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Abstract Background The exponential rise in colorectal cancer surgeries among older adults combined with 30-day readmission rates as high as 25% highlights the crucial need to optimize post-discharge care. While geriatri...

Abstract Background Optimization of biotechnological processes is traditionally limited by time-consuming trial-and-error approaches and the complexity of simultaneously optimizing multiple, often conflicting objectives....

Abstract Statement of problem Immediate dentin sealing (IDS) is used to improve bonding of indirect restoration. However, interaction between polyether impressions may affect the future bonding of indirect restoration. S...

Abstract Objective Current diagnostic paradigms for Crohn’s disease (CD) activity assessment remain fragmented across imaging and laboratory modalities. This study seeks to investigate the diagnostic efficacy of intest...

Abstract Generative artificial intelligence is reshaping how researchers discover protein-binding compounds and develop them into drug candidates. Unlike traditional methods that screen existing molecules, structure-base...

Abstract Background Protein-protein interaction (PPI) network-based protein function prediction algorithms, which use the guilt-by-association principle, are widely applied in medical and human domains, but they are comp...

Abstract Background High-throughput sequencing (HTS) enables the detection of low-frequency HIV-1 drug resistance mutations (DRMs) that are often missed by conventional Sanger sequencing. However, the clinical implementa...