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Objective: To generate synthetic Orthopantomograms (OPGs) using generative Artificial Intelligence (AI) models and to evaluate the realism of synthetic images through assessments by humans as well as AI models. Methodolo...

ABSTRACT: Introduction and aims: To provide the research progress on the cGAS-STING signalling pathway and its related roles in various oral diseases. Methods: We reviewed the recent research on cGAS-STING in PubMed. Th...

Introduction and Aims: Mandibular movement is a complex physiological process essential for orofacial function. Patients with disc displacement without reduction (DDWoR) exhibit significant kinematic impairments, which a...

Oral mucosal ageing represents a fundamental reprogramming of the tissue microenvironment, a dynamic process that underlies the functional decline and heightened disease susceptibility observed in the elderly. This revie...

Introduction: The advancement of AI-assisted oral disease diagnosis critically relies on the availability of annotated, high-quality datasets and resilient deep learning architectures. Nevertheless, progress in this doma...

This study aimed to evaluate the performance of deep learning models for segmenting the augmented bone following transalveolar sinus floor elevation (TSFE). Cone-beam computed tomography (CBCT) data from 103 patients und...

Introduction and aims: Conventional removable partial denture (RPD) clasp fabrication with wrought wire depends on operator skill, limiting efficiency and reproducibility. This study compared robotically and manually ben...

This work presents, for the frst time, the development of magnetic composites using activated biochar (BC-Act) derived from yerba mate waste. It includes an analysis of the effect of the activation process on the formati...

Introduction: This study aimed to identify dental pain using machine learning (ML) algorithms in Brazilian adolescents for public health screening purposes. Methods: Data from 2 cross-sectional waves of the Brazilian Nat...

Objectives: The minimum intervention oral health care (MIOC) delivery framework shifts restorative dentistry from a predominantly operative, procedure-centred model towards a person-focused, prevention-oriented and tooth...

Introduction and aims: While oral health status and psychosocial factors are associated with oral health-related quality of life (OHRQoL), the mechanisms remain unclear. This study aims to investigate their relationships...

Objective: Phosphatase and tensin homolog (PTEN) is a critical regulator of cell proliferation, differentiation, and inflammatory balance. However, its downstream proteomic effects in periodontal ligament stem cells (PDL...

Cerium-based materials were intensively studied in last years because of their high oxygen storage capacity (OSC) associated to the reversible Ce4+ Ce3+ process and their properties closely related to the defect chemistr...

Background: Outer membrane vesicles (OMVs) from Gram-negative bacteria are spherical lipid bilayer nanostructures with diameters of 20 to 250 nm. Porphyromonas gingivalis (P. gingivalis), a keystone periodontal pathogen,...

Objectives: By establishing a rat model of periapical infection, this study compared the anti‑inflammatory effects of caerin 1.1/1.9 hydrogel and calcium hydroxide paste, aiming to provide a novel therapeutic strategy ...

Objectives: This study aimed to develop an automated deep learning (DL) system to detect and classify second molar (M2) pathologies associated with impacted third molars (ITMs) on panoramic radiographs. We sought to enha...

Materias / palabras clave: Oral health; Global burden of disease; Health status indicators; Health care economics; Cost-effectiveness analysis; Quality-adjusted life years

Introduction and aims: Submucous cleft palate (SMCP) is a congenital craniofacial malformation. While TBX22 is a known pathogenic gene, the potential role of TBX15 in SMCP remains unclear. This study aimed to investigate...

ABSTRACT: Introduction: The links between oral health and female ageing are poorly understood, but many changes occur in the oral cavity of menopausal women that affect quality of life, and few current oral health inter...

Background and Objectives: Given the increasing use of artificial intelligence (AI) tools for dental health information, this study compared patients' perceived health information literacy for AI chatbots, measured using...

Introduction: Computer-aided design and computer-aided manufacturing (CAD/CAM) have transformed modern dentistry, yet evidence from the Caribbean remains limited. Objective: To assess CAD/CAM adoption among dentists in t...

The characteristic oral environment – with its dynamic clearance, moisture, microbial load, and inflammatory potential – makes oral diseases highly prevalent and therapeutically challenging. Metal-organic frameworks ...

Background: This study aims to evaluate the effectiveness and efficiency of combined multiple-case teaching (MCT) and narrative medicine teaching (NMT) method compared with lecture-based learning (LBL) in the clinical pr...