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15 resultados encontrados.

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Association of serum uric acid and serum uric acid/creatinine ratio with metabolic dysfunction-associated fatty liver disease in young adults: a retrospective study
Artículo
Acceso abierto Artículo DOAJ
Association of serum uric acid and serum uric acid/creatinine ratio with metabolic dysfunction-associated fatty liver disease in young adults: a retrospective study
Yue Li et al · BMC · 2026 · ISSN 1472-6823
Abstract Background Metabolic dysfunction-associatedsteatotic liver disease (MASLD) has become the most prevalent chronic liver disease worldwide. Its incidence continues to rise with a marked trend toward younger age gr...
LCC LCC:Diseases of the endocrine glands. Clinical endocrinologyIdioma eng
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Bidirectional association between non-steatotic chronic liver disease and heart disease: the potential link of insulin resistance
Artículo
Material complementario disponible Artículo DOAJ
Bidirectional association between non-steatotic chronic liver disease and heart disease: the potential link of insulin resistance
Yan Zhang et al · BMC · 2026 · ISSN 1475-2840
Abstract Background Chronic liver disease (CLD) and heart disease (HD) are major contributors to global morbidity and mortality. Although increasing evidence supports close interactions between the liver and heart, popul...
LCC TENDOkRpc2Vhc2VzIG9mIHRoZSBjaXJjdWxhdG9yeSAoQ2FyZGlvdmFzY3VsYXIpIHN5c3RlbQ~~Idioma eng
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Extracellular vesicles derived from live or apoptotic mesenchymal stem cells: comparison of the effects of two extracellular vesicles on liver fibrosis
Artículo
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Extracellular vesicles derived from live or apoptotic mesenchymal stem cells: comparison of the effects of two extracellular vesicles on liver fibrosis
Ruobing Ju et al · BMC · 2026 · ISSN 1471-230X
Abstract Background Mesenchymal stem cells (MSCs) have become a promising treatment of liver fibrosis which is a key process in liver diseases. Recent studies have shown that transplanted MSCs undergo rapid apoptosis and...
LCC LCC:Diseases of the digestive system. GastroenterologyIdioma eng
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Fine-tuned lightweight language models for structured extraction of liver cancer imaging free-text report: a comparative analysis with existing large language models
Artículo
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Fine-tuned lightweight language models for structured extraction of liver cancer imaging free-text report: a comparative analysis with existing large language models
Yang-Di Luo et al · BMC · 2026 · ISSN 1471-2342
Abstract Background Organizing free-text patient data into a structured format is labor-intensive and time-consuming. This study aims to evaluate the effectiveness of a fine-tuned lightweight language model in structurin...
LCC TENDOk1lZGljYWwgdGVjaG5vbG9neQ~~Idioma eng
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Nanoscaffold-based 3D human liver spheroids for predictive hepatotoxicity screening of antimalarial compounds from the global health priority box
Artículo
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Nanoscaffold-based 3D human liver spheroids for predictive hepatotoxicity screening of antimalarial compounds from the global health priority box
Lina Wu et al · BMC · 2026 · ISSN 1756-3305
Abstract Background Drug-induced liver injury (DILI) remains a significant barrier to the safe and efficient use of antimalarial medicines. Many promising compounds fail in late-stage development or post-marketing owing ...
LCC TENDOkluZmVjdGlvdXMgYW5kIHBhcmFzaXRpYyBkaXNlYXNlcw~~Idioma eng
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Preclinical efficacy and safety evaluation of human embryonic stem cell-derived functional hepatocytes for a clinical trial in acute liver failure
Artículo
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Preclinical efficacy and safety evaluation of human embryonic stem cell-derived functional hepatocytes for a clinical trial in acute liver failure
Yi Sun et al · BMC · 2026 · ISSN 1757-6512
Abstract Background Acute liver failure (ALF) is a life-threatening syndrome characterized by rapid deterioration of liver function, resulting in high mortality and posing a substantial global health burden. Human embryo...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~; TENDOkJpb2NoZW1pc3RyeQ~~Idioma eng
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Prevalence of liver disorders in children and adolescents with type 1 diabetes mellitus
Artículo
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Prevalence of liver disorders in children and adolescents with type 1 diabetes mellitus
Mirna Natalija Anicic et al · BMC · 2025 · ISSN 1471-2431
Abstract Background Children and adolescents with type 1 diabetes mellitus (T1DM) occasionally develop liver disorders. Glycogenic hepatopathy and non-alcoholic fatty liver disease are the most common conditions found in...
