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Repertoires of Autophagy in the Pathogenesis of Ocular Diseases

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Repertoires of Autophagy in the Pathogenesis of Ocular Diseases

Yujie Li; Qin Jiang; Guo-Fan Cao; Jin Yao; Biao Yan · Cellular Physiology and Biochemistry · 2015

Autophagy is an important intracellular degradative process that delivers cytoplasmic proteins to lysosome for degradation. Dysfunction of autophagy is implicated in several human diseases, such as neurodegenerative dise...

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Heat Shock Protein A12B Protects Vascular Endothelial Cells Against Sepsis-Induced Acute Lung Injury in Mice

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Heat Shock Protein A12B Protects Vascular Endothelial Cells Against Sepsis-Induced Acute Lung Injury in Mice

Yi Chen; Lei Wang; Qiuxiang Kang; Xu Zhang; Guifang Yu; Xiaojian Wan; Jiafeng Wang; Keming Zhu · Cellular Physiology and Biochemistry · 2017

BACKGROUND: Pulmonary endothelial injury is a critical process in the pathogenesis of acute lung injury (ALI) during sepsis. Heat shock protein A12B (HSPA12B) is mainly expressed in endothelial cells and protects against...

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