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Timely access to public healthcare is fundamental human rights and a key measure of social equity. In Thailand, transportation barriers especially in rural and underserved areas continue to restrict equitable access to m...

ObjectiveThis study aimed to identify core inflammatory biomarkers through machine learning approaches and develop an accessible online risk calculator to predict pulmonary consolidation in children with Chlamydia pneumo...

ObjectiveCongenital Hypogonadotropic Hypogonadism (CHH) is a rare disease with an extremely low incidence, and the outcomes of fertility induction therapy in CHH patients exhibit significant interindividual heterogeneity...

BackgroundGlobal population aging is accelerating, and China faces a significant challenge with “aging before affluent.” The disabled older adults population in China is projected to reach 58 million by 2050. Early i...

BackgroundTranscriptome−wide association study (TWAS) contributes to discovering novel susceptibility genes related to diseases. Single-cell RNA sequencing (scRNA-seq) has been extensively applied to characterize cellu...

BackgroundNon-suicidal self-injury (NSSI) is common among adolescents and young adults and remains difficult to detect early using conventional approaches. machine learning (ML) has increasingly been applied to develop p...

BackgroundOral submucosal fibrosis (OSF) is a chronic and progressive disorder, caused by chewing areca nuts, affecting the oral cavity and oropharynx. OSF is characterized by severe symptoms like severe burning sensatio...

BackgroundIntracranial infection (ICI) is a serious complication following spontaneous intracerebral hemorrhage (ICH) and is associated with prolonged intensive care, increased morbidity, and poor functional outcomes. Ea...

BackgroundChildhood obesity represents a significant global public health challenge. Accurate and rapid prediction models for identifying obesity risk in children and adolescents are essential for facilitating early prev...

ObjectiveDespite the widespread use of immune checkpoint inhibitors (ICIs) improving survival outcomes in non-small cell lung cancer (NSCLC) patients, immune-related adverse events (irAEs) triggered by ICIs have become a...

IntroductionThe COVID-19 pandemic has reduced system resilience, caused economic welfare loss, and widened disparities in healthcare access. This study aims to identify the macro-level factors contributing to COVID-19 va...

BackgroundYoung women with localized breast cancer represent a clinically distinct population with heterogeneous outcomes, yet age-specific prognostic models remain limited. Conventional risk stratification tools derived...

ObjectiveTo develop and internally validate an interpretable, non-invasive machine learning framework to predict detrusor underactivity (DU) in patients with benign prostatic hyperplasia (BPH).MethodsThis retrospective c...

BackgroundThere is limited understanding regarding the factors that predict recreational therapy engagement among veterans in long-term care facilities. We aimed to develop and validate machine learning models to predict...

BackgroundPersonal characteristics, income, social capital, and immigration policies influence immigrants’ social integration (SI) in European Union (EU) countries. However, few studies have used machine learning (ML) ...

Atherosclerosis, driven by elevated cholesterol levels, remains a major risk factor for cardiovascular disease. 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGR), the rate-limiting enzyme involved in cholesterol bio...

BackgroundSecondary hyperlipidemia is a common and serious complication in patients with clinically diagnosed depressive disorders, yet early screening tools are lacking. This study aims to develop and validate a machine...

Carbon allowances constitute a foundational component of national carbon emission control frameworks, as they govern the equitable distribution of subsequent allocations and directly shape the overall effectiveness of gr...

Cloud computing environments face persistent structural challenges in cost control, dynamic resource allocation, and security risk management, which traditional infrastructure approaches fail to address adequately. This ...

BackgroundChronic hepatitis B (CHB) caused by the hepatitis B virus (HBV) remains a major global health burden. The immune-active (IA) phase, characterized by positive Hepatitis B surface antigens (HBsAg), elevated alani...

IntroductionParkinson’s disease (PD) is the second most common neurodegenerative disorder. The risk of frailty is significantly higher in patients with PD than in age-matched individuals without PD. This study aimed to...

Background Lupus nephritis (LN) is a leading cause of mortality in patients with systemic lupus erythematosus (SLE), and the accurate classification of renal pathological subtypes is crucial for reducing mortality rates ...