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Abstract Background Diabetic Foot Ulcers (DFUs) represent a global healthcare challenge, imposing substantial socioeconomic burdens due to their increasing incidence and associated mortality. This study evaluates the eff...

Abstract Food safety is a critical public health and economic issue in Afghanistan, where regulatory frameworks are evolving in response to complex political, social, and infrastructural challenges. This study examines t...

Abstract Background Safe anesthesia is fundamental to safe surgery and depends on facility readiness, team behaviors, and consistent adherence to safety standards such as the World Health Organization (WHO) Surgical Safe...

Abstract Background This systematic review and meta-analysis evaluates the safety and efficacy of emerging prostate-specific membrane antigen (PSMA) radioligand therapy (RLT) agents used beyond [¹⁷⁷Lu]Lu-PSMA in met...

Abstract Background Neuraxial block failure in obese parturients is a significant clinical challenge, leading to inadequate pain relief and increased maternal risk. Novel techniques such as the Combined Spinal-Epidural (...

Abstract Background Acute liver failure (ALF) is a life-threatening syndrome characterized by rapid deterioration of liver function, resulting in high mortality and posing a substantial global health burden. Human embryo...

Abstract Background Migraine burden is over twice as high among females than males. Although sex differences are recognized in migraine, robust sex-specific guidance for management remains limited. Objective To systemati...

Abstract Background The IDH-mutant low-grade glioma (LGG) involving corpus callosum (ccLGG) is a rare type of LGG which has a poorer prognosis. To evaluate the efficacy of multimodal techniques (comprising neuronavigatio...

Abstract Background Ankylosing spondylitis (AS) is a chronic inflammatory disorder marked by spinal ossification that leads to progressive thoracolumbar kyphosis (TLK). We previously introduced vertebral body compression...

Abstract Background Anti-amyloid monoclonal antibodies are entering clinical practice for early symptomatic Alzheimer’s disease (AD), but European real-world data on feasibility, safety, and biomarker monitoring remain...

Abstract Background The arthroscopic posterior transseptal approach (TSA) allows improved visualization of the posterior compartment of the knee joint. However, it can be associated with increased risks particularly rega...