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Resveratrol, a natural polyphenol, may serve as a potential drug for pulmonary fibrosis (PF). This study uses meta-analysis and machine learning to assess resveratrol's efficacy and optimal treatment on PF animals. Four ...

Small sample sizes in preclinical research limit the extraction of reliable knowledge and hinder translational progress. We propose genESOM, a generative artificial intelligence method based on emergent self‑organizing...

Medicarpin (MED) is an isoflavonoid compound derived from traditional Chinese medicine (TCM). Numerous preliminary experimental studies have shown that MED has significant pharmacological effects in the treatment of canc...

Endothelial glycocalyx dysregulation remains the leading cause of the development and progression of cardiovascular diseases, which can increase the risk of organ failure and even cause death. However, the construction o...

Background: Osteoporosis has long been considered a disorder confined to bone tissue. Growing evidence now highlights its systemic origins, governed by intricate communication between multiple organs. The multi-organ-bon...

Rheumatoid arthritis (RA) is an autoimmune disease that causes chronic synovial inflammation, progressive cartilage destruction, and bone erosion. Although there have been significant improvements in the use of conventio...

Gene therapy holds a great potential for treating a variety of human disorders by introducing foreign therapeutic genetic material into target cells using gene carriers (vectors). Most particularly, viral vectors show a ...