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Abstract Background Ferns, comprising epiphytic, aquatic, and terrestrial varieties, are good models to investigate plant terrestrialization. Vascular tissue represents a significant development in the terrestrial adapta...

Abstract Background Elite female basketball players experience a high incidence of lower-limb injuries, yet evidence remains limited regarding the applicability of common functional performance tests in this population. ...

Abstract Background Soil salinization severely restricts the growth and forage yield of Medicago sativa (alfalfa), a globally critical leguminous forage crop, yet the regulatory mechanisms governing its salt tolerance re...

Abstract Psammochloa villosa is a perennial herbaceous plant belonging to tribe Stipeae (Poaceae). It is mainly distributed in the arid and sandy Inner Mongolia Plateau and adjacent areas, demonstrating remarkable resili...

Abstract Background Zanthoxylum armatum is a vital economic crop in China, but its cultivation is challenged by abiotic stresses like drought and cold. Mitogen-activated protein kinase kinases (MAPKKs) are central signal...

Abstract Background Outcomes after curative-intent sarcoma surgery vary substantially and are incompletely explained by tumor-centered factors alone. Although CT-based body composition metrics provide objective host-rela...

Abstract Background Frailty is a known predictor of adverse surgical outcomes, yet its influence on functional recovery trajectories in South Asian settings remains underexplored. This study evaluated the association bet...

Abstract Background Subjective cognitive decline and mild cognitive impairment represent critical windows for intervention as early stages of dementia progression. Although digital health interventions have shown potenti...

Abstract Background/objectives Cardiovascular diseases (CVDs), particularly myocardial infarction (MI) and heart failure (HF), remain global causes of morbidity and mortality, despite the current treatment options. Stem ...

Abstract Background Usually Multiple Amino acids Move In and Out Transporters (UMAMITs), belonging to the MtN21/EamA-like/UMAMIT superfamily, play vital roles in amino acid transport, nodule formation, and nitrogen fixat...

Abstract Background I Kappa B Kinase Interacting Protein (IKBIP) has been reported to promote tumor progression in diverse cancers. however, the role of IKBIP in hepatocellular carcinoma (HCC) has remained unclear. Metho...

Abstract Background The complex relationship between the gut microbiome and immune system development during infancy is considered a key factor in the rising rates of pediatric allergic diseases. Food protein-induced all...

Abstract Medicinal leeches are rich in various antithrombotic components, holding significant pharmaceutical value. To investigate the differences in potential antithrombotic capacity among species, this study utilized t...

Abstract Objectives To explore the efficacy and potential neurophysiological mechanisms of 77.5 Hz transcranial alternating current stimulation (tACS) in the treatment of female adolescent non-suicidal self-injury (NSSI...

Abstract Background Understanding the association between birds, zoonotic infections, and urban environments is increasingly important due to industrialization and emerging zoonoses. Investigating the diversity, structur...

Abstract Objective This study aimed to systematically identify and validate KIF15 as a potential diagnostic and prognostic biomarker in colon cancer (CC) using integrated bioinformatics analyses. We further explored its ...

Abstract Background Dyspnea is one of the most common symptoms in the post-acute phase of COVID-19 pneumonia. Conventional pulmonary function tests and computed tomography (CT) scores often fail to show correlation with ...

Abstract Background Bacillus thuringiensis is widely employed for biological control. It can effectively suppress populations of various mosquito species, including Aedes aegypti. However, the precise mechanism underlyin...

Abstract The systematic exploration of novel bioactive compounds with superior functional properties is critical for driving innovations in agriculture, healthcare, and related fields, thereby becoming essential for adva...

Abstract The nutritional changes of giant pandas (Ailuropoda melanoleuca) in response to the seasonal variations from bamboo shoots (rich in proteins) to fibrous leaves trigger significant alterations in the structure an...

Abstract Background Prostate cancer (PCa) is a common malignant tumor in men, with a high incidence rate, posing a serious threat to human health and quality of life. Neddylation is a major post-translation modification,...