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Abstract Background Cancer immunotherapy has revolutionized the clinical management of cancer due to its promising survival benefits. Although FDA-approved cancer immunotherapy primarily leverages adaptive immunity for t...

Abstract Background Fetal hypoxia is a leading cause of neonatal morbidity and mortality. Cardiotocography (CTG) is widely used to predict fetal hypoxia during labor, but its interpretation remains suboptimal. Artificial...

Abstract Background College students are a key population for opioid use, misuse, and subsequent exposure to overdose events. However, their knowledge and attitudes in response to opioid overdose warrant further study. T...

Abstract The progressive erosion of Traditional Ecological Knowledge (TEK) in Java, a process exacerbated by colonial disruption, has created a critical disjuncture in biodiversity data. This research examined the 19th-c...

Abstract Background A rapidly rising prevalence of hypertension (HTN) is observed in low-and-middle-income countries but few studies explore factors such as attitudes and beliefs, experiences and social and cultural cond...

Abstract Background Reliable identification of protein‑protein interactions (PPIs) is crucial for deciphering cellular functional networks. Current research models still face limitations in aligning heterogeneous featu...

Abstract Objective This study aims to evaluate student acceptance of a Smart Learning Platform (SLP) (based on the Chaoxing Learning System™) to deliver a cardiopulmonary physiotherapy curriculum. The SLP leverages AI-...

Abstract The Internet plays a pivotal role in tackling global climate challenges, particularly in facilitating a transition toward low-carbon behavior. However, the mechanisms by which the Internet shapes low-carbon beha...

Abstract Background Accurate and timely estimation of nitrogen nutrition index (NNI) is critical for assessing crop nitrogen (N) status and implementing precision N management. While machine learning (ML) techniques comb...

Abstract Background A core tenet of implementation science is early planning for implementation with invested partners. For health systems, aligning workflows and strategies to the local context and ensuring that the int...

Abstract Background Improving equitable access to fresh fruit and vegetables (FV) remains a critical public health priority in the UK, particularly in low-income communities where affordability, accessibility, and social...

Abstract Efficient operating room (OR) time management is critical for healthcare quality, yet the precise relationships among key OR metrics remain underexplored. This study analyzed data from 3,423 patients treated in ...

Abstract Background Preterm low birth weight (PLBW) is a major global contributor to neonatal morbidity and mortality. This study aims to develop and evaluate a novel artificial neural network (ANN) based predictive mode...

Abstract The development of Artificial Intelligence (AI) is rapidly advancing, and AI tools are being integrated into many aspects of daily life, including medical care and public health. The full extent to which AI rela...

Abstract Background Alcohol use disorder (AUD) represents a tremendous societal burden, yet few efficacious therapies are available and widely used. Pre-clinical and human observational data support fibroblast growth fac...

Abstract Background Tobacco cessation markedly improves cancer treatment outcomes. As part of the National Cancer Institute (NCI) Cancer Moonshot, the Cancer Center Cessation Initiative (C3I) funded 52 U.S. National Canc...

Abstract The “Broadband China” strategy has enhanced digital infrastructure through urban fiber upgrades, rural broadband expansion, and improved network performance. This research employs the multi-period difference...

Abstract Background Diabetes is a leading cause of mortality globally and ranks as the eighth leading cause of death in the United States. Affecting approximately 8.9% of Americans, diabetes imposes a substantial public ...