp...

Abstract Background Obesity is associated with metabolic dysfunction-associated steatotic liver disease (MASLD). Despite the rising prevalence of obesity among children and adolescents, no studies have examined risk fact...

Abstract Background Wilson disease (WD) is a rare inherited copper metabolism disorder with variable prevalence worldwide. Many regions lack reliable data, leading to underestimation of burden. WD presents with hepatic, ...

Abstract Background Health-related quality of life (HRQoL) in kidney transplant recipients (KTRs) is a key concern influenced by physiological, social, and cultural factors. However, yet commonly used assessment tools in...

Abstract Background Acute liver failure (ALF) is a life-threatening syndrome characterized by rapid deterioration of liver function, resulting in high mortality and posing a substantial global health burden. Human embryo...

Abstract Background The triglyceride-glucose (TyG) index has emerged as a surrogate marker for insulin resistance. This systematic review and meta-analysis of observational studies aimed to investigate the association be...