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Abstract Introduction Quantitative bias analysis (QBA) methods have been developed, with growing applications to epidemiological studies. Bayesian QBA (BQBA) methods may be superior in effectively using evidence-based pr...

Abstract Background Our research team has used the highly cited Consolidated Framework for Implementation Research (CFIR) a priori throughout the research process to better understand influences on implementation outcome...

Abstract Background Programmed death-ligand 1 (PD-L1) is widely used as a predictive biomarker for response to immune checkpoint inhibitors in gastric cancer (GC); however, its independent prognostic value for overall su...

Abstract Background Children with Unilateral Cerebral Palsy (UCP) are characterized by significant upper limbs (ULs) impairment that hinders daily activities and participation, requiring accurate assessment. Although mot...

Abstract Background Most climate and health studies are based on a single extreme weather event and do not consider multiple physical processes across spatial and temporal scales. Our aim was to explore the current lands...

Abstract Background The holistic health of children, encompassing physical, psychological, and social domains, plays a crucial role in long-term societal development. However, evidence suggests that many young people eng...

Abstract Background Sub-Saharan Africa (SSA) has been witnessing a persistent increase in the burden of cardiovascular diseases (CVD), such as stroke and heart disease, over several decades. A key driver of this burden h...

Abstract Background Subjective cognitive decline and mild cognitive impairment represent critical windows for intervention as early stages of dementia progression. Although digital health interventions have shown potenti...

Abstract Background There have been emerging clinical trials investigating the efficacy of synthetic-graft-augmented autografts in anterior cruciate ligament reconstruction (ACLR) in recent years. Hamstring tendon and Li...

Abstract Background Vascular calcification is a major pathological process driving cardiovascular morbidity and mortality, yet effective therapies are lacking. This study aims to identify novel causal plasma proteins and...

Abstract Background Deaths from suicide, drug overdose, and alcohol-specific causes, collectively termed “deaths of despair” (DoD), represent a growing public health concern. Quantitative research has linked these de...

Abstract Background Maternal and perinatal quality collaboratives (M/PQCs) across nearly all U.S. states focus on improving health care and outcomes for birth parents and their infants. In the context of increases in mat...

Abstract Background This is the first systematic review and meta-analysis aimed at assessing the current status of robotic-assisted implant surgery (r-CAIS) in zygomatic implant (ZI) placement, with a particular focus on...

Abstract Background Microglial activation is increasingly recognized as a critical contributor to both the initiation and chronification of migraine. Recent advances have highlighted the importance of receptor-mediated s...

Abstract Background Digital teaching methods are established for imparting theoretical knowledge in the training of health professions. While digital formats are increasingly used in education, evidence on their capacity...

Abstract Background Lung cancer stigma (i.e., perceived and internalized negative appraisal and devaluation associated with lung cancer) is a clinically significant psychosocial concern among individuals diagnosed with l...