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Background: Adults aged 75 years and older carry the highest absolute risk of cardiovascular disease (CVD) yet remain substantially underrepresented in randomized trials evaluating statin therapy for primary prevention. ...

Objectives: To comprehensively analyse the burden of five oral diseases in China, including caries of deciduous teeth, caries of permanent teeth, periodontal diseases, edentulism, and other oral disorders; compare their ...

Background: As populations age and hypertension prevalence rises, the burden of hypertension-attributable chronic kidney disease (CKD) keeps aggregating and varies across regions. A systematic assessment of how disease b...

Introduction and Aims: Evidence suggests a relationship between oral microbiota and cardiovascular diseases (CVDs). However, the roles of specific microbiota in the pathogenesis of CVDs remain underexplored. Methods: Two...

Background: Metal-associated free fatty acids (FFAs) on cardiometabolic diseases have rarely been studied. Objective: To investigate metallomics-FFAs relationship, and identify FFAs as potential mediators linking metals ...

The characteristic oral environment – with its dynamic clearance, moisture, microbial load, and inflammatory potential – makes oral diseases highly prevalent and therapeutically challenging. Metal-organic frameworks ...