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Cyclodextrins (CDs)are a family of biodegradable cyclic hydrocarbons composed of α-(1,4)linked glucopyranose subunits, the more common containing 6, 7 or 8 glucose units are named α, β and γ-cyclodextrins respectivel...

The characteristic oral environment – with its dynamic clearance, moisture, microbial load, and inflammatory potential – makes oral diseases highly prevalent and therapeutically challenging. Metal-organic frameworks ...

In the search for new compounds for the treatment of Chagas disease, the cysteine protease cruzipain remains as one of the most attractive biomolecular targets for drug development. Thiosemicarbazones (TSCs) have been id...

Synthesis of new drugs, their rational design, or isolation from natural sources has decreased, and these facts lead to the use of currently marketed drugs. Some of them, extensively used, show unfavorable properties rel...