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Oral mucosal ageing represents a fundamental reprogramming of the tissue microenvironment, a dynamic process that underlies the functional decline and heightened disease susceptibility observed in the elderly. This revie...

Rheumatoid arthritis (RA) is an autoimmune disease that causes chronic synovial inflammation, progressive cartilage destruction, and bone erosion. Although there have been significant improvements in the use of conventio...

Benzo[a]pyrene (BaP), a widespread environmental pollutant, has been increasingly implicated in the pathogenesis of chronic degenerative diseases. Environmental pollutants have recently been recognized as emerging risk f...

Background: Barrett's esophagus (BE) represents a critical precancerous lesion arising from chronic gastroesophageal reflux disease (GERD), with significant risk of progression to esophageal adenocarcinoma. Despite advan...

Background: Periodontitis combined with orthodontic treatment creates a complex inflammatory and biomechanical microenvironment in gingival tissue, where macrophages play pivotal roles in tissue remodeling and immune reg...

Per- and polyfluoroalkyl substances (PFAS) are highly persistent environmental contaminants that pose potential ecological and health risks to humans and wildlife. This study investigated the comparative toxicity of four...