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Abstract Humans are exposed to thousands of chemicals throughout their life. Many of these chemicals are detected in blood and have been catalogued in the Blood Exposome Database. Comprehensive hazard assessment of a che...

Abstract Purpose Fibromyalgia is a chronic pain syndrome characterized by central sensitization and frequent comorbidity clustering. Its impact on early readmission and procedural utilization during readmission after ele...

Abstract Background Adaptive designs (ADs) are increasingly used, whereby outcome data accumulated during the trial may inform a trial’s course in accordance with pre-specified rules at interim analyses. The benefits h...