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Abstract Background Tuberculosis remains a major public health challenge in Somalia, where a fragile health system and reliance on private providers complicate care. Although Public-Private Partnerships are globally reco...

Abstract Objective Eating disorders (ED) are most prevalent in women of reproductive age. EDs affect fertility, maternal BMI, and obstetric outcomes. During the early postpartum period, women with an ED history are at hi...

Abstract Multifocal Ectopic Purkinje-related Premature Contractions (MEPPC) syndrome is a recently recognized rare channelopathy caused by gain-of-function mutations in the SCN5A gene, leading to a high burden of prematu...

Abstract While binge drinking can significantly impact health negatively, it has become increasingly important to understand how sex differences contribute to this hazardous behavior, which may also serve as a risk facto...

Abstract Background Multi-Family Therapy for Anorexia Nervosa (MFT-AN) unites families navigating similar difficulties to promote more rapid recovery for adolescents with eating disorders. Designed as a collaborative, gr...

Abstract Background Nipple discharge is one of the most common breast complaints, reported by 80% of women outside the breastfeeding period. It may result from physiological or pathological causes, including intraductal ...

Abstract Background Surgeons work in high-pressure, high-risk environments, which can lead to physical and mental health challenges. Physical activity (PA) has known benefits for health, stress reduction, and professiona...

Abstract Objective Given anorexia nervosa’s (AN) status as one of the most difficult psychiatric disorders to treat, with the highest mortality rate, with millions of dollars spent on researching its treatment, and dec...

Abstract Background Electronic cigarette consumption has increased worldwide. In Latin America, multiple gaps exist regarding health policies on manufacturing and restriction of electronic cigarette use. Although previou...

Abstract Background The primary objective of this study is to identify independent risk factors associated with secondary pulmonary hypertension (PH) in silicosis patients through retrospective statistical analysis and t...

Abstract Background High-fidelity simulation is a cornerstone of emergency medicine (EM) education and is used by a majority of EM clerkships. Traditional high-fidelity simulation involves learners working through a pred...

Abstract Parasitic diseases such as malaria, leishmaniasis, and schistosomiasis remain difficult to treat due to the pathogens’ complex life cycles, intracellular niches, and resistance to conventional therapies. Tradi...

Abstract This meta-analysis reveals a significant association between Body Mass Index (BMI) and the risk of osteoporosis. Being underweight may increase the risk of osteoporosis, while being overweight or obese may reduc...

Abstract Objective Medical education aims to prepare future physicians for high-quality patient care. This prospective study examines the perceptions of medical students and clinical teachers with regard to teaching in o...

Abstract Background/Objectives Dilated cardiomyopathy (DCM) is characterized by heart failure and cardiac dilation, distinguishing it from ischemic and non-ischemic heart diseases. To date, more than 50 genes have been i...

Abstract Background Endoscopic vidian neurectomy has been performed for decades on patients with refractory allergic rhinitis and vasomotor rhinitis. Although the surgical approach has evolved continuously, it still has ...

Abstract Background Sphincter preservation (SP) during laparoscopic total mesorectal excision (LaTME) for low rectal cancer is challenged by a deep, narrow pelvis. Robust, MRI-based predictors for both SP success and ope...

Abstract Background Disordered eating behaviors are prevalent among children and adolescents with overweight and obesity but are frequently overlooked or underrecognized. We performed a scoping review to identify and map...

Abstract The core pathological mechanisms of diabetic microvascular diseases, such as nephropathy, diabetic retinopathy (DR), and neuropathy, involve the dysfunction and loss of microvascular endothelial cells (ECs), vas...

Abstract Automobile cabin air filter-deposited particulate matter represents an underappreciated exposure source, yet the differential toxicity between filter sides and underlying mechanisms remain unclear. Here, we syst...

Abstract Background The genetic architecture of circulating amino acids (AAs) and microbiota-related metabolites (MRMs) in relation to cardiometabolic disease remains poorly characterized in East Asian populations, limit...

Abstract Background The timing of puberty in offspring is influenced by various factors, including genetics and environment. While some studies suggest a link between parental age at childbirth and pubertal timing, the e...

Abstract Objective To investigate the association between the Systemic Immune-Inflammation Index (SII), Systemic Inflammation Response Index (SIRI), and in-stent restenosis (ISR) following percutaneous coronary intervent...

Abstract Objectives DNA methylation (DNAm) can change dynamically in response to intrinsic or external exposures. Characteristic methylation profiles are associated with accelerated biological ageing and poorer health ou...