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ABSTRACT: Introduction: Nasopharyngeal carcinoma (NPC) is endemic in Asians and North Africans. Radiologically it is first identified as asymmetry of the Fossa of Rosenmüller (FR) in the nasopharynx, which is also visi...

ABSTRACT: Introduction and aims: To provide the research progress on the cGAS-STING signalling pathway and its related roles in various oral diseases. Methods: We reviewed the recent research on cGAS-STING in PubMed. Th...

Introduction and Aims: Mandibular movement is a complex physiological process essential for orofacial function. Patients with disc displacement without reduction (DDWoR) exhibit significant kinematic impairments, which a...

Introduction and aims: Submucous cleft palate (SMCP) is a congenital craniofacial malformation. While TBX22 is a known pathogenic gene, the potential role of TBX15 in SMCP remains unclear. This study aimed to investigate...

Introduction: Computer-aided design and computer-aided manufacturing (CAD/CAM) have transformed modern dentistry, yet evidence from the Caribbean remains limited. Objective: To assess CAD/CAM adoption among dentists in t...

The characteristic oral environment – with its dynamic clearance, moisture, microbial load, and inflammatory potential – makes oral diseases highly prevalent and therapeutically challenging. Metal-organic frameworks ...

Introduction: The advancement of AI-assisted oral disease diagnosis critically relies on the availability of annotated, high-quality datasets and resilient deep learning architectures. Nevertheless, progress in this doma...

Objectives: Survival rates in patients with oral squamous cell carcinoma (OSCC) have failed to improve greatly over time, and novel biomarkers are urgently needed. Therefore, the aim was to evaluate the predictive abilit...

Objectives: This study utilized dual control groups, caries patients (a representative bacterial infectious disease) and healthy individuals, to identify the core microbiome specific to dental fluorosis and elucidate the...

Objectives: To analyse the relationship between oral frailty (OF) and cognitive impairment in older adults and explore the association between OF and different domains of cognitive function. Methods: A total of 461 commu...

This study aimed to evaluate the performance of deep learning models for segmenting the augmented bone following transalveolar sinus floor elevation (TSFE). Cone-beam computed tomography (CBCT) data from 103 patients und...

Objectives: Deep learning networks have achieved significant progress in caries diagnosis, but automated localization and numbering of carious teeth in cone-beam computed tomography (CBCT) images remain underexplored. Th...

Background: Conventional glass ionomer cement (GIC) is widely used as a restorative base and liner owing to its chemical adhesion to dentine, fluoride release, and favourable biocompatibility. Nevertheless, its intrinsic...

ABSTRACT: Background: Lip and oral cavity cancer (LOCC) remains a significant issue in Europe, with an uneven public health burden. While trends have shifted, regional and sex-specific disparities persist due to modifia...

Objectives: To investigate the relationship between caries in primary teeth and caries in permanent teeth among primary school students, and to identify potential effect modifiers of this relationship. Methods: This retr...

ABSTRACT: Introduction and aims: Oral squamous cell carcinoma (OSCC) is a common malignant tumour of the head and neck region. In recent years, the relationship between pyroptosis and tumours has received increasing att...

Background: Oral squamous cell carcinoma (OSCC) is a common oral cavity malignancy with a poor prognosis. Although chemokine-like receptor 1 (CMKLR1) has been implicated in tumor progression in several types of cancer, i...

ABSTRACT: Objectives: To evaluate and synthesise the current evidence on the efficacy of laser-activated irrigation in endodontics, with a focus on microbial reduction, postoperative outcomes, and its potential as an ad...

Introduction and Aims: Ranula is a mucus retention cyst originating from the sublingual gland, and surgical intervention has traditionally been the main treatment. However, surgery is often associated with recurrence, ri...

Introduction and aims: Conventional removable partial denture (RPD) clasp fabrication with wrought wire depends on operator skill, limiting efficiency and reproducibility. This study compared robotically and manually ben...

Introduction and aims: Skeletal Class II malocclusion is heterogeneous, and conventional two-dimensional cephalometry may not fully capture relevant three-dimensional (3D) craniofacial variation. This study aimed to iden...

Introduction and aims: The aim of this study was to collect and analyze country-specific information on corporate dental chains in the European Union, with a particular focus on their prevalence, organizational structure...

Objective: The objective of this study was to synthesise a novel silver nanocomposite incorporating quorum-quenching enzyme N-acyl-homoserine lactone-lactonase Est816 (Ag-Est816) to inhibit periodontal biofilm formation....

Objective: To explore and compare the extent of maximal gingival display among four different facial expressions, including the requested smile, Duchenne smile, grimace of disgust, and funnel-shaped expression, using Aut...