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Abstract Background Diarrhoeal diseases remain a major global health concern, particularly in low- and middle-income countries, contributing significantly to morbidity and mortality among children under five. This study ...

Abstract Background Klebsiella pneumoniae complex (Kp) is a relevant neonatal pathogen colonizing preterm infants. While outbreak investigations often focus on multidrug-resistant strains, the epidemiology and genomic dy...

Abstract Background Around a third of suicides in the United Kingdom occur in public spaces, such as on the railways, at bridges, or coastal locations. Increasingly, the use of Artificial Intelligence and other smart tec...

Abstract Background Tuberculosis (TB) remains a critical global public health issue, particularly in rapidly urbanizing regions where population density and migration facilitate transmission. While whole-genome sequencin...

Abstract Background Anthropogenic pressures, including urbanisation, globalisation and climate change, have facilitated an increased risk for emergence or re-emergence of mosquito-borne diseases into regions such as the ...

Abstract Dysregulated expression of tumor suppressor genes can impair their functions, even promoting oncogenesis. Expression of p53β mRNA can be regulated by alternative splicing and RNA surveillance, otherwise transla...

Abstract Background Malaria continues to be the foremost deadly disease and a cause of substantial economic deficit in Ethiopia. Data from malaria monitoring programs can be used to assess prevalence and trends of the di...

Abstract Background Rodents are reservoirs of zoonotic viruses that significantly threaten public health. This study investigated the RNA virome of 624 rodents collected across six ecological zones in Yunnan Province, Ch...

Abstract The VII Brazilian Symposium on Toxoplasmosis (SIMBRATOX) and the IV International Symposium on Toxoplasmosis (SINTOX) were held remotely from October 6 to 8, 2025, under the theme “Toxoplasmosis – Strengthen...

Abstract Background The global expansion of Aedes aegypti and Aedes albopictus mosquitoes has intensified arboviral epidemics, generating annual socio-economic losses exceeding 2 billion US dollars, mainly in the America...

Abstract Background In Libreville, Gabon, the Melen sentinel site has monitored malaria among febrile children for over a decade, offering a lens on intra-urban transmission. We aimed to characterize neighborhood-level s...

Abstract In response to the emerging threat of insecticide resistance in malaria vectors, insecticides are being repurposed for vector control or developed de novo. The longevity of disease control programs will require ...

Abstract Background Hereditary breast and ovarian cancer (HBOC) confers a markedly increased lifetime risk of breast and ovarian cancers. As no effective surveillance method for early detection of ovarian cancer has been...

Abstract Purpose Patients with nasopharyngeal carcinoma (NPC) exhibiting persistent EBV DNA positivity throughout treatment (a “D-D-D” trajectory) represent a high-risk group with undefined management strategies. Thi...

Abstract Background Pestiviruses such as bovine viral diarrhea virus (BVDV) or the ovine border disease virus (BDV) are not strictly species-specific and can be transmitted between related animal species. Due to serologi...

Abstract Background Diabetes mellitus is a major public health concern in low- and middle-income countries, particularly in fragile health systems such as Afghanistan. Limited community-based evidence exists on the burde...

Abstract Background The role of leukocyte telomere length (LTL) in predicting lung cancer risk remains controversial, particularly in individuals with pulmonary nodules. Methods We conducted a prospective cohort study of...

Abstract Background Understanding how the respiratory microbiota matures with age is key to improving poultry health and pathogen surveillance, yet the ecological processes shaping this transition remain elusive. We aime...

Abstract Background Shigella species are a significant global public health threat with the highest burden of Shigella-associated diarrhoea in children under five years of age, particularly in low- and middle-income coun...

Abstract Background Invasive candidiasis (IC) remains a major cause of morbidity and mortality worldwide, particularly among critically ill and immunocompromised patients. The emergence of antifungal resistance, especial...