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Abstract Background Children with congenital and acquired heart disease (CAHD) are at high risk for venous thromboembolism (VTE). Traditional anticoagulants such as vitamin K antagonists (VKAs) and low-molecular-weight h...

Abstract Background The growing global aging population and the high prevalence of oral diseases among the elderly significantly affect their quality of life. This study aimed to assess the current status of oral health ...

Abstract Background Identification of disease-associated spectral alterations of oral squamous cell carcinoma (OSCC) and oral potentially malignant disorders (OPMD) is critical to improving patient outcomes. Protein stru...

Abstract The multifaceted pathogenesis and multi-cellular involvement of diabetic nephropathy (DN) stand in stark contrast to the inadequacy of conventional single-target therapeutic strategies. This disparity underscore...

Abstract Background Sjögren’s disease is a systemic autoimmune disease characterized by dysfunction of the salivary and lacrimal glands, leading to xerostomia and xerophthalmia. Case presentation A 55-year-old Hispani...

Abstract Periodontitis and dental caries are the most widespread non-communicable oral disorders worldwide, affecting approximately 3.5 billion people worldwide. Nevertheless, existing in vitro models do not accurately ...

Abstract Introduction Gestational diabetes mellitus (GDM) is closely related to insulin resistance (IR) and is usually diagnosed in mid-pregnancy, limiting opportunities for early risk identification. We evaluated six si...

Abstract Background Alzheimer’s disease (AD) is a growing global health concern, and emerging evidence suggests that oral health—particularly tooth loss—may be linked to cognitive decline. While implant therapy eff...

Abstract Background Despite the expansion of antiretroviral treatment programmes, the incidence and mortality of HIV-associated cryptococcal meningitis remain high in Africa. Cryptococcal antigen (CrAg) in the blood prec...