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Introduction and aims: Early clinical exposure (ECE) integrates students into clinical settings during theoretical learning, aiming to foster professional development. This systematic review aims to comprehensively evalu...

ABSTRACT: Objective: To investigate the effects of commonly prescribed antibiotics and nonsteroidal anti-inflammatory drugs (NSAIDs) during early life on enamel development through a systematic review with quantitative ...

ABSTRACT: Introduction and aims: To provide the research progress on the cGAS-STING signalling pathway and its related roles in various oral diseases. Methods: We reviewed the recent research on cGAS-STING in PubMed. Th...

Introduction and Aims: Mandibular movement is a complex physiological process essential for orofacial function. Patients with disc displacement without reduction (DDWoR) exhibit significant kinematic impairments, which a...

Introduction and aims: Submucous cleft palate (SMCP) is a congenital craniofacial malformation. While TBX22 is a known pathogenic gene, the potential role of TBX15 in SMCP remains unclear. This study aimed to investigate...

The characteristic oral environment – with its dynamic clearance, moisture, microbial load, and inflammatory potential – makes oral diseases highly prevalent and therapeutically challenging. Metal-organic frameworks ...

Background: This study aims to evaluate the effectiveness and efficiency of combined multiple-case teaching (MCT) and narrative medicine teaching (NMT) method compared with lecture-based learning (LBL) in the clinical pr...

Introduction: The advancement of AI-assisted oral disease diagnosis critically relies on the availability of annotated, high-quality datasets and resilient deep learning architectures. Nevertheless, progress in this doma...

Objectives: Deep learning networks have achieved significant progress in caries diagnosis, but automated localization and numbering of carious teeth in cone-beam computed tomography (CBCT) images remain underexplored. Th...

In the search for new compounds for the treatment of Chagas disease, the cysteine protease cruzipain remains as one of the most attractive biomolecular targets for drug development. Thiosemicarbazones (TSCs) have been id...

Research on lactobacilli from traditional food niches have received increasing attention for theirbeneficial properties. In this study, selected bacteriocin-producing lactobacilli strains previouslyisolated and character...

This work presents, for the frst time, the development of magnetic composites using activated biochar (BC-Act) derived from yerba mate waste. It includes an analysis of the effect of the activation process on the formati...

Introduction and aims: Increasing evidence suggests that marginal zone B and B1 cell-specific protein (MZB1) plays crucial roles in inflammatory responses, endoplasmic reticulum (ER) stress, and cell survival, but its fu...

Objectives: The concept of ‘One Health’ emphasizes the intrinsic connection of ‘Human Health’ with ‘Animal Health’ and ‘Environmental Health’. The research landscape of the intersection of one health in t...

Background: Spinal cord injury (SCI) has emerged as a major challenge to global public health due to its low recovery rate and high disability rate, making the development of novel therapeutic approaches imperative. Mese...

Introduction and aims: For decades, orthodontic diagnosis and treatment have primarily depended on physical models, imaging techniques, and three-dimensional (3D) imaging technologies. Nevertheless, single-modal data exh...

Background: Outer membrane vesicles (OMVs) from Gram-negative bacteria are spherical lipid bilayer nanostructures with diameters of 20 to 250 nm. Porphyromonas gingivalis (P. gingivalis), a keystone periodontal pathogen,...

Introduction and aims: This study aimed to collect data of national dental associations (NDAs) on workforce composition, employment patterns, academic representation, specialization, and women’s participation in leader...

Objectives: By establishing a rat model of periapical infection, this study compared the anti‑inflammatory effects of caerin 1.1/1.9 hydrogel and calcium hydroxide paste, aiming to provide a novel therapeutic strategy ...

Objectives: This study aimed to develop an automated deep learning (DL) system to detect and classify second molar (M2) pathologies associated with impacted third molars (ITMs) on panoramic radiographs. We sought to enha...

Materias / palabras clave: Oral health; Global burden of disease; Health status indicators; Health care economics; Cost-effectiveness analysis; Quality-adjusted life years

ABSTRACT: Introduction: The links between oral health and female ageing are poorly understood, but many changes occur in the oral cavity of menopausal women that affect quality of life, and few current oral health inter...

Background and Objectives: Given the increasing use of artificial intelligence (AI) tools for dental health information, this study compared patients' perceived health information literacy for AI chatbots, measured using...