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Abstract Background Identification of disease-associated spectral alterations of oral squamous cell carcinoma (OSCC) and oral potentially malignant disorders (OPMD) is critical to improving patient outcomes. Protein stru...

Abstract Background Studies have shown that autophagy was closely involved in host defense against mycobacteria, and genetic variations in autophagy genes were related to susceptibility to multiple diseases. We conducted...

Abstract Background Early detection of renal involvement in ANCA-associated vasculitis (AAV) is crucial, as functional changes often precede anatomical damage. Current diagnostic standards, such as the measurement of ser...

Abstract Background Sudden Infant Death Syndrome (SIDS) remains a leading cause of infant mortality worldwide, yet its underlying mechanisms are largely unknown. SIDS etiology is complex and involves the interplay betwee...

Abstract Background Ischemic stroke (IS) remains a leading cause of death and disability worldwide. Stroke–heart syndrome, triggered by acute cerebral ischemia, causes autonomic dysfunction that can result in myocardia...

Abstract Objective Sickle cell anemia (SCA) is associated with substantial end‑organ morbidity, yet the circulating microRNA (miRNA) landscape in clinically stable, comorbidity‑free adults with SCA is poorly defined....

Abstract Background Altered pain processing and central sensitization are key mechanisms underlying migraine. Although quantitative sensory testing (QST) objectively assesses sensory thresholds, its clinical implications...

Abstract Background Immune tolerance breakdown at the maternal-fetal interface is implicated in unexplained recurrent pregnancy loss (URPL), but the interplay between T cell hyperactivation and dendritic cells (DCs)-medi...

Abstract Background Sleep impairment is common in ulcerative colitis (UC) and may persist during clinical remission. This study evaluated the clinical, inflammatory, metabolic, and behavioral features to better character...