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Abstract Introduction Self-harm and suicide among young people are major public health concerns and delivering prevention and postvention support is crucial. Educational and youth organisations play a vital role in both ...

Abstract Background Postherpetic neuralgia (PHN) is a neuropathic pain syndrome that can be resistant to traditional therapies and severely impairs quality of life. The serratus posterior superior intercostal plane block...

Abstract Background The benefit of ultrasound (US) guidance for arterial blood gas sampling has not been shown in non-preselected emergency department patients; however, it has been shown to be useful in difficult cases....

Abstract Background The internal jugular vein (IJV) cannulation in the decubitus position is required in some urgent and special clinical situations, increasing the difficulty of performance. Although ultrasound guidance...

Abstract Background Adaptive designs (ADs) are increasingly used, whereby outcome data accumulated during the trial may inform a trial’s course in accordance with pre-specified rules at interim analyses. The benefits h...