LCC TENDOlBlZGlhdHJpY3M~Idioma eng
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Semi-automated isolation of parenchymal and non-parenchymal liver cells from mice and humans with enhanced stellate cell fraction
Artículo
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Semi-automated isolation of parenchymal and non-parenchymal liver cells from mice and humans with enhanced stellate cell fraction
Anne Dropmann et al · BMC · 2026 · ISSN 2045-3701
Abstract Background & aims Understanding of the dynamic changes of hepatocytes, hepatic stellate cells (HSC), Kupffer cells (KC), and liver sinusoidal endothelial cells (LSEC) is critical for studying liver (patho)physio...
LCC TENDOkJpb3RlY2hub2xvZ3k~; LCC:Biology (General); TENDOkJpb2NoZW1pc3RyeQ~~Idioma eng
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The diagnostic value of ultrasound viscoelastic imaging for biliary and vascular complications after liver transplantation: a single-center retrospective study
Artículo
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The diagnostic value of ultrasound viscoelastic imaging for biliary and vascular complications after liver transplantation: a single-center retrospective study
Minghui Tai et al · BMC · 2026 · ISSN 1471-230X
Abstract Background Postoperative biliary and vascular complications (including stenosis, thrombosis, and occlusion) after liver transplantation (LT) can impair graft function, increase reoperation needs, and elevate pat...
LCC LCC:Diseases of the digestive system. GastroenterologyIdioma eng
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Incidence and risk factors for incisional hernia after partial liver resection via an inverted L-incision: a retrospective single-centre cohort study
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Incidence and risk factors for incisional hernia after partial liver resection via an inverted L-incision: a retrospective single-centre cohort study
Banseok Kim et al · BMC · 2026 · ISSN 1471-2482
Abstract Background Incisional hernias are a relevant complication after abdominal surgery, but data on their occurrence after open liver resection, particularly via inverted L-incision, are limited. Methods We conducted...
LCC TENDOlN1cmdlcnk~Idioma eng
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Synergistic regulation of selenium yeast and vitamin E on the rumen microbiota-VFA-liver axis in lambs
Artículo
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Synergistic regulation of selenium yeast and vitamin E on the rumen microbiota-VFA-liver axis in lambs
Shangwu Ma et al · BMC · 2026 · ISSN 1471-2180
Abstract Background In intensive livestock production, various environmental and management stressors often compromise the oxidative and immune homeostasis of lambs, thereby impairing their growth performance and health....
LCC TENDOk1pY3JvYmlvbG9neQ~~Idioma eng
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Global and regional prevalence, burden, and risk factors for MASLD in children and adolescents aged 5 to 24 years: a systematic review, meta-analysis, and modeling study
Artículo
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Global and regional prevalence, burden, and risk factors for MASLD in children and adolescents aged 5 to 24 years: a systematic review, meta-analysis, and modeling study
Yunfei Liu et al · BMC · 2026 · ISSN 1741-7015
Abstract Background Obesity is associated with metabolic dysfunction-associated steatotic liver disease (MASLD). Despite the rising prevalence of obesity among children and adolescents, no studies have examined risk fact...
LCC LCC:MedicineIdioma eng
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OneSTOP (One-Stop Telehealth Obesity Program): study protocol for an open-label randomized controlled trial on the use of telecare and digital platforms for multidisciplinary management of weight management and related comorbidities
Artículo
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OneSTOP (One-Stop Telehealth Obesity Program): study protocol for an open-label randomized controlled trial on the use of telecare and digital platforms for multidisciplinary management of weight management and related comorbidities
Joan Khoo et al · BMC · 2026 · ISSN 1745-6215
Abstract Background Obesity is prevalent in Singapore and is a driver of multiple co-morbidities including type 2 diabetes, metabolic dysfunction associated steatotic liver disease (MASLD), and cardiovascular disease. Tr...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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Robust human genetic evidence supporting causal effects of FGF21 on reducing alcohol consuming behaviours
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Robust human genetic evidence supporting causal effects of FGF21 on reducing alcohol consuming behaviours
Héléne T. Cronjé et al · BMC · 2026 · ISSN 1741-7015
Abstract Background Alcohol use disorder (AUD) represents a tremendous societal burden, yet few efficacious therapies are available and widely used. Pre-clinical and human observational data support fibroblast growth fac...
LCC LCC:MedicineIdioma eng
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β-Hydroxybutyrate upregulates hepatic histone β-hydroxybutyrylation modification, promotes the expression of PPARα, and alleviates the hepatic steatosis in MASLD
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β-Hydroxybutyrate upregulates hepatic histone β-hydroxybutyrylation modification, promotes the expression of PPARα, and alleviates the hepatic steatosis in MASLD
Dongze Li et al · BMC · 2026 · ISSN 1868-7083
Abstract Background Metabolic dysfunction-associated steatotic liver disease (MASLD) stands as the most widespread chronic liver disorder globally. Histone β-hydroxybutyrylation (Kbhb)—a novel post-translational modif...
LCC LCC:Medicine; LCC:GeneticsIdioma eng
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