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Abstract Background EUPATI Spain and EURORDIS have implemented a patient engagement model in health product research and development (R&D): international, independent Community Advisory Boards (CABs), where patients coll...

Abstract Polyunsaturated fatty acids (PUFAs) are important nutrients that play critical roles in sea urchin reproduction and early development. Strongylocentrotus intermedius, the only commercially cultured sea urchin sp...

Abstract Background The timing of puberty in offspring is influenced by various factors, including genetics and environment. While some studies suggest a link between parental age at childbirth and pubertal timing, the e...

Abstract Background Follicular development is a prerequisite for vertebrate reproduction, and it is precisely regulated by complex genomic conformations and regulatory elements. However, the dynamic changes in the intera...

Abstract Background The holistic health of children, encompassing physical, psychological, and social domains, plays a crucial role in long-term societal development. However, evidence suggests that many young people eng...

Abstract Background Numerous research studies indicate that Native Hawaiian and Pacific Islander (NHPI) youth report disproportionately higher substance use rates than other ethnic groups, as well as higher adverse effec...

Abstract Background Fear of falling (FOF) is a phenomenon prevalent among older adults associated with adverse outcomes, including reduced mental and physical health, decreased quality of life, and an overall reduction i...

Abstract Background Chronic conditions cause millions of deaths annually worldwide. Remote patient monitoring using wearable devices and sensors, combined with machine learning (ML), offers promising strategies for disea...

Abstract Background Nipple wounds are common complications during breastfeeding and may lead to pain, early cessation of breastfeeding, and maternal distress. Various pharmacological and non-pharmacological approaches ha...

Abstract Background Previous studies have indicated that chronic emotional stressors likely participate in the occurrence of cancers. However, direct evidence connecting stress and colorectal cancer development remains a...

Abstract Background Identification of risk and protective factors for canine visceral leishmaniasis (CVL) is essential to understand the epidemiology of the disease and direct prevention and control strategies. Building ...

Abstract Background Microglial activation is increasingly recognized as a critical contributor to both the initiation and chronification of migraine. Recent advances have highlighted the importance of receptor-mediated s...