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Abstract Background This study aims to establish the epidemiological and clinical Profile of viral hepatitis B and C (HBV and HCV) among adult patients attending the hepatitis clinic at Rwanda Military Referral and Teach...

Abstract Background Porcine circovirus type 2 (PCV2) and porcine circovirus type 3 (PCV3) have emerged as significant pathogens jeopardizing the swine industry in China in recent years, and caused substantial economic lo...

Abstract Background Acetabular fractures, predominantly caused by high-energy trauma, pose a substantial healthcare burden in low- and middle-income countries (LMICs) such as Nepal. This study aimed to characterize the e...

Abstract Background Recently, macrolide-resistant Bordetella pertussis (MRBP) had emerged in China. The aim of this study was to evaluate the prevalence and clinical characteristics of MRBP in Shenzhen, southern China. M...

Abstract Background Diarrhoeal diseases remain a major global health concern, particularly in low- and middle-income countries, contributing significantly to morbidity and mortality among children under five. This study ...

Abstract Background Malaria continues to pose a major public health challenge in sub-Saharan Africa (SSA), where more than 95% of global cases and deaths occur. Despite WHO Global Technical Strategy for Malaria (GTS) tar...

Abstract Background Antimicrobial resistance (AMR) represents a major global One Health challenge, with increasing recognition of the role of wildlife in the environmental circulation of resistant bacteria. Wild birds, p...

Abstract Background Malaria remains a major public health challenge in Benin, particularly among children under five years of age. Despite the wide deployment of vector control measures the disease burden remains high. B...

Abstract Background Xenomonitoring is an approach of epidemiological infection risk assessment addressing vector-transmitted infections like malaria in hematophagous arthropods. Standardization and automation can facilit...

Abstract Background Cardiogenic shock (CS) and Acute Renal Failure (ARF) have a compounding impact on patient survival. The long-term epidemiological burden of this cardiorenal comorbidity remains understudied despite th...

Abstract Background Most climate and health studies are based on a single extreme weather event and do not consider multiple physical processes across spatial and temporal scales. Our aim was to explore the current lands...

Abstract Background Leishmaniasis is a vector-borne disease caused by a protozoan parasite of the genus Leishmania. The infection is transmitted by the bite of infected female sandflies of the genus Phlebotomus in the Ol...

Abstract Background Recent reports documented catastrophic sensitivity failures (18%) of Abbott-Bioline™ Malaria Ag Pf/Pv rapid diagnostic tests (RDTs) at the Thailand-Myanmar border, prompting WHO to issue an informat...

Abstract Background Schistosomiasis due to the species Schistosoma intercalatum/guineensis, which had been traditionally classified as a single species, is one of the least studied. This work describes epidemiological, c...

Abstract Background Anthropogenic pressures, including urbanisation, globalisation and climate change, have facilitated an increased risk for emergence or re-emergence of mosquito-borne diseases into regions such as the ...

Abstract Background Radiation-induced sarcoma (RIS) is a rare, fatal late complication of radiotherapy for nasopharyngeal carcinoma (NPC), particularly in the anatomically complex skull base region. Despite the high radi...

Abstract Background Suicide attempts constitute a significant public health emergency, with Emergency Departments (EDs) serving as a primary point of contact for individuals in acute psychiatric crisis. This observationa...

Abstract Introduction Quantitative bias analysis (QBA) methods have been developed, with growing applications to epidemiological studies. Bayesian QBA (BQBA) methods may be superior in effectively using evidence-based pr...

Abstract Background Hyperglycemia, a hallmark of diabetes mellitus, is a metabolic condition that highly affects the nervous system. While evidence from epidemiological and animal studies links diabetes to dopaminergic d...

Abstract Background Epidemiological associations between multiple metals exposure and hypertension or blood pressure remain limited and inconclusive, especially for essential metals. This investigation intended to examin...

Abstract Background Chronic obstructive pulmonary disease (COPD) is a major global health burden, with emerging evidence implicating gut microbiota dysbiosis via the gut-lung axis. The Dietary Index for Gut Microbiota (D...

Abstract Background Epidemiological data consistently associate low vitamin D status with elevated cardiovascular risk, yet causal mechanisms remain contested. Methods This review synthesized evidence through a protocol-...