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Materias / palabras clave: Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry: Neurology. Diseases of the nervous system

Materias / palabras clave: Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry

Mild cognitive impairment (MCI) and dementias, such as Alzheimer’s disease (AD)-induced dementia and vascular dementia, are major public health burdens. The blood-brain barrier (BBB) disruption, systemic inflammation, ...

Chronic psychosocial stress is a major risk factor for anxiety, depression and related disorders, yet a hypothalamic-pituitary-adrenal (HPA) axis centric framework alone is insufficient to explain stress-induced vulnerab...

Gastrointestinal (GI) diseases are common multifactorial disorders involving chronic inflammation, epithelial barrier disruption, immune dysregulation, gut microbiota imbalance, and abnormalities in motility and gut–br...

Exosomes, a specialized class of extracellular vesicles, exhibit significant therapeutic potentials for neurological disorders, in particular for vascular dementia (VaD). VaD is the second most common form of dementia, c...

Microplastics (MPs), environmental pollutants resulting from the degradation of plastic products and industrial processes, have become ubiquitous in global ecosystems. MPs can enter the human body through ingestion, inha...

The incidence of metabolic disorders including obesity, type 2 diabetes and metabolic syndrome have seriously increased in the last decades. These diseases - with growing impact in modern societies - constitute major ris...

Coenzyme A (CoA) is a vital cofactor involved in energy metabolism, lipid biosynthesis, protein modification, and epigenetic regulation. Disruptions in CoA biosynthesis have been implicated in neurometabolic disorders su...

Neurodegenerative diseases (NDs) constitute a growing global health burden driven by population aging and remain without disease-modifying therapies. Although chronic neuroinflammation and aberrant protein aggregation ar...