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Research on lactobacilli from traditional food niches have received increasing attention for theirbeneficial properties. In this study, selected bacteriocin-producing lactobacilli strains previouslyisolated and character...

Objectives: To analyse the relationship between oral frailty (OF) and cognitive impairment in older adults and explore the association between OF and different domains of cognitive function. Methods: A total of 461 commu...

Background: Oral squamous cell carcinoma (OSCC) is a common oral cavity malignancy with a poor prognosis. Although chemokine-like receptor 1 (CMKLR1) has been implicated in tumor progression in several types of cancer, i...

Introduction and Aims: Mandibular movement is a complex physiological process essential for orofacial function. Patients with disc displacement without reduction (DDWoR) exhibit significant kinematic impairments, which a...

Introduction and aims: Submucous cleft palate (SMCP) is a congenital craniofacial malformation. While TBX22 is a known pathogenic gene, the potential role of TBX15 in SMCP remains unclear. This study aimed to investigate...

The characteristic oral environment – with its dynamic clearance, moisture, microbial load, and inflammatory potential – makes oral diseases highly prevalent and therapeutically challenging. Metal-organic frameworks ...

Oral mucosal ageing represents a fundamental reprogramming of the tissue microenvironment, a dynamic process that underlies the functional decline and heightened disease susceptibility observed in the elderly. This revie...

ABSTRACT: Dental and maxillofacial injuries represent an important but underrecognised component of trauma during episodes of violent crowd control. Blunt and projectile forces directed toward the head frequently result ...

Introduction and aims: Additive manufacturing technology has the potential to produce accurate restorations in the field of prosthodontics. This in vitro study aimed to investigate the dimensional accuracy and marginal a...

Introduction and aims: Oral lichen planus (OLP), a chronic inflammatory oral mucosal disorder with malignant potential, has been associated with oral microbial dysbiosis. While bacterial community alterations in OLP are ...

ABSTRACT: Objective: To investigate the effects of commonly prescribed antibiotics and nonsteroidal anti-inflammatory drugs (NSAIDs) during early life on enamel development through a systematic review with quantitative ...

ABSTRACT: Objective: While diabetes is known to impair dentin regenerative capacity, the specific role of endothelial nitric oxide synthase (eNOS) is poorly defined. This study aimed to elucidate how eNOS regulates the ...

ABSTRACT: Background: Anoikis plays an important role in cancer metastasis. Nevertheless, research that focuses on the prognostic values of anoikis-related genes (ARGs) in oral squamous cell carcinoma (OSCC) is still sc...

Objective: Periodontally accelerated osteogenic orthodontics (PAOO) combines selective alveolar decortication with orthodontic force to accelerate tooth movement, but its influence on the gingival crevicular fluid (GCF) ...

Objective: Periodontitis is a chronic inflammatory disease that severely affects oral and general health. N7-methylguanosine (m7G) methylation plays critical roles in regulating gene expression and cellular functions. Me...

Background: The progression of pulpitis is strongly affected by the fate of dental pulp cells, with their modes of cell death determining whether inflammation resolves or leads to irreversible necrosis. Cuproptosis, a co...

Introduction and aims: Increasing evidence suggests that marginal zone B and B1 cell-specific protein (MZB1) plays crucial roles in inflammatory responses, endoplasmic reticulum (ER) stress, and cell survival, but its fu...

Background: Spinal cord injury (SCI) has emerged as a major challenge to global public health due to its low recovery rate and high disability rate, making the development of novel therapeutic approaches imperative. Mese...

Background: Accurate prediction of facial aesthetics after orthodontic treatment is crucial for clinical planning, yet traditional methodologies often lack the required accuracy and realism. We introduce a novel generati...

Introduction and aims: Human dental pulp stem cells (hDPSCs) play pivotal roles in the regeneration of pulp-dentin complex, yet their odontogenic differentiation is critically modulated by the inflammatory microenvironme...

Objective: Phosphatase and tensin homolog (PTEN) is a critical regulator of cell proliferation, differentiation, and inflammatory balance. However, its downstream proteomic effects in periodontal ligament stem cells (PDL...

Objective: This study aimed to evaluate and compare the dentinal tubule-occluding efficacy of various desensitising toothpastes and a sodium fluoride varnish using a subnanolitre scaled fluid flow measuring device (NFMD)...

Introduction and aims: Interleukin (IL)-38 has been identified as an anti-inflammatory cytokine; however, its specific role in temporomandibular joint (TMJ) synovial inflammation and the identity of its functional recept...